Summary
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1.
Formulae are given for the probable errors of linkage and reduplication values calculated from the offspring of crosses of typesAB. ab ×abab, Ab.aB ×abab,AB.ab ×AB.ab, andAb.aB ×Ab. aB.
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2.
A method is given by which the best possible linkage values may be calculated from the offspring of the latter two crosses, i.e. fromF 2.
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3.
If this method is employed,F 2 is almost as accurate a means of measuring linkage as are the offspring fromF 1 × double recessive; it is also slightly more sensitive as a means for the detection of linkage.
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References
Todhunter.History of the Theory of Probability, p. 555.
Morgan andBridges. “ Sex-linked inheritance in Drosophila.”Carnegie Institution of Washington, 1916.
Altenburg.Genetics, Vol. I. p. 354, 1916.
Punnett.Journal of Genetics, Vol. VI. No. 3, 1917.
Bridges.American Naturalist, Vol. XLVIII. p. 524, 1914.
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Haldane, J.B.S. The probable errors of calculated linkage values, and the most accurate method of determining gametic from certain zygotic series. Journ. of Gen. 8, 291–297 (1919). https://doi.org/10.1007/BF02983270
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DOI: https://doi.org/10.1007/BF02983270