Abstract
Many newly synthesized proteins must be translocated across one or more membranes to reach their destination in the individual organelles or membrane systems. Translocation, mostly requiring an energy source, a signal on the protein itself, loose conformation of the protein and the presence of cytosolic and/or membrane receptor-like proteins, is often accompanied by covalent modifications of transported proteins. In this review I discuss these aspects of protein transportvia the classical secretory pathway and/or special translocation mechanisms in the unicellular eukaryotic organismSaccharomyces cerevisiae.
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Abbreviations
- Dol:
-
dolichyl (2,3-dihydropolyprenyl)
- ER:
-
endoplasmic reticulum
- NEM:
-
N-ethylmaleimide
- SDS:
-
sodium dodecyl sulfate
- ppαF:
-
pre-pro-α-factor
- ppKT:
-
pre-pro-killer toxin
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Horák, J. Protein transport and compartmentation in yeast. Folia Microbiol 36, 3–34 (1991). https://doi.org/10.1007/BF02935819
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DOI: https://doi.org/10.1007/BF02935819