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The biochemical control of the cell cycle by growth regulators in higher plants

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Abstract

The cell cycle is an important research field in cell biology and it is genetically and developmentally regulated in animals and plants. The aim of this study was to review knowledge about the biochemical regulation of the cell cycle by plant growth regulators through molecular checkpoints that regulate the transition from GO-G1-S-phase and G2-M in higher plants. Recent research has shown that zeatin treatment led to the up-regulation of CycD3 inArabidopsis. Benzyladenine treatment can also shorten the duration of S-phase through recruitment of latent origins of DNA replication. Kinetin is involved in the phosphoregulation of the G2-M checkpoint; the major cyclin-dependent kinase (Cdk) at this checkpoint has recently shown to be dephosphorylated as a result of cytokinin treatment, an effect that can also be mimicked by the fission yeast Cdc25 phosphatase. Gibberellic acid (GA) treatment induces internode elongation in deepwater rice, this response is mediated by a GA-induced up-regulation of a cyclin-Cdk at the G2-M checkpoint. Recent evidence has also linked abscisic acid to a cyclin-dependent kinase inhibitor. A new D-type cyclin, recently discovered inArabidopsis may have a key role in this process. A brief review on plant growth regulator-cell cycle interfacing during development and a cytokinin-induced continuum of cell cycle activation through the up-regulation of a plant D-type cyclin at the G1 checkpoint and the phosphoregulation of the Cdk at the G2/M checkpoint had been concluded. This review could be valuable to research on cell and developmental biology in plants.

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Authors and Affiliations

  1. Department of Biology, Howell Science Complex, East Carolina University, 27858-4353, Greenville, NC, USA

    Wei Tang, Latoya Harris & Ronald J. Newton

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  1. Wei Tang
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  2. Latoya Harris
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  3. Ronald J. Newton
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Biography: TANG Wei (1964-) male, Ph. Doctor, V. Assistant Professor, Department of Biology, Howell Science Complex. East Carolina University, Greenville, NC 27858-4353, USA.

Responsible editor: Chai Ruihai

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Tang, W., Harris, L. & Newton, R.J. The biochemical control of the cell cycle by growth regulators in higher plants. J. of For. Res. 15, 227–232 (2004). https://doi.org/10.1007/BF02911031

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