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Activity of fatty acyl CoA-lysophospholipid acyltransferases in liver microsomes of rats fed a choline-deficient diet

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Lipids

Abstract

Feeding a choline-deficient diet to rats has no effect on the activity of fatty acyl CoA-lysophospholipid acyltransferases, even though liver microsomes are severely depleted of lecithins. Thus lecithins appear to have no functional role in the activity of these transferases. It can be excluded that the latter enzymes are involved in the production of the changes in the fatty acid composition of liver phospholipids occurring in choline-deficient rats. These changes result most likely from alterations in the biosynthesis of liver lecithins and cephalins.

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Authors and Affiliations

  1. Department of Pathology, School of Medicine, University of Pittsburgh, 15213, Pittsburgh, Pennsylvania

    S. -H. Chen & B. Lombardi

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  1. S. -H. Chen
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  2. B. Lombardi
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Chen, S.H., Lombardi, B. Activity of fatty acyl CoA-lysophospholipid acyltransferases in liver microsomes of rats fed a choline-deficient diet. Lipids 8, 163–165 (1973). https://doi.org/10.1007/BF02544628

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  • DOI: https://doi.org/10.1007/BF02544628

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