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Temperature distribution under irradiation of pathologically changed tissue by an excimer laser

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Journal of Russian Laser Research Aims and scope

Abstract

A theoretical model of the temperature distribution of biological tissue under pulsed laser illumination is developed. With the help of the elaborated miniature thermometer based on a shieldless silicon transistor, the spatial-temporal distribution of temperatures of the artery inner wall with atherosclerotic inclusions (in vitro) under excimer-laser illumination as a function of laser power and the distance between the thermometer and laser spot on the tissue surface was experimentally measured. From a comparison of experimental data with the results of the model developed, the thermal diffusivity of tissue and the size of the “region of damage” (i.e., the region where the temperature exceeds 43–45°C) under laser removal (ablation) of the tissue was determined, as well as the threshold energy density of the ablation onset.

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References

  1. SPIEE'S International Symposium on Biomedical Optics “BIOS'98,” (Part of Photonics WEST) Technical Abstract Digest, San Jose Convention Center, San Jose, CA (1998).

  2. V. P. Zharov, B. V. Zubov, V. I. Loshchilov, et al., “Studies of optical and thermophysical properties of biological tissues by the pulsed photothermal radiometry method” [in Russian], Preprint of the Institute of General Physics, No. 146, Moscow (1987).

  3. S. Warren, K. Pope, Y. Yazdi, et al.,IEEE Trans. Biomed. Eng.,12, 121 (1995).

    Article  Google Scholar 

  4. F. H. Long and T. F. Deutsh,IEEE J Quant. Electron.,QE-23, 1821 (1987).

    Article  ADS  Google Scholar 

  5. V. Scharf, O. Eyal, and A. Katzir,Opt. Eng.,37, 2784 (1998).

    Article  ADS  Google Scholar 

  6. X. Barton, H.-J. Foth, M. Christ, et al.,App. Opt.,36, 32 (1997).

    ADS  Google Scholar 

  7. S. L. Jacques,Appl. Opt.,32, 247 (1993).

    Google Scholar 

  8. M. J. Morley,J. Food Technol.,1, 303 (1966).

    Article  Google Scholar 

  9. H. F. Bowman, E. G. Gravalho, and M. Woods,Annu. Rev. Biophys. Bioeng.,4, 43 (1975).

    Article  Google Scholar 

  10. D. O. Faminskii, S. A. Kolosov, T. I. Galkina, et al.,J. Russ., Laser Res.,18, 121 (1997).

    Google Scholar 

  11. Y. Loze and C. D. Wright,Appl. Opt.,37, 6822 (1998).

    Article  ADS  Google Scholar 

Download references

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Authors and Affiliations

  1. A. N. Bakulev Research Center of Cardiovascular Surgery, Russian Academy of Medical Sciences, Rublevskoe Sh. 135, 121552, Moscow, Russia

    D. O. Faminskii, I. M. Krestinich & S. Yu Kambarov

  2. P. N. Lebedev Physical Institute, Russian Academy of Sciences, Leninskii Pr. 53, 117924, Moscow, Russia

    A. Yu Klokov, A. I. Sharkov, S. A. Kolosov, T. I. Galkina, A. V. Tsikunov & A. F. Plotnikov

Authors
  1. D. O. Faminskii
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  2. A. Yu Klokov
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  3. A. I. Sharkov
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  4. S. A. Kolosov
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  5. T. I. Galkina
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  6. I. M. Krestinich
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  7. A. V. Tsikunov
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  8. S. Yu Kambarov
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  9. A. F. Plotnikov
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Additional information

Translated from a manuscript submitted November 27, 1998.

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Faminskii, D.O., Klokov, A.Y., Sharkov, A.I. et al. Temperature distribution under irradiation of pathologically changed tissue by an excimer laser. J Russ Laser Res 20, 202–210 (1999). https://doi.org/10.1007/BF02508539

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  • DOI: https://doi.org/10.1007/BF02508539

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