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HPTLC fluorescence enhancement of glutathione-SBD: Effect of cyclodextrins, triton and alkanes

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Summary

α-, β- and γ-cyclodextrins, Triton X-100 and n-alkanes (octadecane, paraffin, dodecane, and related compounds) used as dipping enhancers for the HPTLC densitometry of SBD-glutathione may lower the detection limits by a factor of about 2.

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Author notes

  1. B. Lin Ling

    Present address: Laboratory of Instrumental Techniques, Department of Bromatology and Pharmaceutical Analytical Techniques, Faculty of Pharmacy, Complutense University of Madrid, 28040, Madrid, Spain

Authors and Affiliations

  1. Laboratory of Pharmaceutical Chemistry and Drug Analysis, Faculty of Pharmaceutical Sciences, State University of Ghent, Harelbekestraat 72, B-9000, Ghent, Belgium

    W. R. G. Baeyens, B. Lin Ling & K. Stragier

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  1. W. R. G. Baeyens
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  2. B. Lin Ling
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  3. K. Stragier
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Baeyens, W.R.G., Ling, B.L. & Stragier, K. HPTLC fluorescence enhancement of glutathione-SBD: Effect of cyclodextrins, triton and alkanes. Chromatographia 29, 243–247 (1990). https://doi.org/10.1007/BF02317911

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  • DOI: https://doi.org/10.1007/BF02317911

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