Conclusions
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1.
The reaction of 2-methyl-3-indolethiol with acetylene gives the S-mono- and N,S-divinyl derivatives.
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2.
The reaction of 3-indolethiols with activated acetylenes occurs only on the sulfur atom. The reaction of 3-indolethiols with phenylacetylene takes place stereoselectively, giving the cis isomers, while the reaction with cyanoacetylenes mainly gives a mixture of Z- and E-isomers.
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G. G. Skvortsova, B. V. Trzhtsinskaya, L. F. Teterina, and V. S. Korytnyi, Khim.-Farm. Zh.,19, 976 (1985).
G. G. Skvortsova, B. V. Trzhtsinskaya, L. F. Teterina, et al., Khim.-Farm. Zh.,20, 51 (1986).
C. J. Krishna and C. Pooran, Pharmazie,37, 1 (1982).
G. G. Skvortsova, L. F. Teterina, B. V. Trzhtsinskaya, and V. K. Voronov, Khim. Geterotsikl. Soedin., 352 (1979).
B. V. Trzhtsinskaya, E. V. Rudakova, A. V. Afonin, et al., Izv. Akad. Nauk SSSR, Ser. Khim., 1674 (1986).
Yu. M. Skvortsov, A. G. Mal'kina, and B. A. Trofimov, Zh. Org. Khim.,19, 1351 (1987).
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 2, pp. 416–419, February, 1989.
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Trzhtsinskaya, B.V., Abramova, N.D., Teterina, L.F. et al. Reaction of 3-indolethiols with acetylenes. Russ Chem Bull 38, 363–366 (1989). https://doi.org/10.1007/BF00953630
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DOI: https://doi.org/10.1007/BF00953630