Abstract
Derivatives of 9,9-disubstituted 9,10-dihydro-9-sila-3-azaanthracene (compounds with possible biological activity) were synthesized by means of two methods. 10-β-Cyanoethyl derivatives were obtained by condensation of dihydrosilaazaanthracenes with acrylonitrole in the presence of Triton B. One of these products was reduced with lithium aluminum hydride to 9,9-dimethyl-10-(γ-aminopropyl)-9,10-dihydro-9-sila-3-azaanthracene. The second method involves conversion of dihydrosilaazaanthrones (obtained by oxidation of dihydrosilaazaanthracenes) to oximes followed by reduction of the latter with hydrazine hydrate in the presence of Raney nickel to give 10-amino derivatives. The latter were subjected to acylation.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1516–1520, November, 1982.
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Prostakov, N.S., Klochkov, A.M. & Varlamov, A.V. Amino derivatives of 9,9-diorgano-9,10-dihydro-9-sila-3-azaanthracene. Chem Heterocycl Compd 18, 1177–1181 (1982). https://doi.org/10.1007/BF00506368
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DOI: https://doi.org/10.1007/BF00506368