Journal of Materials Science

, Volume 48, Issue 1, pp 39–50 | Cite as

Biodegradable magnesium implants for orthopedic applications

  • Hazibullah Waizy
  • Jan-Marten Seitz
  • Janin Reifenrath
  • Andreas Weizbauer
  • Friedrich-Wilhelm Bach
  • Andrea Meyer-Lindenberg
  • Berend Denkena
  • Henning Windhagen


The clinical application of degradable orthopedic magnesium implants is a tangible vision in medical science. This interdisciplinary review discusses many different aspects of magnesium alloys comprising the manufacturing process and the latest research. We present the challenges of the manufacturing process of magnesium implants with the risk of contamination with impurities and its effect on corrosion. Furthermore, this paper provides a summary of the current examination methods used in in vitro and in vivo research of magnesium alloys. The influence of various parameters (most importantly the effect of the corrosive media) in in vitro studies and an overview about the current in vivo research is given.


Corrosion Rate Magnesium Alloy Corrosion Behavior Simulated Body Fluid Corrosive Medium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The authors gratefully acknowledge the financial support given by German research society (DFG) within the collaborative research project (SFB 599). We thank Christopher Müller for the design of Fig. 2.


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Hazibullah Waizy
    • 1
  • Jan-Marten Seitz
    • 2
  • Janin Reifenrath
    • 3
  • Andreas Weizbauer
    • 1
  • Friedrich-Wilhelm Bach
    • 2
  • Andrea Meyer-Lindenberg
    • 4
  • Berend Denkena
    • 5
  • Henning Windhagen
    • 1
  1. 1.Department of Orthopaedic SurgeryHannover Medical SchoolHannoverGermany
  2. 2.Institute of Materials ScienceLeibniz University of HannoverGarbsenGermany
  3. 3.Small Animal ClinicUniversity of Veterinary Medicine HannoverHannoverGermany
  4. 4.Clinic for Small Animal Surgery and Reproduction, Centre of Clinical Veterinary MedicineFaculty of Veterinary Medicine Ludwig-Maximilians-Universität MünchenMunichGermany
  5. 5.Institute of Production Engineering and Machine Tools (IFW)Leibnitz University of HannoverGarbsenGermany

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