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Biomechanical characterisation of a degradable magnesium-based (MgCa0.8) screw

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Abstract

Magnesium alloys have been in the focus of research in recent years as degradable biomaterial. The purpose of this study was the biomechanical characterisation of MgCa0.8-screws. The maximum pull out force of screws was determined in a synthetic bone without corrosion and after fixed intervals of corrosion: 24, 48, 72 and 96 h. This in vitro study has been carried out with Hank’s solution with a flow rate corresponding to the blood flow in natural bone. A maximum pull out force (Fmax) of 201.5 ± 9.3 N was measured without corrosion. The biomechanical parameter decreased by 30% after 96 h in corrosive medium compared to the non-corrosion group. A maximum load capacity of 28 ± 7.6 N/h was determined. Our biomechanical data suggests that this biodegradable screw provides a promising bone-screw-fixation and has great potential for medical application.

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Acknowledgements

The authors gratefully acknowledge the financial support given by German Research Society (DFG) within the collaborative research project (SFB 599).We thank Markus Badenhop for excellent technical support.

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, Hanover Medical School, Anna-von-Borries-Str.1-7, 30625, Hanover, Germany

    Hazibullah Waizy, Matthias Maibaum, Henning Windhagen & Fritz Thorey

  2. Laboratory for Biomechanics and Biomaterials, Hanover Medical School, Anna-von-Borries Str.1-7, 30625, Hanover, Germany

    Andreas Weizbauer & Frank Witte

  3. Institute of Production Engineering and Machine Tools (IFW), Leibnitz University of Hanover, An der Universität 2, 30823, Garbsen, Germany

    Arne Lucas & Berend Denkena

  4. Small Animal Clinic, School of Veterinary Medicine Hanover, Bischhofsholer Damm 15, 30173, Hanover, Germany

    Andrea Meyer-Lindenberg

Authors
  1. Hazibullah Waizy
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  2. Andreas Weizbauer
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  8. Andrea Meyer-Lindenberg
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Correspondence to Hazibullah Waizy.

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Waizy, H., Weizbauer, A., Maibaum, M. et al. Biomechanical characterisation of a degradable magnesium-based (MgCa0.8) screw. J Mater Sci: Mater Med 23, 649–655 (2012). https://doi.org/10.1007/s10856-011-4544-8

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  • DOI: https://doi.org/10.1007/s10856-011-4544-8

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