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Non-isothermal Kinetic Analysis of Synthesis of Medical Applicable Fluorapatite in Solid-state Reaction

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Abstract

This paper presents the synthesis of Fluorapatite particles (FA; Ca10 (PO4)6F2) as biomaterials for bone regeneration and dentistry. The particles were synthesized by mechanically activating CaHPO4, Ca(OH)2 and CaF2, which served as the precursor materials. Subsequently, the precursors were heated under a non-isothermal condition using simultaneous thermo-gravimetry (TG) and differential thermal analysis (DTA). The heating rates employed were 7, 10, and 15 °C min−1, and the process was conducted up to 1100 °C in an Ar atmosphere. The X-ray diffraction (XRD) was utilized to analyze the phase composition. To determine the activation energy variation with the degree of conversion (α), four isoconversional methods: starink, KAS, FWO, and Friedman were employed for the kinetic study of synthesizing Fluorapatite particles under non-isothermal conditions. The results indicate that the activation energy does not change with α. The empirical kinetic triplets (E, A, and g(a)) were calculated using a fitting model and the invariant kinetic parameters (IKP) method. By combining the isoconversional methods, IKP, and the fitting model, the obtained kinetic model was identified as Diffusion-controlled of third order (D3) with \(g\left(\alpha \right)={[1-{\left(1-a\right)}^\frac{1}{3}]}^{2}\).

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The raw/processed data required to reproduce these findings cannot be shared at this time due to legal or ethical reasons and technical or time limitations.

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Acknowledgements

The authors gratefully acknowledge Islamic Azad Najafabad university, Yazd universities for scholarship provided and partial support of this work.

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Authors and Affiliations

  1. Materials Engineering Department, Islamic Azad University, Najafabad Branch, Najafabad, Iran

    Seyed Yousef Mosavian & Reza Ebrahimi-Kahrizsangi

  2. Organic Group, Department of Chemistry, Yazd University, Yazd, Iran

    Zeinab Hamidi

  3. Nanotechnology Laboratory, Department of Chemistry, University of Isfahan, Isfahan, 81746-73441, Iran

    Janan Parhizkar

  4. Department of Chemistry, Faculty of Science, Arak University, Arak, Iran

    Farinaz Kamali

  5. Department of Basic Sciences, Payame Noor Mamasani University, Mamasani, Iran

    Seyed Davod Mosavian

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  1. Seyed Yousef Mosavian
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All authors have participated in (a) conception and design, or analysis and interpretation of the data; (b) drafting the article or revising it critically for important intellectual content; and (c) approval of the final version.

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Mosavian, S.Y., Ebrahimi-Kahrizsangi, R., Hamidi, Z. et al. Non-isothermal Kinetic Analysis of Synthesis of Medical Applicable Fluorapatite in Solid-state Reaction. Biomedical Materials & Devices (2024). https://doi.org/10.1007/s44174-024-00164-6

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