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Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension

  • Cardiac Magnetic Resonance (E Nagel and V Puntmann, Section Editors)
  • Published:
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Abstract

Quantitative magnetic resonance imaging provides a comprehensive and non-invasive assessment of the heart and lungs in patients with suspected pulmonary hypertension with the potential for accurate assessment of disease severity and response to treatment. Magnetic resonance imaging (MRI) can provide detailed reliable information of heart structure and function as the heart responds to elevated right ventricle afterload in patients with progressive pulmonary vascular disease; notably, progressive changes in right ventricle volume and function are of prognostic value independent of established biomarkers. This article reviews the current literature on MRI in pulmonary hypertension and also describes new and exciting developments in imaging of the heart, pulmonary vasculature and lungs, including assessment of myocardial changes with late gadolinium-enhanced imaging and T1 mapping, evaluating changes in the proximal pulmonary vasculature using image-based computational modelling and quantitative assessment of the capillary bed using MRI perfusion analysis.

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Authors and Affiliations

  1. Academic Unit of Radiology, University of Sheffield, Sheffield, UK

    Andrew J. Swift, Laura C. Saunders, Tom Sproson, Guilhem J. Collier, Helen Marshall & Jim M. Wild

  2. Sheffield Pulmonary Vascular Disease Unit, Sheffield, UK

    Nehal Hussain & David G. Kiely

  3. Institute for In Silico Medicine, University of Sheffield, Sheffield, UK

    Andrew J. Swift, David G. Kiely & Jim M. Wild

Authors
  1. Andrew J. Swift
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  2. Laura C. Saunders
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  3. Tom Sproson
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  4. Nehal Hussain
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  5. Guilhem J. Collier
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  6. Helen Marshall
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  7. David G. Kiely
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  8. Jim M. Wild
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Corresponding author

Correspondence to Andrew J. Swift.

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Conflict of Interest

Andrew J. Swift, Laura C. Saunders, Tom Sproson, Guilhem J. Collier, Helen Marshall and Jim M. Wild declare that they have no conflict of interest.

Nehal Hussain reports grants from Actelion.

David G. Kiely reports grants and personal fees from Actelion, grants and personal fees from Bayer, and personal fees from GSK.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Cardiac Magnetic Resonance

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Swift, A.J., Saunders, L.C., Sproson, T. et al. Multiparametric Magnetic Resonance Imaging in Pulmonary Hypertension. Curr Cardiovasc Imaging Rep 8, 45 (2015). https://doi.org/10.1007/s12410-015-9360-y

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  • DOI: https://doi.org/10.1007/s12410-015-9360-y

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