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C1 fractures: a review of diagnoses, management options, and outcomes

  • Cervical Injuries and Treatment (HJ Kim, Section Editor)
  • Published:
Current Reviews in Musculoskeletal Medicine Aims and scope Submit manuscript

Abstract

The atlas is subject to fracture under axial load, often due to traumatic injuries such as shallow dives and automobile accidents. These fractures account for 2–13 % of injuries to the cervical spine [Marcon RM et al. Clinics (Sao Paulo) 68(11):1455-61, 2013]. Fractures of the C1 vertebra are often difficult to diagnose, as there is often no neurological deficit or easily identifiable findings on radiographs. However, injuries to the atlas can be associated with vertebral artery injury and atlantoaxial or atlanto-occipital instability, making prompt and accurate diagnosis imperative. A detailed understanding of the anatomy, inherent stability, and common injury patterns is essential for any surgeon treating spinal trauma. This chapter explores the diagnosis and management of C1 fractures, as well as outcomes after treatment.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Marcon RM, Cristante AF, Teixeira WJ, Narasaki DK, Oliveira RP, De barros filho TE. Fractures of the cervical spine. Clinics (Sao Paulo). 2013;68(11):1455–61.

    Article  Google Scholar 

  2. Matthiessen C, Yohan R. Epidemiology of atlas fractures—a national registry-based cohort study of 1,537 cases. Spine J. 2015;15(11):2332–7. doi:10.1016/j.spinee.2015.06.052. Provides epidemiological data and related information for a large cohort of patients with C1 fractures.

    Article  PubMed  Google Scholar 

  3. Kakarla UK, Chang SW, Theodore N, Sonntag VK. Atlas fractures. Neurosurgery. 2010;66(3 Suppl):60–7.

    Article  PubMed  Google Scholar 

  4. Jefferson G. Fracture of the atlas vertebra: report of four cases, and a review of those previously recorded. Br J Surg. 1920;7(27):407–22. doi:10.1002/bjs.1800072713.

    Article  Google Scholar 

  5. Payabvash S, McKinney AM, McKinney ZJ, Palmer CS, Truwit CL. Screening and detection of blunt vertebral artery injury in patients with upper cervical fractures: the role of cervical CT and CT angiography. Eur J Radiol. 2014;83(3):571–7. doi:10.1016/j.ejrad.2013.11.020.

    Article  PubMed  Google Scholar 

  6. Hadley MN, Curtis DA, Browner CM, Sonntag VKH. Acute traumatic atlas fractures: management and long term outcome. Neurosurgery. 1988;23(1):31–5.

    Article  CAS  PubMed  Google Scholar 

  7. Garrett M, Consiglieri G, Kakarla UK, Chang SW, Dickman CA. Occipitoatlantal dislocation. Neurosurgery. 2010;66(3):A48–55. doi:10.1227/01.NEU.0000365802.02410.C5.

    Article  Google Scholar 

  8. Gray H, Warren HL, Inc Bartleby.com. Anatomy of the human body. New York: Bartleby.com; 2000. http://www.bartleby.com/107/.

    Google Scholar 

  9. Radcliff KE, Sonagli MA, Rodrigues LM, Sidhu GS, Albert TJ, Vaccaro AR. Does C1 fracture displacement correlate with transverse ligament integrity? Orthop Surg. 2013;5(2):94–9. doi:10.1111/os.12034.

    Article  PubMed  Google Scholar 

  10. Jackson RS, Banit DM, Rhyne AL, Darden BV. Upper cervical spine injuries. J Am Acad Orthop Surg. 2002;10(4):271–80.

    Article  PubMed  Google Scholar 

  11. Lee C, Woodring JH. Unstable Jefferson variant atlas fractures: an unrecognized cervical injury. AJNR Am J Neuroradiol. 1991;12(6):1105–10. PMID 1763734.

    CAS  PubMed  Google Scholar 

  12. Gehweiler J, Daffner RH, Roberts L. Malformations of the atlas vertebra simulating the Jefferson fracture. Am J Roentgenol. 1983;140(6):1083–6. doi:10.2214/ajr.140.6.1083.

    Article  Google Scholar 

  13. de Zoete A, Langeveld UA. A congenital anomaly of the atlas as a diagnostic dilemma: a case report. J Manipulative Physiol Ther. 2007;30(1):62–4.

    Article  PubMed  Google Scholar 

  14. Hadley MN. Isolated fractures of the atlas in adults. Neurosurg. 2002;50:S120–4.

    Article  Google Scholar 

  15. Chaput CD, Walgama J, Torres E, Dominguez D, Hanson J, Song J, et al. Defining and detecting missed ligamentous injuries of the occipitocervical complex. Spine. 2011;36(9):709–14. doi:10.1097/BRS.0b013e3181de4ec1.

    Article  PubMed  Google Scholar 

  16. Deliganis AV, Mann FA, Grady MS. Rapid diagnosis and treatment of a traumatic atlantooccipital dissociation. Am J Roentgenol. 1998;171(4):986.

    Article  CAS  Google Scholar 

  17. Pang D, Nemzek WR, Zovickian J. Atlanto-occipital dislocation–part 2: the clinical use of (occipital) condyle-c1 interval, comparison with other diagnostic methods, and the manifestation, management, and outcome of atlanto-occipital dislocation in children. Neurosurgery. 2007;61(5):995–1015. doi:10.1227/01.neu.0000303196.87672.78. discussion 1015.

    Article  PubMed  Google Scholar 

  18. Joaquim AF, Ghizoni E, Tedeschi H, Lawrence B, Brodke DS, Vaccaro AR, et al. Upper cervical injuries—a rational approach to guide surgical management. J Spinal Cord Med. 2014;37(2):139–51. doi:10.1179/2045772313Y.0000000158.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Joaquim AF, Ghizon E, Tedeschi H, Yacoub ARD, Brodke DS, Vaccaro AR, et al. Upper cervical injuries: clinical results using a new treatment algorithm. J Craniovertebral Junction & Spine. 2015;6(1):16–20. doi:10.4103/0974-8237.151585. Describes the indications for surgery versus conservative management.

    Article  Google Scholar 

  20. Lee TT, Green BA, Petrin DR. Treatment of stable burst fracture of the atlas (Jefferson fracture) with rigid cervical collar. Spine. 1998;23(18):1963–7.

    Article  CAS  PubMed  Google Scholar 

  21. Lauweryns P. Role of conservative treatment of cervical spine injuries. Eur Spine J. 2010;19 Suppl 1:23–6. doi:10.1007/s00586-009-1116-4.

    Article  Google Scholar 

  22. Benzel EC, Hadden TA, Saulsbery CM. A comparison of the Minerva and halo jackets for stabilization of the cervical spine. J Neurosurg. 1989;70(3):411–4. doi:10.3171/jns.1989.70.3.0411.

    Article  CAS  PubMed  Google Scholar 

  23. Shin JJ, Kim SJ, Kim TH, Shin HS, Hwang YS, Park SK. Optimal use of the halo-vest orthosis for upper cervical spine injuries. Yonsei Med J. 2010;51(5):648–52. doi:10.3349/ymj.2010.51.5.648.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Benzel EC, Larson SJ, Kerk JJ, Millington PJ, Novak SM, Falkner RH, et al. The thermoplastic Minerva body jacket: a clinical comparison with other cervical spine splinting techniques. J Spinal Disord. 1992;5(3):311–9.

    Article  CAS  PubMed  Google Scholar 

  25. Costa F, Ortolina A, Attuati L, Cardia A, Tomei M, Riva M, et al. Management of C1–2 traumatic fractures using an intraoperative 3D imaging-based navigation system. J Neurosurg Spine. 2014;22(2):128–33. doi:10.3171/2014.10.SPINE14122.

    Article  PubMed  Google Scholar 

  26. Andersson S, Rodrigues M, Olerud C. Odontoid fractures: high complication rate associated with anterior screw fixation in the elderly. Eur Spine J. 2000;9(1):56–9. doi:10.1007/s005860050009.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Guo Q, Deng Y, Wang J, Liang W, Lu X, Guo X, et al. Comparison of clinical outcomes of posterior C1-2 temporary fixation without fusion and C1-2 fusion for fresh odontoid fractures. Neurosurg. 2015;4:77–83. doi:10.1227/NEU.0000000000001006.

    Google Scholar 

  28. Sattarov K, Skoch J, Abbasifard S, Patel AS, Avila MJ, Walter CM, et al. Posterior atlantoaxial fixation: a cadaveric and fluoroscopic step-by-step technical guide. Surg Neurol Int. 2015;6(4):S244–7. doi:10.4103/2152-7806.156611. Details the procedure for the Goel-Harms technique of atlantoaxial fixation.

    PubMed  PubMed Central  Google Scholar 

  29. Goel A, Desai KI, Muzumdar DP. Atlantoaxial fixation using plate and screw method: a report of 160 treated patients. Neurosurg. 2002;51(6):1351–7. doi:10.1227/01.NEU.0000309110.78968.F5.

    Google Scholar 

  30. SV Patkar. “Sub-Facetal C2 body screw in posterior fixation (Goel-Harm’s technique) of the atlanto-axial joint avoiding the vertebral artery.” The Internet Journal of Neurosurgery 10, no. 1. Accessed September 20, 2015. http://print.ispub.com/api/0/ispub-article/14745.

  31. Mummaneni PV, Haid RW. Atlantoaxial fixation: overview of all techniques. Neurol India. 2005;53(4):408–15.

    Article  PubMed  Google Scholar 

  32. Floyd T, Grob D. Translaminar screws in the atlas. Spine. 2000;25(22):2913–5.

    Article  CAS  PubMed  Google Scholar 

  33. Koller H, Resch H, Tauber M, Zenner J, Augat P, Penzkofer R, et al. A biomechanical rationale for C1-ring osteosynthesis as treatment for displaced Jefferson burst fractures with incompetency of the transverse atlantal ligament. Eur Spine J. 2010;19(8):1288–98. doi:10.1007/s00586-010-1380-3.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Muratsu H, Doita M, Yanagi T, Sekiguchi K, Nishida K, Tomioka M, et al. Cerebellar infarction resulting from vertebral artery occlusion associated with a Jefferson fracture. J Spinal Disord Tech. 2005;18(3):293–6.

    PubMed  Google Scholar 

  35. Bransford R, Chapman JR, Bellabarba C. Primary internal fixation of unilateral C1 lateral mass sagittal split fractures: a series of 3 cases. J Spinal Disord Tech. 2011;24(3):157–63. doi:10.1097/BSD.0b013e3181e12419.

    Article  PubMed  Google Scholar 

  36. Shatsky J, Bellabarba C, Nguyen Q, Bransford RJ. A retrospective review of fixation of C1 ring fractures—does the transverse atlantal ligament (TAL) really matter? Spine J. 2015. doi:10.1016/j.spinee.2015.11.041.

    PubMed  Google Scholar 

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Correspondence to Loren B. Mead II.

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Loren B. Mead II and Jonathan Krystal declare that they have no conflict of interest. Paul W. Millhouse reports financial relations with Globus Medical, outside the submitted work. Alexander R. Vaccaro reports other from Replication Medica, personal fees from DePuy, personal fees from Medtronics, personal fees from Stryker Spine, personal fees and other from Globus, other from Paradigm Spine, personal fees and other from Stout Medical, other from Progressive Spinal Technologies, other from Advanced Spinal Intellectual Properties, personal fees from Aesculap, other from Spine Medica, other from Computational Biodynamics, other from Spinology, other from In Vivo, other from Flagship Surgical, other from Cytonics, other from Bonovo Orthopaedics, other from Electrocore, other from Gamma Spine, other from Location Based Intelligence, other from FlowPharma, personal fees from Gerson Lehrman Group, personal fees from Guidepoint Global, personal fees from Medacorp, other from Rothman Institute and Related Properties, other from AO Spine, personal fees and other from Innovative Surgical Design, other from Association of Collaborative Spine Research, personal fees from Orthobullets, personal fees from Thieme, personal fees from Jaypee, personal fees from Elsevier, personal fees from Taylor Francis/Hodder and Stoughton, personal fees from Expert Testimony, personal fees from Ellipse, other from Vertiflex, other from Avaz Surgical, other from Clinical Spine Surgery, other from Spine Journal, other from Prime Surgeons, outside the submitted work.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Cervical Injuries and Treatment

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Mead, L.B., Millhouse, P.W., Krystal, J. et al. C1 fractures: a review of diagnoses, management options, and outcomes. Curr Rev Musculoskelet Med 9, 255–262 (2016). https://doi.org/10.1007/s12178-016-9356-5

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