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The Arrangement of MicroRNAs in the Regulation of Drought Stress Response in Plants: A Systematic Review

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Abstract

MiRNAs have received much attention over the last 2 decades as one of the major regulators of drought response in the plant. However, there has been little systematic discussion of the identified drought-responsive miRNAs. This paper is an overview of conducted studies until March 1, 2020, to identify frequent drought-responsive miRNAs (DRMs), their expression patterns, and functional roles. The present study organized 5628 records of detected DRMs from 40 flowering plants. Based on the available data, 72% of these DRMs are detected by deep sequencing techniques. Oryza Sativa was uncovered as the most frequently studied species under drought stress. Likewise, leaf tissue was detected as the most examined tissue. The present study noticed dissimilar expression patterns of DRMs in the various plant species which could be exemplified in Oryza sativa and Triticum aestivum that their DRMs were more promoted and inhibited under drought stress, respectively. Results of this study proposed miR166, miR169, miR172, miR396, and miR399 as frequently down-regulated DRMs while miR160 was suggested as an up-regulated DRM in many instances. Based on the reported data, it would seem to suggest a reverses expression patterns for some DRMs between drought tolerant and sensitive varieties (like miR156, miR159, miR395, and miR393) or shoot and root tissues (like miR156, miR171, and miR812). According to the previous functional studies of miRNAs, miR156, miR529, miR1119, miR159, miR172, miR319, miR394, and miR396 were categorized as positive regulators while mir166, miR160, and miR1916 were classified as negative regulators of drought stress tolerance induction. The outcome of various experiments led to the conclusion that although miRNAs are numerous with dynamic activity, a systematical study could uncover their discipline in the regulation of environmental stresses.

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Data Availability

The datasets generated and analysed during the current study are available in the Supplementary file 1.

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  1. Horticulture Crops Research Department, Sistan Agricultural and Natural Resources Research and Education Center, AREEO, Zabol, Iran

    Behnam Bakhshi

  2. Department of Plant Production and Genetics, Faculty of Agriculture, University of Zanjan, Zanjan, Iran

    Ehsan Mohseni Fard

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  1. Behnam Bakhshi
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Bakhshi, B., Fard, E.M. The Arrangement of MicroRNAs in the Regulation of Drought Stress Response in Plants: A Systematic Review. Plant Mol Biol Rep 41, 369–387 (2023). https://doi.org/10.1007/s11105-023-01380-y

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