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Perovskite nanoparticles as a sensing platform for electrochemical glucose detection

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Abstract

Rare-earth PrFeO3 perovskite nanoparticles (NPs) were prepared by the ultrasonically assisted co-precipitation method. Highly crystalline structure, smooth surface, and irregular spherical shape with an average size of 30–35 nm were observed in TEM micrographs. The cyclic voltammetry (CV) technique was applied for the electrochemical detection of glucose concentrations in liquid samples, in which crystalline perovskite NPs utilized as a sensing platform. From electrochemistry, various electro-catalytic features of the as-designed electrode were investigated namely variable potential, scan speeds, the same potential for nine consecutive cycles, chronoameromatric (CA) analysis, interference sample analysis, and quantitative glucose detection in phosphate buffer solution (0.1 M PBS, pH 7.199). The fabricated electrode provided a wide glucose detection range (19.5–5000 µM), fast response, long linearity, and high sensitivity with a low detection limit (19.5 µM) because of efficient redox-coupled reaction. The sensitivity of the fabricated electrode was examined with time-dependent impact via chronoamperometry in the existence of glucose at four different voltages of + 0.05 to + 1.2 V from 0 to 1000s, showing outstanding results. Additionally, the sustainability of the fabricated electrode was examined by taking tap water samples from five distinct locations and underwent an actual sample analysis using perovskite/GCE. Monitoring the glucose level in the human body is an important task to control health-related complications like blood sugar, kidney disease, heart failure, etc. Therefore, glucose detection/sensing techniques are important to regulate the sugar levels in the human blood.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.

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Acknowledgements

The authors extend their appreciation to the Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia for funding this research work through project number IFKSURG-554.

Funding

This work is supported by Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia through the project number IFKSURG-554  

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Authors and Affiliations

  1. King Abdullah Institute for Nanotechnology, King Saud University, Riyadh, 11451, Saudi Arabia

    Anees A. Ansari & M. A. Majeed Khan

  2. Department of Chemistry, College of Sciences, King Saud University, Riyadh, 11451, Saudi Arabia

    M. Alam

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  1. Anees A. Ansari
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Contributions

AAA contributed to conceptualization, methodology, investigation, resources, writing—original draft, writing—review & editing, supervision, project administration, and funding acquisition. MAMK contributed to formal analysis and data curation. MA contributed to produce data, formal analysis, and data curation.

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Correspondence to Anees A. Ansari.

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Ansari, A.A., Khan, M.A.M. & Alam, M. Perovskite nanoparticles as a sensing platform for electrochemical glucose detection. J Mater Sci: Mater Electron 34, 991 (2023). https://doi.org/10.1007/s10854-023-10454-2

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