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Ultrasound Technologies for Biomaterials Fabrication and Imaging

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Abstract

Ultrasound is emerging as a powerful tool for developing biomaterials for regenerative medicine. Ultrasound technologies are finding wide-ranging, innovative applications for controlling the fabrication of bioengineered scaffolds, as well as for imaging and quantitatively monitoring the properties of engineered constructs both during fabrication processes and post-implantation. This review provides an overview of the biomedical applications of ultrasound for imaging and therapy, a tutorial of the physical mechanisms through which ultrasound can interact with biomaterials, and examples of how ultrasound technologies are being developed and applied for biomaterials fabrication processes, non-invasive imaging, and quantitative characterization of bioengineered scaffolds in vitro and in vivo.

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Acknowledgments

The authors thank Dr. Stephen McAleavey, Eric Comeau, and Karla Mercado (University of Rochester) for providing images.

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No conflicts of interest exist.

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Authors and Affiliations

  1. Department of Biomedical Engineering, University of Rochester, 310 Goergen Hall, P.O. Box 270168, Rochester, NY, 14627, USA

    Diane Dalecki & Denise C. Hocking

  2. Department of Pharmacology and Physiology, University of Rochester, 601 Elmwood Avenue, Box 711, Rochester, NY, 14642, USA

    Denise C. Hocking

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  1. Diane Dalecki
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Correspondence to Denise C. Hocking.

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Associate Editor Rosemarie Hunziker oversaw the review of this article.

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Dalecki, D., Hocking, D.C. Ultrasound Technologies for Biomaterials Fabrication and Imaging. Ann Biomed Eng 43, 747–761 (2015). https://doi.org/10.1007/s10439-014-1158-6

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