Skip to main content
SpringerLink
Log in

Titanium dioxide nanotube arrays modified with a nanocomposite of silver nanoparticles and reduced graphene oxide for electrochemical sensing

  • Original Paper
  • Published:
Microchimica Acta Aims and scope Submit manuscript

Abstract

We report on a new nanocomposite material for electrochemical sensing of hydrogen peroxide using a titanium dioxide nanotube arrays modified with reduced graphene oxide onto which silver nanoparticles (AgNPs) were chemically deposited. Transmission electron microscopy, scanning electron microscopy, X-ray diffraction, and energy-dispersive X-ray and Raman spectroscopy were used to characterize its microstructure and morphology. The results demonstrated that the AgNPs were uniformly dispersed on the surface of the modified electrode which was investigated with respect to capability for sensing hydrogen peroxide (H2O2). Under optimized experimental condition, the electrode responds to H2O2 with a sensitivity of 1152 μA mM−1 cm−2 at a working potential of −0.6 V. The current response is linearly related to the concentration of H2O2 in the range from 50 to 15.5 mM (with a correlation coefficient of 0.9997), and the detection limit is 2.2 μM. The sensor exhibits good stability and excellent selectivity for H2O2. By immobilizing glucose oxidase on the surface of this electrode, a glucose biosensor was obtained that responds to glucose in the 0.5 to 50 mM concentration range.

Schematic showing the preparation of TiO2NTs/r-GO/AgNPs nanocomposite

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Jang HD, Kim SK, Chang H, Roh K-M, Choi J-W, Huang J (2012) A glucose biosensor based on TiO2-graphene composite. Biosens Bioelectron 38(1):184–188

    Article  CAS  Google Scholar 

  2. Li J, Kuang D, Feng Y, Zhang F, Liu M (2012) Glucose biosensor based on glucose oxidase immobilized on a nanofilm composed of mesoporous hydroxyapatite, titanium dioxide, and modified with multi-walled carbon nanotubes. Microchim Acta 176(1–2):73–80

    Article  CAS  Google Scholar 

  3. Xie Y, Zhou L, Huang H (2007) Bioelectrocatalytic application of titania nanotube array for molecule detection. Biosens Bioelectron 22(12):2812–2818

    Article  CAS  Google Scholar 

  4. Lu X, Wang G, Zhai T, Yu M, Gan J, Tong Y, Li Y (2012) Hydrogenated TiO2 nanotube arrays for supercapacitors. Nano Lett 12(3):1690–1696

    Article  CAS  Google Scholar 

  5. Xie Y, Zhao Y (2013) Electrochemical biosensing based on polypyrrole/titania nanotube hybrid. Mater Sci Eng C 33(8):5028–5035

    Article  CAS  Google Scholar 

  6. Du H, Xie Y, Xia C, Wang W, Tian F (2014) Electrochemical capacitance of polypyrrole-titanium nitride and polypyrrole-titania nanotube hybrids. New J Chem 38(3):1284–1293

    Article  CAS  Google Scholar 

  7. Xie Y, Wang Y, Du H (2013) Electrochemical capacitance performance of titanium nitride nanoarray. Mater Sci Eng B 178(20):1443–1451

    Article  CAS  Google Scholar 

  8. Xia C, Xie Y, Wang Y, Wang W, Du H, Tian F (2013) Preparation and capacitance performance of polyaniline/titanium nitride nanotube hybrid. J Appl Electrochem 43(12):1225–1233

    Article  CAS  Google Scholar 

  9. Xie Y, Fang X (2014) Electrochemical flexible supercapacitor based on manganese dioxide-titanium nitride nanotube hybrid. Electrochim Acta 120:273–283

    Article  CAS  Google Scholar 

  10. Jiang Y, Zheng B, Du J, Liu G, Guo Y, Xiao D (2013) Electrophoresis deposition of Ag nanoparticles on TiO2 nanotube arrays electrode for hydrogen peroxide sensing. Talanta 112:129–135

    Article  CAS  Google Scholar 

  11. Kafi AKM, Wu G, Chen A (2008) A novel hydrogen peroxide biosensor based on the immobilization of horseradish peroxidase onto Au-modified titanium dioxide nanotube arrays. Biosens Bioelectron 24(4):566–571

    Article  CAS  Google Scholar 

  12. Kong L, Lu X, Bian X, Zhang W, Wang C (2010) A one-pot synthetic approach to prepare palladium nanoparticles embedded hierarchically porous TiO2 hollow spheres for hydrogen peroxide sensing. J Solid State Chem 183(10):2421–2425

    Article  CAS  Google Scholar 

  13. Arif Sher Shah MS, Zhang K, Park AR, Kim KS, Park N-G, Park JH, Yoo PJ (2013) Single-step solvothermal synthesis of mesoporous Ag-TiO2-reduced graphene oxide ternary composites with enhanced photocatalytic activity. Nanoscale 5(11):5093–5101

    Article  CAS  Google Scholar 

  14. German N, Ramanaviciene A, Voronovic J, Ramanavicius A (2010) Glucose biosensor based on graphite electrodes modified with glucose oxidase and colloidal gold nanoparticles. Microchim Acta 168(3–4):221–229

    Article  CAS  Google Scholar 

  15. Zhang Z, Xu F, Yang W, Guo M, Wang X, Zhang B, Tang J (2011) A facile one-pot method to high-quality Ag-graphene composite nanosheets for efficient surface-enhanced Raman scattering. Chem Commun 47(22):6440–6442

    Article  CAS  Google Scholar 

  16. Fan J, Shi Z, Ge Y, Wang J, Wang Y, Yin J (2012) Gum arabic assisted exfoliation and fabrication of Ag–graphene-based hybrids. J Mater Chem 22(27):13764–13772

    Article  CAS  Google Scholar 

  17. Badawy AME, Luxton TP, Silva RG, Scheckel KG, Suidan MT, Tolaymat TM (2010) Impact of environmental conditions (pH, ionic strength, and electrolyte type) on the surface charge and aggregation of silver nanoparticles suspensions. Environ Sci Technol 44(4):1260–1266

    Article  Google Scholar 

  18. Pérez-López B, Merkoçi A (2012) Carbon nanotubes and graphene in analytical sciences. Microchim Acta 179(1–2):1–16

    Article  Google Scholar 

  19. Wang Q, Yun Y (2013) Nonenzymatic sensor for hydrogen peroxide based on the electrodeposition of silver nanoparticles on poly(ionic liquid)-stabilized graphene sheets. Microchim Acta 180(3–4):261–268

    Article  CAS  Google Scholar 

  20. Moradi Golsheikh A, Huang NM, Lim HN, Zakaria R, Yin C-Y (2013) One-step electrodeposition synthesis of silver-nanoparticle-decorated graphene on indium-tin-oxide for enzymeless hydrogen peroxide detection. Carbon 62:405–412

    Article  CAS  Google Scholar 

  21. Gong H, Sun M, Fan R, Qian L (2013) One-step preparation of a composite consisting of graphene oxide, Prussian blue and chitosan for electrochemical sensing of hydrogen peroxide. Microchim Acta 180(3–4):295–301

    Article  CAS  Google Scholar 

  22. Chang Q, Tang H (2014) Optical determination of glucose and hydrogen peroxide using a nanocomposite prepared from glucose oxidase and magnetite nanoparticles immobilized on graphene oxide. Microchim Acta:1–8

  23. Liu C, Teng Y, Liu R, Luo S, Tang Y, Chen L, Cai Q (2011) Fabrication of graphene films on TiO2 nanotube arrays for photocatalytic application. Carbon 49(15):5312–5320

    Article  CAS  Google Scholar 

  24. Yun J-H, Wong RJ, Ng YH, Du A, Amal R (2012) Combined electrophoretic deposition–anodization method to fabricate reduced graphene oxide–TiO2 nanotube films. RSC Adv 2(21):8164–8171

    Article  CAS  Google Scholar 

  25. Song P, Zhang X, Sun M, Cui X, Lin Y (2012) Graphene oxide modified TiO2 nanotube arrays: enhanced visible light photoelectrochemical properties. Nanoscale 4(5):1800–1804

    Article  CAS  Google Scholar 

  26. Zhao H, Fu H, Zhao T, Wang L, Tan T (2012) Fabrication of small-sized silver NPs/graphene sheets for high-quality surface-enhanced raman scattering. J Colloid Interface Sci 375(1):30–34

    Article  CAS  Google Scholar 

  27. Ahmad M, Ahmed E, Hong ZL, Khalid NR, Ahmed W, Elhissi A (2013) Graphene-Ag/ZnO nanocomposites as high performance photocatalysts under visible light irradiation. J Alloys Compd 577:717–727

    Article  CAS  Google Scholar 

  28. Jin Z, Nackashi D, Lu W, Kittrell C, Tour JM (2010) Decoration, migration, and aggregation of palladium nanoparticles on graphene sheets. Chem Mater 22(20):5695–5699

    Article  CAS  Google Scholar 

  29. Cai W, Piner RD, Stadermann FJ, Park S, Shaibat MA, Ishii Y, Yang D, Velamakanni A, An SJ, Stoller M, An J, Chen D, Ruoff RS (2008) Synthesis and solid-state NMR structural characterization of 13C-labeled graphite oxide. Science 321(5897):1815–1817

    Article  CAS  Google Scholar 

  30. Tan E-Z, Yin P-G, T-t Y, Wang H, Guo L (2012) Three dimensional design of large-scale TiO2 nanorods scaffold decorated by silver nanoparticles as SERS sensor for ultrasensitive malachite green detection. ACS Appl Mater Interfaces 4(7):3432–3437

    Article  CAS  Google Scholar 

  31. Tung VC, Allen MJ, Yang Y, Kaner RB (2009) High-throughput solution processing of large-scale graphene. Nat Nanotechnol 4(1):25–29

    Article  CAS  Google Scholar 

  32. Alwarappan S, Liu C, Kumar A, Li C-Z (2010) Enzyme-doped graphene nanosheets for enhanced glucose biosensing. J Phys Chem C 114(30):12920–12924

    Article  CAS  Google Scholar 

  33. Gu Z, Yang S, Li Z, Sun X, Wang G, Fang Y, Liu J (2011) An ultrasensitive hydrogen peroxide biosensor based on electrocatalytic synergy of graphene-gold nanocomposite, CdTe-CdS core-shell quantum dots and gold nanoparticles. Anal Chim Acta 701(1):75–80

    Article  CAS  Google Scholar 

  34. Garjonyte R, Malinauskas A (2000) Amperometric glucose biosensors based on Prussian blue- and polyaniline-glucose oxidase modified electrodes. Biosens Bioelectron 15(9–10):445–451

    Article  CAS  Google Scholar 

  35. Wang W, Xie Y, Wang Y, Du H, Xia C, Tian F (2014) Glucose biosensor based on glucose oxidase immobilized on unhybridized titanium dioxide nanotube arrays. Microchim Acta 181(3–4):381–387

    Article  CAS  Google Scholar 

Download references

Acknowledgments

The work was supported by National Natural Science Foundation of China (No. 21373047 and 20871029), Research Fund for the Doctoral Program of Higher Education of China (No. 200802861071), Program for New Century Excellent Talents in University of the State Ministry of Education (No. NCET-08-0119), Science & Technology Program of Suzhou City (No. SYG201017, ZXG2012026, SYN201208) and the Open Research Fund of State Key Laboratory of Bioelectronics, Southeast University (No. 2011E17).

Author information

Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189, China

    Wei Wang, Yibing Xie, Chi Xia, Hongxiu Du & Fang Tian

  2. Suzhou Research Institute of Southeast University, Suzhou, 215123, China

    Wei Wang, Yibing Xie, Chi Xia & Hongxiu Du

Authors
  1. Wei Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Yibing Xie
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Chi Xia
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Hongxiu Du
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Fang Tian
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yibing Xie.

Electronic supplementary material

Below is the link to the electronic supplementary material.

ESM 1

(DOC 1.97 mb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Wang, W., Xie, Y., Xia, C. et al. Titanium dioxide nanotube arrays modified with a nanocomposite of silver nanoparticles and reduced graphene oxide for electrochemical sensing. Microchim Acta 181, 1325–1331 (2014). https://doi.org/10.1007/s00604-014-1258-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00604-014-1258-x

Keywords

Search

Navigation