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The Artemisia Genus: Panacea to Several Maladies

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Bioactive Natural products in Drug Discovery

Abstract

The genus Artemisia belongs to the family Asteraceae which has now become the subject of great attraction because of its rich species diversity and phytochemical composition. This genus has a very long history of use in the treatment of human diseases in different parts of the world. This medicinally important genus has promising therapeutic potential which includes antimalarial, anti-parasitic, hepato-protective, anti-nociceptive, anti-inflammatory, anti-ulcerogenic, antimicrobial, antitumour, antioxidant, anticancer, anticonvulsant, anti-leishmanial, anti-diabetic, anti-promastigote, antidepressant and anticonvulsant. A total of 839 chemical compounds (volatile and non-volatile) have been reported in different species of this genus. These chemical compounds can be categorised into major classes such as flavonoids, lignans, terpenes, fatty acids, phenylpropanoids, sterols, fatty esters, phenolics, hydrocarbons and miscellaneous compounds. Strategic conservation of Artemisia species shall continue to provide molecules of pharmaceutical importance in future.

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Abbreviations

2,4-D:

2,4-Dichlorophenoxyacetic acid

AA:

ascorbic acid

AIDS:

acquired immune deficiency syndrome

BAP:

6-benzylaminopurine

BC :

before the Christ’s birth

cm:

centimetre

DPPH:

1,1-diphenyl-2-picrylhydrazyl radical scavenging activity

FRAP:

ferric reducing antioxidant power

g:

gramme

HCl:

hydrochloric acid

HPLC:

high-performance liquid chromatography

HPTLC:

high-performance thin-layer chromatography

IAA:

indole 3-acetic acid

KN:

kinetin

mg:

milligrams

ml:

millilitre

MS:

Murashige and Skoog

MTCC:

Microbial Type Culture Collection and Gene Bank

NAA:

α-naphthalene acetic acid

TCM:

traditional Chinese medicine

μM:

micromolar

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  1. School of Bioengineering and Biosciences, Lovely Professional University, Phagwara, Punjab, India

    Bhupendra Koul

  2. Department of Chemistry, Government Science College, Chikhli, Gujarat, India

    Taslimahemad Khatri

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Correspondence to Bhupendra Koul .

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  1. Department of Microbiology, Lovely Professional University, Phagwara, Punjab, India

    Joginder Singh

  2. Department of Plant Pathology and Weed Research, Agricultural Research Organization, The Volcani Centre, Rishon Lezion, Israel

    Vineet Meshram

  3. Department of Biotechnology, Lovely Professional University, Phagwara, Punjab, India

    Mahiti Gupta

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Koul, B., Khatri, T. (2020). The Artemisia Genus: Panacea to Several Maladies. In: Singh, J., Meshram, V., Gupta, M. (eds) Bioactive Natural products in Drug Discovery. Springer, Singapore. https://doi.org/10.1007/978-981-15-1394-7_1

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