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Role of Functional MRI in the Management of Liver Metastases

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Functional Imaging in Oncology

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Abstract

Liver metastases are among the most common malignant liver lesions. Treatment options for liver metastases vary widely and depend mainly on imaging findings. Liver imaging in patients with liver metastases involves detection, characterization, staging, pretreatment evaluation, and assessment of response to treatment of metastases. In this chapter, we will discuss the role of MRI with special emphasis on functional techniques (diffusion-weighted imaging and dynamic contrast-enhanced imaging) for the diagnosis and management of liver metastases.

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Abbreviations

ADC:

Apparent diffusion coefficient

AUC:

Area under the curve

CRC:

Colorectal cancer

DCE:

Dynamic contrast enhancement

DWI:

Diffusion-weighted imaging

FSE:

Fast spin echo

GBCA:

Gadolinium-based contrast agent

HCC:

Hepatocellular carcinoma

HPI:

Hepatic perfusion index

IVIM:

Intravoxel incoherent motion

MRI:

Magnetic resonance imaging

RECIST:

Response Evaluation Criteria in Solid Tumors

RT-DWI:

Respiratory-triggered DWI

SI:

Signal intensity

SNR:

Signal-to-noise ratio

SPIO:

Superparamagnetic iron oxide

T1WI:

T1-weighted image

T2WI:

T2-weighted image

TTP:

Time to peak

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Author information

Authors and Affiliations

  1. CDPI Clinics, das Américas Avenue, 4666, Barra da Tijuca, Rio de Janeiro, Brazil

    Leonardo Kayat Bittencourt MD & Romulo Varella de Oliveira MD

  2. Rio de Janeiro Federal University, University City, Rio de Janeiro, Brazil

    Leonardo Kayat Bittencourt MD

  3. Rio de Janeiro State University, São Francisco Xavier Street, 524, Maracanã, Rio de Janeiro, Brazil

    Romulo Varella de Oliveira MD

  4. Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place, New York, NY, 10029, USA

    Bachir Taouli MD

Authors
  1. Leonardo Kayat Bittencourt MD
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  2. Romulo Varella de Oliveira MD
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  3. Bachir Taouli MD
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Corresponding author

Correspondence to Leonardo Kayat Bittencourt MD .

Editor information

Editors and Affiliations

  1. Health Time Group, Jaén, Spain

    Antonio Luna

  2. Clinica Girona Hospital Sta. Caterina, Gerona, Spain

    Joan C. Vilanova

  3. CDPI and IRM, Botafongo - Rio de Janeiro/RJ, Brazil

    L. Celso Hygino Da Cruz Jr.

  4. Centro de Diagnóstico Dr. Enrique Rossi, Buenos Aires, Argentina

    Santiago E. Rossi

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Bittencourt, L.K., de Oliveira, R.V., Taouli, B. (2014). Role of Functional MRI in the Management of Liver Metastases. In: Luna, A., Vilanova, J., Hygino Da Cruz Jr., L., Rossi, S. (eds) Functional Imaging in Oncology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40582-2_18

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  • DOI: https://doi.org/10.1007/978-3-642-40582-2_18

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