1. The dopaminergic nigrostriatal system

   • Klaus Unsicker

   From the Editor 01 September 2004 Pages: 1 - 1

2. The dopaminergic nigrostriatal system: development, physiology, disease

   • Oliver von Bohlen und Halbach
   • Kerstin Krieglstein
   • Jörg B. Schulz

   Editorial 01 September 2004 Pages: 3 - 3

3. Specification of midbrain territory

   • Nilima Prakash
   • Wolfgang Wurst

   Review 19 August 2004 Pages: 5 - 14

   

4. Midbrain-derived neural stem cells: from basic science to therapeutic approaches

   • Alexander Storch
   • Michael Sabolek
   • Johannes Schwarz

   Review 29 July 2004 Pages: 15 - 22

5. Induction and specification of midbrain dopaminergic cells: focus on SHH, FGF8, and TGF-β

   • Eleni Roussa
   • Kerstin Krieglstein

   Review 19 August 2004 Pages: 23 - 33

   

6. Homeobox gene Pitx3 and its role in the development of dopamine neurons of the substantia nigra

   • Marten P. Smidt
   • Simone M. Smits
   • J. Peter H. Burbach

   Review 06 August 2004 Pages: 35 - 43

   

7. Nurr1, an orphan nuclear receptor with essential functions in developing dopamine cells

   • Thomas Perlmann
   • Åsa Wallén-Mackenzie

   Review 01 September 2004 Pages: 45 - 52

   

8. Midbrain dopaminergic neurons: control of their cell fate by the engrailed transcription factors

   • Horst H. Simon
   • Sandrine Thuret
   • Lavinia Alberi

   Review 01 September 2004 Pages: 53 - 61

   

9. Ontogenic cell death in the nigrostriatal system

   • Robert E. Burke

   Review 03 September 2004 Pages: 63 - 72

   

10. Factors promoting survival of mesencephalic dopaminergic neurons

    • Kerstin Krieglstein

    Review 06 August 2004 Pages: 73 - 80

11. Histological changes of the dopaminergic nigrostriatal system in aging

    • A. K. Stark
    • B. Pakkenberg

    Review 08 September 2004 Pages: 81 - 92

12. Contrast enhancement: a physiological effect of striatal dopamine?

    • Saleem M. Nicola
    • F. Woodward Hopf
    • Gregory O. Hjelmstad

    Review 28 July 2004 Pages: 93 - 106

    

13. Innervation of the substantia nigra

    • Ulrich Misgeld

    Review 24 August 2004 Pages: 107 - 114

    

14. Parkinson’s disease: clinical aspects

    • Thomas Klockgether

    Review 08 September 2004 Pages: 115 - 120

15. Stages in the development of Parkinson’s disease-related pathology

    • Heiko Braak
    • Estifanos Ghebremedhin
    • Kelly Del Tredici

    Review 24 August 2004 Pages: 121 - 134

    

16. Neuronal pathology in Parkinson’s disease

    • Jörg B. Schulz
    • Björn H. Falkenburger

    Review 08 September 2004 Pages: 135 - 147

    

17. Cellular pathology of Parkinson’s disease: astrocytes, microglia and inflammation

    • Peter Teismann
    • Jörg B. Schulz

    Review 24 August 2004 Pages: 149 - 161

    

18. Synucleins and their relationship to Parkinson’s disease

    • Oliver von Bohlen und Halbach

    Review 24 July 2004 Pages: 163 - 174

    

19. Parkin-associated Parkinson’s disease

    • Rainer von Coelln
    • Valina L. Dawson
    • Ted M. Dawson

    Review 30 July 2004 Pages: 175 - 184

    

20. Causes of Parkinson’s disease: genetics of DJ-1

    • Patrick M. Abou-Sleiman
    • Daniel G. Healy
    • Nicholas W. Wood

    Review 26 June 2004 Pages: 185 - 188

21. Genetic causes of Parkinson’s disease: UCHL-1

    • Daniel G. Healy
    • Patrick M. Abou-Sleiman
    • Nicholas W. Wood

    Review 19 June 2004 Pages: 189 - 194

22. The role of synphilin-1 in synaptic function and protein degradation

    • Rejko Krüger

    Review 19 August 2004 Pages: 195 - 199

    

23. Redox imbalance

    • Daniela Berg
    • Moussa B. H. Youdim
    • Peter Riederer

    Review 10 September 2004 Pages: 201 - 213

    

24. Classic toxin-induced animal models of Parkinson’s disease: 6-OHDA and MPTP

    • Andreas Schober

    Review 28 July 2004 Pages: 215 - 224

    

25. Neurotoxicant-induced animal models of Parkinson’s disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration

    • Vladimir N. Uversky

    Review 16 July 2004 Pages: 225 - 241

    

26. Gene therapy in Parkinson’s disease

    • O. Eberhardt
    • J. B. Schulz

    Review 19 August 2004 Pages: 243 - 260

27. Stem cell therapy for Parkinson’s disease: where do we stand?

    • Laurent Roybon
    • Nicolaj S. Christophersen
    • Jia-Yi Li

    Review 11 August 2004 Pages: 261 - 273

    

28. Deep brain stimulation

    • Sorin Breit
    • Jörg B. Schulz
    • Alim-Louis Benabid

    Review 19 August 2004 Pages: 275 - 288