Articles

1. Immune-related transcriptomic and epigenetic reconfiguration in BV2 cells after lipopolysaccharide exposure: an in vitro omics integrative study

   • Arturo Marroquín-Rivera
   • Chenqi Zhao
   • Benoit Labonté

   Original Research Paper 12 January 2024 Pages: 211 - 225

   

2. Identification and validation of the association of Janus kinase 2 mutations with the response to immune checkpoint inhibitor therapy

   • Peipei Chen
   • Junyu Long
   • Kang Yu

   Original Research Paper Open access 10 January 2024 Pages: 263 - 276

   

3. CD8 + T cell-based molecular subtypes with heterogeneous immune landscapes and clinical significance in acute myeloid leukemia

   • Fangmin Zhong
   • Fangyi Yao
   • Xiaozhong Wang

   Original Research Paper 10 January 2024 Pages: 329 - 344

   

4. The NLRP3 inflammasome: a vital player in inflammation and mediating the anti-inflammatory effect of CBD

   • Feng-xin Chu
   • Xiao Wang
   • Bin Di

   Review 08 January 2024 Pages: 227 - 242

   

5. Alleviated NCOA4-mediated ferritinophagy protected RA FLSs from ferroptosis in lipopolysaccharide-induced inflammation under hypoxia

   • Yang Wang
   • Hongmei Ding
   • Fang Zheng

   Original Research Paper 08 January 2024 Pages: 363 - 379

   

6. Global evolving patterns and cross-country inequalities of inflammatory bowel disease burden from 1990 to 2019: a worldwide report

   • Lina Cao
   • Alimu Dayimu
   • Xiaoyun Yang

   Original Research Paper 07 January 2024 Pages: 277 - 287

   

7. 27-Hydroxycholesterol activates the GSK-3β/β-catenin signaling pathway resulting in intestinal fibrosis by inducing oxidative stress: effect of dietary interventions

   • Wei Xiao
   • Chunyan Hu
   • Zhong Li

   Original Research Paper 06 January 2024 Pages: 289 - 304

   

8. Activation of LXRs alleviates neuropathic pain-induced cognitive dysfunction by modulation of microglia polarization and synaptic plasticity via PI3K/AKT pathway

   • Siyi Han
   • Xiaoman Yuan
   • Xuebi Tian

   Original Research Paper 06 January 2024 Pages: 157 - 174

   

9. Prospective study of an adalimumab combined with partial enteral nutrition in the induction period of Crohn’s disease

   • Sisi Zhou
   • Zeyu Huang
   • Jing Yu

   Original Research Paper Open access 02 January 2024 Pages: 199 - 209

   

10. Granulocyte macrophage colony stimulating factor exerts dominant effects over macrophage colony stimulating factor during macrophage differentiation in vitro to induce an inflammatory phenotype

    • Maria Petrina
    • Torki Alothaimeen
    • Sameh Basta

    Original Research Paper 30 December 2023 Pages: 253 - 262

    

11. Axin2 depletion in macrophages alleviated senescence and increased immune response after myocardial infarction

    • Yue Zheng
    • Yuchao Wang
    • Tong Li

    Letter to the Editor 30 December 2023 Pages: 407 - 414

    

12. Anemoside B4, a new pyruvate carboxylase inhibitor, alleviates colitis by reprogramming macrophage function

    • Qing-hua Liang
    • Qiu-rong Li
    • Qiong-ming Xu

    Original Research Paper 29 December 2023 Pages: 345 - 362

    

13. Sphingosine 1-phosphate (S1P) receptor modulators as an induction and maintenance therapy for ulcerative colitis: a systematic review and meta-analysis of randomized controlled trials

    • Husam Abu Suilik
    • Fouad Jaber
    • Hassan Ghoz

    Original Research Paper 28 December 2023 Pages: 183 - 198

    

14. Porphyromonas gingivalis promotes the progression of oral squamous cell carcinoma by stimulating the release of neutrophil extracellular traps in the tumor immune microenvironment

    • Zhi-chen Guo
    • Si-li Jing
    • Si-jia Na

    Original Research Paper 27 December 2023 Pages: 693 - 705

    

15. Tangeretin attenuates acute lung injury in septic mice by inhibiting ROS-mediated NLRP3 inflammasome activation via regulating PLK1/AMPK/DRP1 signaling axis

    • Yuntao Liu
    • Yuting Zhang
    • Zhongde Zhang

    Original Research Paper 26 December 2023 Pages: 47 - 63

    

16. IL-4-secreting CD40L⁺ MAIT cells support antibody production in the peripheral blood of Heonch–Schönlein purpura patients

    • Muziying Liu
    • Ziqiang Yang
    • Tengchuan Jin

    Original Research Paper 26 December 2023 Pages: 35 - 46

    

17. Severity of critical illness correlates with CD3-low expression on iNKT-cells among septic surgical patients

    • Daithi S. Heffernan
    • Chun-Shiang Chung
    • Alfred Ayala

    Brief Report 26 December 2023 Pages: 1 - 4

    

18. Salmonella spvC gene suppresses macrophage/neutrophil antibacterial defense mediated by gasdermin D

    • Liting Zhou
    • Yuanyuan Li
    • Shuyan Wu

    Original Research Paper 23 December 2023 Pages: 19 - 33

    

19. Serum from COVID-19 patients promotes endothelial cell dysfunction through protease-activated receptor 2

    • Francesco Vieceli Dalla Sega
    • Francesca Fortini
    • Paola Rizzo

    Original Research Paper 20 December 2023 Pages: 117 - 130

    

20. Homer1 ameliorates ischemic stroke by inhibiting necroptosis-induced neuronal damage and neuroinflammation

    • Weihao Lv
    • Qianqian Zhang
    • Zhou Fei

    Original Research Paper Open access 13 December 2023 Pages: 131 - 144

    

21. The immunomodulatory effects of metformin in LPS-induced macrophages: an in vitro study

    • Zhiyong Wang
    • Min Wang
    • Pei Wei

    Brief Report 13 December 2023 Pages: 175 - 181

    

22. The clinical trajectory of peripheral blood immune cell subsets, T-cell activation, and cytokines in septic patients

    • Xuan Lu
    • Cong-Ying Song
    • Yuan-Qiang Lu

    Original Research Paper 12 December 2023 Pages: 145 - 155

    

23. Ecto-5ʹ-nucleotidase (CD73): an emerging role as prognostic factor in allergic sensitization

    • Silvana Morello
    • Carla Cicala

    Comment 12 December 2023 Pages: 111 - 115

    

24. Association of systemic inflammation with the obesity paradox in cancer: results from multi-cohort studies

    • Hailun Xie
    • Lishuang Wei
    • Hanping Shi

    Original Research Paper 12 December 2023 Pages: 243 - 252

    

25. Serine metabolism in macrophage polarization

    • Xinqiong Huang
    • Xue Yang
    • Yuping Chen

    Review 09 December 2023 Pages: 83 - 98

    

26. Insights into the complex interactions between Rab22a and extracellular vesicles in cancers

    • Shenghao Huang
    • Yuxuan Bao
    • Chunyan Hua

    Review 08 December 2023 Pages: 99 - 110

    

27. Unveiling the role of ABI3 and hub senescence-related genes in macrophage senescence for atherosclerotic plaque progression

    • Yajuan Fu
    • Juan Zhang
    • Yideng Jiang

    Original Research Paper Open access 07 December 2023 Pages: 65 - 82

    

28. O-GlcNAc modification of GSDMD attenuates LPS-induced endothelial cells pyroptosis

    • Fan Yu
    • Zhen Zhang
    • Alex F. Chen

    Original Research Paper Open access 14 November 2023 Pages: 5 - 17

    

29. Mutant p53^R211* ameliorates inflammatory arthritis in AIA rats via inhibition of TBK1-IRF3 innate immune response

    • Yaling Zeng
    • Jerome P. L. Ng
    • Vincent Kam Wai Wong

    Original Research Paper Open access 08 November 2023 Pages: 2199 - 2219

    

30. Targeting glycolytic pathway in fibroblast-like synoviocytes for rheumatoid arthritis therapy: challenges and opportunities

    • Qianwei Li
    • Yuehong Chen
    • Qibing Xie

    Review 08 November 2023 Pages: 2155 - 2167

    

31. Lidocaine pretreatment attenuates inflammatory response and protects against sepsis-induced acute lung injury via inhibiting potassium efflux-dependent NLRP3 activation

    • Kai Su
    • Xin-Tao Li
    • Fu-Shan Xue

    Original Research Paper 06 November 2023 Pages: 2221 - 2235

    

32. Mitochondrial dysfunction: a new molecular mechanism of intervertebral disc degeneration

    • Chao Song
    • Yulin Xu
    • Zongchao Liu

    Review 05 November 2023 Pages: 2249 - 2260

    

33. Effects of neutrophil fate on inflammation

    • Yuan Xiao
    • Yang Cheng
    • Yi Yang

    Review 05 November 2023 Pages: 2237 - 2248

    

34. STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation

    • Tianhui Yuan
    • Yuqi Xia
    • Fan Cheng

    Original Research Paper 04 November 2023 Pages: 2111 - 2126

    

35. Activation of the CD200/CD200R1 axis attenuates neuroinflammation and improves postoperative cognitive dysfunction via the PI3K/Akt/NF-κB signaling pathway in aged mice

    • Haitao Qian
    • Fei Gao
    • Xiaochun Zheng

    Original Research Paper 30 October 2023 Pages: 2127 - 2144

    

36. Identification of novel N7-methylguanine-related gene signatures associated with ulcerative colitis and the association with biological therapy

    • Lichao Yang
    • Lianwen Yuan

    Original Research Paper 27 October 2023 Pages: 2169 - 2180

    

37. Treg plasticity and human diseases

    • Zheng Zhang
    • Jihua Guo
    • Rong Jia

    Review 25 October 2023 Pages: 2181 - 2197

    

38. Application of omics in Sjögren’s syndrome

    • Wenqin He
    • Yangyang Lu
    • Dan Ma

    Review 25 October 2023 Pages: 2089 - 2109

    

39. Epigenetic regulation of 15-lipoxygenase-1 expression in human chondrocytes by promoter methylation

    • Sami G. Alsabri
    • Gadid G. Guedi
    • Hassan Fahmi

    Original Research Paper 24 October 2023 Pages: 2145 - 2153

    

40. A suitable model to investigate acute neurological consequences of coronavirus infection

    • Jordane Pimenta
    • Bruna Da Silva Oliveira
    • Vivian Vasconcelos Costa

    Original Research Paper 14 October 2023 Pages: 2073 - 2088

    

41. Ångstrom-scale silver particles ameliorate collagen-induced and K/BxN-transfer arthritis in mice via the suppression of inflammation and osteoclastogenesis

    • Ze-Hui He
    • Jing-Tao Zou
    • Hui Xie

    Original Research Paper 10 October 2023 Pages: 2053 - 2072

    

42. Role of histamine H₄ receptor in the anti-inflammatory pathway of glucocorticoid-induced leucin zipper (GILZ) in a model of lung fibrosis

    • Silvia Sgambellone
    • Marta Febo
    • Laura Lucarini

    Original Research Paper Open access 10 October 2023 Pages: 2037 - 2052

    

43. Targeting MyD88: Therapeutic mechanisms and potential applications of the specific inhibitor ST2825

    • Meiqi Liu
    • Wenyan Kang
    • Yang Zhang

    Review 09 October 2023 Pages: 2023 - 2036

    

44. Recombinant human diamine oxidase prevents hemodynamic effects of continuous histamine infusion in guinea pigs

    • Matthias Weiss-Tessbach
    • Birgit Reiter
    • Marlene Rager-Resch

    Original Research Paper Open access 09 October 2023 Pages: 2013 - 2022

    

45. Fraxetin alleviates BLM-induced idiopathic pulmonary fibrosis by inhibiting NCOA4-mediated epithelial cell ferroptosis

    • Xiaorun Zhai
    • Jingyu Zhu
    • Yunjuan Nie

    Original Research Paper 05 October 2023 Pages: 1999 - 2012

    

46. SGLT2 inhibitors prevent LPS-induced M1 macrophage polarization and alleviate inflammatory bowel disease by downregulating NHE1 expression

    • Ye Jin Kim
    • Jonghwa Jin
    • Keun-Gyu Park

    Original Research Paper 28 September 2023 Pages: 1981 - 1997

    

47. Advances of autoimmune rheumatic diseases related to malignant tumors

    • Miaomiao Zhao
    • Liangyu Mi
    • Ke Xu

    Review Open access 28 September 2023 Pages: 1965 - 1979

48. Kinins: Locally formed peptides during inflammation with potential use in tissue regeneration

    • Leonardo Martins
    • Michael Bader
    • João Bosco Pesquero

    Comment 26 September 2023 Pages: 1957 - 1963

    

49. GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis

    • Yuhong Xiao
    • Ye Yuan
    • Lingling Yu

    Original Research Paper 21 September 2023 Pages: 1941 - 1955

    

50. Nafamostat mesilate prevented caerulein-induced pancreatic injury by targeting HDAC6-mediated NLRP3 inflammasome activation

    • Peng Chen
    • Li-Jun Zhao
    • Jian-Dong Ren

    Original Research Paper 19 September 2023 Pages: 1919 - 1932