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Current Controversies in Metabolic Surgery for Nonalcoholic Fatty Liver Disease

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Abstract

Nonalcoholic fatty liver disease (NAFLD) represents the most common liver disease, and it is expected to become the leading cause of end-stage liver disease in the near future. Bariatric operations have beneficial effects on NAFLD, inducing histological resolution of liver damage through weight loss-dependent and weight loss-independent mechanisms. Due to lack of randomized controlled trials, no specific guidelines have been established so far. Yet there is growing evidence that NAFLD will eventually become a formal indication for metabolic surgery. Data regarding the choice of procedure are conflicting, although gastric bypass seems to be slightly superior to sleeve gastrectomy. The purpose of this review is to provide an update on the ongoing research regarding the role of metabolic surgery in NAFLD management.

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Authors and Affiliations

  1. Department of Bariatric and Metabolic Surgery, “HYGEIA” Hospital, 4 Erythrou Stavrou St., Marousi, PC 15126, Athens, Greece

    Iraklis Perysinakis & Harilaos C. Pappis

  2. Third Surgical Department, “George Gennimatas” General Hospital, 154 Mesogeion Av, PC 11527, Athens, Greece

    Elias Margaris

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  1. Iraklis Perysinakis
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Correspondence to Iraklis Perysinakis.

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Perysinakis, I., Pappis, H.C. & Margaris, E. Current Controversies in Metabolic Surgery for Nonalcoholic Fatty Liver Disease. OBES SURG 29, 1058–1067 (2019). https://doi.org/10.1007/s11695-019-03705-x

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