Abstract
Nonalcoholic steatohepatitis is becoming a common cause of liver cirrhosis and a significant number of patients undergoing bariatric surgery suffer with it. There is currently lack of consensus among surgeons regarding safety of bariatric surgery in patients with liver cirrhosis and the best bariatric procedure in these patients. This review investigates published English language scientific literature systematically in an attempt to answer these questions. Eleven studies that reported experience of bariatric surgery in cirrhotic obese patients were included in this review. This review shows an acceptably higher overall risk of complications and perioperative mortality with bariatric surgery in cirrhotic patients. Surgeons must discuss the possibility of an unexpected intraoperative diagnosis of cirrhosis preoperatively with all bariatric surgery patients and agree on a course of action.
Similar content being viewed by others
Abbreviations
- NAFLD:
-
Non-alcoholic fatty liver disease
- NASH:
-
Non-alcoholic steatohepatitis
- PRISMA:
-
Preferred reporting items for systematic reviews and meta-analyses
- RYGB:
-
Roux-en-Y gastric bypass
- SG:
-
Sleeve gastrectomy
- BPD:
-
Biliopancreatic diversion
- AGB:
-
Adjustable gastric banding
- DS:
-
Duodenal switch
- TIPS:
-
Transjugular intrahepatic portosystemic shunt
References
Angulo P. NAFLD, obesity and bariatric surgery. Gastroenterology. 2006;130(6):1848–52.
Weingarten TN, Swain JM, Kendrick ML, et al. Nonalcoholic steatohepatitis (NASH) does not increase complications after laparoscopic bariatric surgery. Obes Surg. 2011;21(11):1714–20.
Silverman JF, O’Brien KF, Long S, et al. Liver pathology in morbidly obese patients with and without diabetes. Am J Gastroenterol. 1990;85(10):1349–55.
Berzigotti A, Garcia-Tsao G, Bosch J, et al. Portal hypertension collaborative group. Obesity is an independent risk factor for clinical decompensation in patients with cirrhosis. Hepatology. 2011;54(2):555–61.
Kral JG, Thung SN, Biron S, et al. Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis. Surgery. 2004;135(1):48–58.
Takata MC, Campos GM, Ciovica R, et al. Laparoscopic bariatric surgery improves candidacy in morbidly obese patients awaiting transplantation. Surg Obes Relat Dis. 2008;4(2):159–64. discussion 164–5.
Millwala F, Nguyen GC, Thuluvath PJ. Outcomes of patients with cirrhosis undergoing non-hepatic surgery: Risk assessment and management. World J Gastroenterol. 2007;13(30):4056–63.
Csikesz NG, Nguyen LN, Tseng JF, et al. Nationwide volume and mortality after elective surgery in cirrhotic patients. J Am Coll Surg. 2009;208(1):96–103.
Mosko JD, Nguyen GC. Increased perioperative mortality following bariatric surgery among patients with cirrhosis. Clin Gastroenterol Hepatol. 2011;9(10):897–901.
Bromberger B, Porrett P, Choudhury R, et al. Weight loss interventions for morbidly obese patients with compensated cirrhosis: a Markov decision analysis model. J Gastrointest Surg. 2014;18(2):321–7.
Brolin RE, Bradley LJ, Taliwal RV. Unsuspected cirrhosis discovered during elective obesity operations. Arch Surg. 1998;133(1):84–8.
Shimizu H, Phuong V, Maia M, et al. Bariatric surgery in patients with liver cirrhosis. Surg Obes Relat Dis. 2013;9(1):1–6.
Rebibo L, Gerin O, Verhaeghe P, et al. Laparoscopic sleeve gastrectomy in patients with NASH-related cirrhosis: a case-matched study. Surg Obes Relat Dis. 2014;10(3):405–10.
Dallal RM, Mattar SG, Lord JL, et al. Results of laparoscopic gastric bypass in patients with cirrhosis. Obes Surg. 2004;14(1):47–53.
Sarr MG. Is a bariatric procedure appropriate in patients with portal hypertension secondary to cirrhosis? Surg Obes Relat Dis. 2006;2(3):405–6. discussion 406–7.
Woodford RM, Burton PR, O’Brien PE, et al. Laparoscopic adjustable gastric banding in patients with unexpected cirrhosis: Safety and outcomes. Obes Surg 2015. Feb 25 [Epub ahead of print].
Pestana L, Swain J, Dierkhising R, et al. Bariatric surgery in patients with cirrhosis with and without portal hypertension: a single-center experience. Mayo Clin Proc. 2015;90(2):209–15.
Diniz Mde F, Moura LD, Kelles SM, et al. Long-term mortality of patients submitted to Roux-en-Y gastric bypass in Public Health System: high prevalence of alcoholic cirrhosis and suicides. Arq Bras Cir Dig. 2013;26 Suppl 1:53–6.
Baltasar A. Liver cirrhosis and bariatric operations. Surg Obes Relat Dis. 2006;2(5):580.
Conflict of Interest
The authors declare that they have no competing interests.
Author Contribution
KM conceived the idea for the topic and wrote the manuscript. KM and AG independently collected information and analysed it. All authors participated in discussions on the topic. All authors have seen the final version and approve of it.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Jan, A., Narwaria, M. & Mahawar, K.K. A Systematic Review of Bariatric Surgery in Patients with Liver Cirrhosis. OBES SURG 25, 1518–1526 (2015). https://doi.org/10.1007/s11695-015-1727-2
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11695-015-1727-2