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Kinetic evaluation of the ethanolysis of phosphatidylcholine catalyzed by choline hydroxide

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Abstract

Anhydrous ethanol and choline hydroxide, which are friendlier to human beings, were applied in the process for preparing l-α-glycerophosphocholine. The mechanism of the ethanolysis of phosphatidylcholine catalyzed by choline hydroxide was proposed, the kinetics of the transesterification was evaluated under the catalyst concentration range of 0.006–0.018 mol/L and the temperature range of 293.15–323.15 K. The experimental data were well described by the pseudo-first order equation. The effects of nucleophilic reagent, concentration of catalyst, ethanol-to-oil molar ratios and the temperature were investigated, and the calculated activation energy was 24.28 kJ/mol.

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Acknowledgments

Authors are grateful for the supports from the Science and Technique Foundation of Shannxi (No. 2004K08 -C24) and the Industrialization foundation of Shaanxi Province Education Department (No. 04JC05).

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Authors and Affiliations

  1. School of Chemical Engineering, Northwest University, Xi’an, 710069, China

    Tiantian Zhang, Xiaoli Zhang, Hongya Li & Binxia Zhao

  2. College of Chemistry and Chemical Engineering, Longdong University, Gansu, 745000, China

    Tiantian Zhang

  3. Shaanxi Applied Physics and Chemistry Research Institute, Xi’an, 710061, China

    Weili Bai

Authors
  1. Tiantian Zhang
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  2. Xiaoli Zhang
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  3. Hongya Li
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  4. Weili Bai
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  5. Binxia Zhao
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Correspondence to Xiaoli Zhang.

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Zhang, T., Zhang, X., Li, H. et al. Kinetic evaluation of the ethanolysis of phosphatidylcholine catalyzed by choline hydroxide. Reac Kinet Mech Cat 110, 31–39 (2013). https://doi.org/10.1007/s11144-013-0579-9

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  • DOI: https://doi.org/10.1007/s11144-013-0579-9

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