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HIV-Related Research in Correctional Populations: Now is the Time

  • Behavioral Aspects of HIV Management (Ralph J. DiClemente and Jennifer Brown, Section Editors)
  • Published:
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Abstract

The incarcerated population has increased to unprecedented levels following the 1970 US declaration of war on illicit drug use. A substantial proportion of people with or at risk for HIV infection, including those with substance use and mental health disorders, have become incarcerated. The overlapping epidemics of incarceration and HIV present a need for academic medical centers to collaborate with the criminal justice system to improve the health of incarcerated populations. With coordinated collaboration and new programmatic initiatives it is possible to reduce HIV-associated risk behaviors and the likelihood of acquisition and transmission of HIV. Centers for AIDS Research (CFAR), funded by the National Institutes of Health, have proactively responded to this need through Collaboration on HIV in Corrections (CHIC) to improve the diagnosis, treatment, linkage to care, and prevention of HIV. This collaboration serves as a model for aligning academic expertise with criminal justice to confront this challenge to individual and public health. This is especially relevant given recent evidence of the effectiveness of antiretroviral therapy in reducing HIV transmission (Cohen et al. N Engl J Med 365(6):493–505, 2011).

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References

Papers of particular interest, published recently, have been highlighted as: •• Of major importance

  1. Cohen MS, Chen YQ, McCauley M et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365(6):493–505.

    Google Scholar 

  2. Pew Center on the States, One in 31: The Long Reach of American Corrections 2009: Washington, DC.

  3. Maruschak LM et al. Pandemic influenza and jail facilities and populations. Am J Public Health. 2009;99 Suppl 2:S339–44.

    Article  PubMed  Google Scholar 

  4. Spaulding AC et al. HIV/AIDS among inmates of and releasees from US correctional facilities, 2006: declining share of epidemic but persistent public health opportunity. PLoS One. 2009;4(11):e7558.

    Article  PubMed  Google Scholar 

  5. El-Sadr WM, Mayer KH, Hodder SL. AIDS in America–forgotten but not gone. N Engl J Med. 2010;362(11):967–70.

    Article  PubMed  CAS  Google Scholar 

  6. Springer SA, Azar MM, Altice FL. HIV, alcohol dependence, and the criminal justice system: a review and callfor evidence-based treatment for released prisoners. Am J Drug Alcohol Abuse. 2011;37(1):12–21.

    Google Scholar 

  7. Springer SA et al. Effectiveness of antiretroviral therapy among HIV-infected prisoners: reincarceration and the lack of sustained benefit after release to the community. Clin Infect Dis. 2004;38(12):1754–60.

    Article  PubMed  CAS  Google Scholar 

  8. Stephenson BL et al. Effect of release from prison and re-incarceration on the viral loads of HIV-infected individuals. Public Health Rep. 2005;120(1):84–8.

    PubMed  Google Scholar 

  9. Stephenson BL et al. Sexual behaviours of HIV-seropositive men and women following release from prison. Int J STD AIDS. 2006;17(2):103–8.

    Article  PubMed  Google Scholar 

  10. •• Rich JD, Wakeman SE, Dickman SL. Medicine and the epidemic of incarceration in the United States. N Engl J Med. 2011;364(22):2081-3. A disproportionate amount of incarceration in the US has been caused by the failed war on drugs and a failure to provide treatment to those with mental illnesses and addictions. While the medical and public health communities should capitalize on the opportunity to provide treatment to the largely uninsured, low-income, and minority population cycling through the criminal justice system, they also have the responsibility of advocating for alternatives to incarceration that address the health needs of underserved communities.

    Article  PubMed  CAS  Google Scholar 

  11. Raimer BG, Stobo JD. Health care delivery in the Texas prison system: the role of academic medicine. JAMA. 2004;292(4):485–9.

    Article  PubMed  CAS  Google Scholar 

  12. Beckwith CG et al. Feasibility and acceptability of rapid HIV testing in jail. AIDS Patient Care STDS. 2007;21(1):41–7.

    Article  PubMed  Google Scholar 

  13. Kavasery R et al. A prospective controlled trial of routine opt-out HIV testing in a men's jail. PLoS One. 2009;4(11):e8056.

    Article  PubMed  Google Scholar 

  14. Springer SA et al. Antiretroviral treatment regimen outcomes among HIV-infected prisoners. HIV Clin Trials. 2007;8(4):205–12.

    Article  PubMed  Google Scholar 

  15. Springer SA, Chen S, Altice FL. Improved HIV and substance abuse treatment outcomes for released HIV-infected prisoners: the impact of buprenorphine treatment. J Urban Health. 2010;87(4):592–602.

    Article  PubMed  Google Scholar 

  16. Lazzarini Z, Altice FL. A review of the legal and ethical issues for the conduct of HIV-related research in prisons. AIDS Public Policy J. 2000;15(3–4):105–35.

    PubMed  CAS  Google Scholar 

  17. Sabol WJ, Minton TD, Harrison PM. Prison and jail inmates at midyear, 2006. U.S. Department of Justice, 2007. Document NCJ 217675.

  18. ••Altice FL, et al. Treatment of medical, psychiatric, and substance-use comorbidities in people infected with HIV who use drugs. Lancet 2010;376(9738):367-87. This study provides an overview of comorbidities among HIV-positive people who use drugs and reviews treatment complications for those multiple conditions, particularly pharmacokinetic drug interactions and adherence problems.

    Article  PubMed  Google Scholar 

  19. Lobato MN, Leary LS, Simone PM. Treatment for latent TB in correctional facilities: a challenge for TB elimination. Am J Prev Med. 2003;24(3):249–53.

    Article  PubMed  Google Scholar 

  20. Mumola CJ, Karberg JC. Drug use and dependence, state and federal prisons, 2004. U.S. Department of Justice, 2006. Document NCJ 213530.

  21. Mattick RP, et al. Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence. Cochrane Database Syst Rev. 2008(2):CD002207.

  22. Binswanger IA et al. Release from prison–a high risk of death for former inmates. N Engl J Med. 2007;356(2):157–65.

    Article  PubMed  CAS  Google Scholar 

  23. Palepu A et al. Uptake and adherence to highly active antiretroviral therapy among HIV-infected people with alcohol and other substance use problems: the impact of substance abuse treatment. Addiction. 2004;99(3):361–8.

    Article  PubMed  Google Scholar 

  24. Kinlock TW et al. A randomized clinical trial of methadone maintenance for prisoners: results at 12 months postrelease. J Subst Abuse Treat. 2009;37(3):277–85.

    Article  PubMed  Google Scholar 

  25. Karberg J, James D. Substance dependence, abuse, and treatment of jail inmates, 2002. 2005: Washington, D.C.

  26. Mumola C. Substance abuse and treatment, state and federal prisoners, 1997. Justice UDo, 1999:1-16.

  27. Hendershot CS et al. Alcohol use and antiretroviral adherence: review and meta-analysis. J Acquir Immune Defic Syndr. 2009;52(2):180–202.

    Article  PubMed  Google Scholar 

  28. Palepu A et al. Alcohol use and incarceration adversely affect HIV-1 RNA suppression among injection drug users starting antiretroviral therapy. J Urban Health. 2003;80(4):667–75.

    Article  PubMed  Google Scholar 

  29. James DJ, Glaze LE. Mental health problems of prison and jail inmates. 2006. Bureau of Justice Statistics.

  30. Cook JA et al. Depressive symptoms and AIDS-related mortality among a multisite cohort of HIV-positive women. Am J Public Health. 2004;94(7):1133–40.

    Article  PubMed  Google Scholar 

  31. Rivas-Vazquez RA et al. A relationship-based care model for jail diversion. Psychiatr Serv. 2009;60(6):766–71.

    Article  PubMed  Google Scholar 

  32. Blankenship KM, Koester S. Criminal law, policing policy, and HIV risk in female street sex workers and injection drug users. J Law Med Ethics. 2002;30(4):548–59.

    Article  PubMed  Google Scholar 

  33. Petitt W, Western B. Mass imprisonment and the life course: race and class inequality in U.S. incarceration. Am Soc Rev. 2004;69:151–69.

    Article  Google Scholar 

  34. Hammett TM, Harmon MP, Rhodes W. The burden of infectious disease among inmates of and releasees from US correctional facilities, 1997. Am J Public Health. 2002;92(11):1789–94.

    Article  PubMed  Google Scholar 

  35. Jurgens R et al. Panel: rights of people in prison to HIV prevention, treatment and care. HIV AIDS Policy Law Rev. 2009;14(2):84–92.

    PubMed  Google Scholar 

  36. Jafa K et al. HIV transmission in a state prison system, 1988-2005. PLoS One. 2009;4(5):e5416.

    Article  PubMed  Google Scholar 

  37. Dolan K, Larney S. A review of HIV in prisons in Nepal. Kathmandu Univ Med J (KUMJ). 2009;7(28):351–4.

    CAS  Google Scholar 

  38. Hammett TM. HIV/AIDS and other infectious diseases among correctional inmates: transmission, burden, and an appropriate response. Am J Public Health. 2006;96(6):974–8.

    Article  PubMed  Google Scholar 

  39. Marks G et al. Meta-analysis of high-risk sexual behavior in persons aware and unaware they are infected with HIV in the United States: implications for HIV prevention programs. J Acquir Immune Defic Syndr. 2005;39(4):446–53.

    Article  PubMed  Google Scholar 

  40. Small W et al. The impact of incarceration upon adherence to HIV treatment among HIV-positive injection drug users: a qualitative study. AIDS Care. 2009;21(6):708–14.

    Article  PubMed  Google Scholar 

  41. Kinlock TW et al. A study of methadone maintenance for male prisoners: 3 month post-release outcomes. Crim Justice Behav. 2008;35(1):34–47.

    Article  PubMed  Google Scholar 

  42. ••Baillargeon J, et al. Accessing antiretroviral therapy followiong release from prison. JAMA 2009;301(8):848-57. This study of 2115 HIV-positive inmates in Texas found significant interruptions in ART following release from prison, with only 5% of subjects filling a subsidized prescription within 10 days of release and 30% filling it within 60 days of release. This interruption in treatment creates heightened risks for adverse clinical outcomes, reservoirs of drug-resistant HIV, and greater infectiousness.

    Article  PubMed  CAS  Google Scholar 

  43. Maru DS, Basu S, Altice FL. HIV control efforts should directly address incarceration. Lancet Infect Dis. 2007;7(9):568–9.

    Article  PubMed  Google Scholar 

  44. Khan MR, et al. Dissolution of primary intimate relationships during incarceration and associations with post-release STI/HIV risk behavior in a Southeastern City. Sex Transm Dis, 2010.

  45. Maruschak L. HIV in prisons, 2006, B.o.J.S. US Department of Justice, Editor. 2007.

  46. Dixon PS et al. Infection with the human immunodeficiency virus in prisoners: meeting the health care challenge. Am J Med. 1993;95(6):629–35.

    Article  PubMed  CAS  Google Scholar 

  47. Baillargeon J et al. Psychiatric disorders and suicide in the nation's largest state prison system. J Am Acad Psychiatry Law. 2009;37(2):188–93.

    PubMed  Google Scholar 

  48. Wakeman SE, McKinney ME, Rich JD. Filling the gap: the importance of Medicaid continuity for former inmates. J Gen Intern Med. 2009;24(7):860–2.

    Article  PubMed  Google Scholar 

  49. Zahari MM et al. Psychiatric and substance abuse comorbidity among HIV seropositive and HIV seronegative prisoners in Malaysia. Am J Drug Alcohol Abuse. 2010;36(1):31–8.

    Article  PubMed  Google Scholar 

  50. Stuckler D et al. Mass incarceration can explain population increases in TB and multidrug-resistant TB in European and central Asian countries. Proc Natl Acad Sci U S A. 2008;105(36):13280–5.

    Article  PubMed  CAS  Google Scholar 

  51. Podlekareva DN et al. Mortality from HIV and TB coinfections is higher in Eastern Europe than in Western Europe and Argentina. AIDS. 2009;23(18):2485–95.

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

This manuscript was supported by the Centers for AIDS Research (grants P30AI027757, P30AI027763, P30AI036211, P30AI028697, P30AI060354, P30AI050409, P30AI036219, P30AI027742, P30AI027767, P30AI064518, P30AI051519, P30AI045008, P30AI087714, P30AI082151, P30AI042853, P30AI054999, P30AI078498, P30AI050410, P30AI073961, P30AI036214, P30AI042845), as well as grants K24DA022112, K23DA029381, K24DA017072, R01DA025943, R01DA25932, R01DA017059, R01DA029910, R01DA030762, R01DA030768, R01DA030762, R01DA18641, R01DA030778, R01DA027211, and R01DA027211 from the National Institute on Drug Abuse, National Institutes of Health, and R01AA018944 from the National Institute on Alcohol Abuse and Alcoholism at the National Institutes of Health. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute on Drug Abuse or the National Institutes of Health.

Disclosure

J. D. Rich: none; D. A. Wohl: none; C. G. Beckwith: none; A. Spaulding: none; N. E. Lepp: none; J. Baillargeon: expert testimony for UTMB/CMC; A. Gardner: none; A. Avery: none; F. L. Altice: speakers’ bureau for BMS, Genentech, Tibotec, Simply Speaking, and ViralEd; S. Springer: none.

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Correspondence to Josiah D. Rich.

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CFAR-CHIC working group members and affiliations

Judith Aberg, MD (NYU), Julie Adams (Duke), Frances Aunon (Duke), Sameena Azhar, MSW, MPH (UCSF), David Bebinger, MD (UMass), Kim Blankenship, PhD (Duke), Amy Boutwell, MD (Harvard), Brad Brockmann, JD (Brown), Laurence Brown, MD (Brown), Douglas Bruce, MD, MA, MSc (Yale), Christopher Cannon, MPH (Yale), Holly Cassell, MPH (Vanderbilt), Charles Carpenter, MD (Brown), Jennifer Clarke, MD (Brown), Myron Cohen, MD (UNC), Megan Comfort, PhD (UCSF), Karen Cropsey, PsyD (UAB), Michael Costa (Abt Associates), Gabriel Culbert, RN, BSN (UIC), William Cunningham, MD, MPH (UCLA), Jennifer Daly, MD (UMass), Richard D’Aquila, MD (Vanderbilt), Raul Davaro, MD (UMass), Nancy DeSousa, MPH (Emory), Andrew Desruisseau, MD (Meharry Medical College), Stephen Dewhurst, PhD (University of Rochester), Samuel Dickman, AB (Brown), Ralph Diclemente, PhD (Emory), Geri Donenberg, PhD (UIC), Jeff Draine, PhD (University of Pennsylvania), Dora Dumont, PhD, MPH (Brown), Warren Ferguson, MD (UMass), Michael Fine, MD (RI DOC), Margaret Fischl, MD (University of Miami), Patrick Flynn, PhD (TCU), Peter Friedmann, MD, MPH (Brown), Becky Genberg, PhD (Brown), Toorjo Ghose, MSW, PhD (UPenn), Thomas P. Giordano, MD, MPH (Baylor), Carol Golin, MD (UNC), Michael Gordon, DPH (Friends Research), Traci Green, PhD (Brown), Richard M. Grimes, PhD (Baylor/UT Houston), Kimberly Hagen, MeD, EdD (Emory), Connie Haley, MD, MPH (Vanderbilt), Theodore Hammett, PhD (Abt Associates), Clemens Hong, MD (Harvard), Diana Huang, PhD (Rush), Martin Iguchi, PhD (UCLA/RAND), Michael Keefer, MD (University of Rochester), Arthur Kim, MD (Harvard), Seijoung Kim, PhD (UIC), Timothy Kinlock, PhD (Friends Research), Kevin Knight, PhD (TCU), P. Todd Korthuis, MD, MPH (OHSU), Christopher Krebs, PhD (RTI International), Alexander Kral, PhD (UCSF), Sonali Kulkarni, MD, MPH (UCLA), Irene Kuo, MPH, PhD (George Washington), Ann Kurth, PhD, CNM (NYU), Teaniese Latham, MPH, (Emory), Daniel Lee, MD (UCSD), Joshua Lee, MD, MSc (NYU), Jennifer Lorvick, MPH (RTI International), Paula Lum, MD, MPH (UCSF), Karen Lyda, LCSW, MS, NP (University of Colorado Denver), Thomas Lyons, PhD (UIC), Mark Malek, MD, MPH (LASD), Eileen Martin, PhD (UIC), Rosemarie Martin, PhD (Brown), Christopher Mathews, MD, MSPH (UCSD), Barbara McGovern, MD (Tufts), Michelle McKenzie, MPH (Brown), Jennifer McNeely, MD, MS (NYU), Gerald Melnick, PhD (NDRI), Lisa Metsch, PhD (University of Miami), Jennifer Mitty, MD, MPH (Harvard), Brian Montague, DO (Brown), Michael Mugavero, MD, MHSc (UAB), Janet Myers, PhD, MPH (UCSF), Ank Nijhawan, MD, MPH (Harvard), Amy Nunn, ScD (Brown), David Ostrow, MD, PhD (University of Chicago), Lawrence Ouellet, PhD (UIC), David Paar, MD (UTMB), Wilson R. Palacios, PhD (University of South Florida), James Peterson, PhD (GWU), Steven Pinkerton, MD (MCW), Robin Pollini, PhD, MPH (UCSD), Michael Puisis, DO (Cermak Health Services), Han-zhu Qian, MD, PhD (Vanderbilt), Vu Minh Quan, MD (Johns Hopkins), David Rosen, PhD (UNC), Michael W. Ross, PhD, MA, MS (University of Texas), Monica Ruiz, PhD, MPH (GWU), Jennifer Sayles, MD, MPH (LA County Department of Public Health), Joseph Schumacher, PhD (UAB), David Wyatt Seal, PhD (Medical College of Wisconsin), Jane Simoni, PhD (UW), Liza Solomon, PhD (Abt Associates), James Sosman, MD (University of Wisconsin), Lara Strick, MD, MSc (University of Washington), David Stone, MD (Tufts), Patrick Sullivan, PhD (Emory), Faye Taxman, PhD (George Mason), Lynn E. Taylor, MD (Brown), Marina Tolou-Shams, PhD (Brown), Jacqueline Tulsky, MD (UCSF), Homer Venters, MD, MS (NYU), Sten Vermund, PhD (Vanderbilt), Sarah Wakeman, MD (Harvard), Emily Wang, MD, MAS (Yale), Carolyn Wester, MD, MPH (Tennessee Department of Health), Ryan Westergaard, MD (Johns Hopkins), Becky L. White, MD, MPH (UNC), Chyvette Williams, PhD (UIC), Gina Wingood (Emory), Samantha Yard (UW), Jeremy D. Young, MD, MPH (UIC), Barry Zack, MPH (Bridging Group), Nickolas Zaller, PhD (Brown), Chad Zawitz, MD (Cook County Jail)

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Rich, J.D., Wohl, D.A., Beckwith, C.G. et al. HIV-Related Research in Correctional Populations: Now is the Time. Curr HIV/AIDS Rep 8, 288–296 (2011). https://doi.org/10.1007/s11904-011-0095-3

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