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Two-dimensional separations and behaviour of alkaloids of various polarities on unmodified silica gel in polar and very polar neutral or acidic mobile phases

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Summary

New separation procedures for alkaloids of similar polarity and structure or of very different polarity and structure, based upon two-dimensional thin-layer chromatography on unmodified silica gel under mild conditions are described. Separation factors and separation mechanisms based on the structure of the bases and mobile phase composition are discussed for some examples of very efficient procedures.

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Authors and Affiliations

  1. C.N.R.S., Institut Pasteur, 28, rue du Docteur Roux, Cedex 15, F-75724, France

    R. L. Munier & S. Meunier

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  1. R. L. Munier
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  2. S. Meunier
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Proportions in solvent mixtures are v/v except where otherwise indicated.

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Munier, R.L., Meunier, S. Two-dimensional separations and behaviour of alkaloids of various polarities on unmodified silica gel in polar and very polar neutral or acidic mobile phases. Chromatographia 13, 259–262 (1980). https://doi.org/10.1007/BF02265638

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  • DOI: https://doi.org/10.1007/BF02265638

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