Abstract
Idiopathic hypogonadotropic hypogonadism (IHH) and Kallmann syndrome (Kallmann et al. 1944) are closely related diseases sharing disturbed hypothalamic secretion of GnRH as their core pathophysiological feature Hypogonadism resulting from the GnRH deficiency is the only clinical manifestation of idiopathic hypogonadotropic hypogonadism. In addition, patients with Kallmann syndrome feature anosmia and occasionally some other physical anomalies.
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Behre, H.M., Nieschlag, E., Meschede, D., Partsch, C.J. (2001). Diseases of the Hypothalamus and the Pituitary Gland. In: Nieschlag, E., Behre, H.M. (eds) Andrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-04491-9_7
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