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Principles of Vascular Physiology

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Pan Vascular Medicine

Abstract

The basis of modern cardiovascular hemodynamics was established in the 1960s and 1970s. Invasive measurements of aortic pressure and flow in mammals and humans demonstrated that the cardiac pulsation generates pressure and flow waves, traveling along the arterial tree. Arterial pressure and flow were studied as wave phenomena and it was realized that relevant, quantitative hemodynamic assessment of the cardiovascular system required measurement of both pressure and flow. The concept of arterial impedance was introduced. Wave reflection was found to be an important determinant of the pressure and flow wave contours, altering with age, in cardiovascular disease or in response to drugs.

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  1. Patrick Segers
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  2. Pascal Verdonck
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Editors and Affiliations

  1. Herz-Zentrum Coswig, Klinik für Kardiologie und Angiologie, Lerchenfeld 1, 06869, Coswig (Anhalt), Germany

    Peter Lanzer MD

  2. The Cleveland Clinic Foundation, One Clinic Center, 9500 Euclid Avenue, Cleveland, 44195, OH, USA

    Eric J. Topol MD

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© 2002 Springer-Verlag Berlin Heidelberg

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Segers, P., Verdonck, P. (2002). Principles of Vascular Physiology. In: Lanzer, P., Topol, E.J. (eds) Pan Vascular Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56225-9_6

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  • DOI: https://doi.org/10.1007/978-3-642-56225-9_6

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