Abstract
The presence of renal calculi in humans has been identified in mummies discovered as long ago as 4,000 bc, affecting humans for millennia. The underlying aetiology of both nephrocalcinosis and nephrolithiasis is complex. An appreciation of the processes involved in calculus formation aids in the understanding of the diagnosis and management of the disease. The progression of imaging technology has promoted increasingly sensitive and specific techniques in the diagnosis of nephrocalcinosis and nephrolithiasis. Currently, non-contrasted computed tomography has superceded the excretory intravenous urogram in the investigation of acute renal colic because of diagnostic accuracy and ease of application. An understanding of current imaging technology and techniques is necessary to allow its appropriate application in the diagnosis and ongoing management of nephrocalcinosis and nephrolithiasis.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Amis ES Jr (1999) Epitaph for the urogram. Radiology 213: 639–640
Asplin JR, Favus MJ, Coe FL (1996) Nephrolithiasis. In: Brenner BM (ed) The kidney. WB Saunders, Philadelphia, PA, pp 1893–1935
Blake SP, McNicholas MM, Raptopoulos V (1998) Non opaque crystal deposition causing ureteric obstruction in patients with HIV undergoing indinavir therapy. AJR 171:717–720
Boll DT, Patil NA, Paulson EK et al. (2009) Renal stone assessment with dual-energy multidetector CT and advanced postprocessing techniques: improved characterization of renal stone composition – pilot study. Radiology 250:813–820
Boridy IC, Kawashima A, Goldman SM et al. (1999) Acute ureteolithiasis: nonenhanced helical CT findings of perinephric oedema for prediction of degree of ureteral obstruction. Radiology 213:663–667
Burge HJ, Middleton WD, McClennan BL et al. (1991) Ureteral jets in healthy subjects and in patients with unilateral ureteral calculi: comparison with color Doppler US. Radiology 180(2):437–442
Campbell SC, Cullinnan JA, Rubens DJ (2004) Slow flow or no flow? Color and power Doppler US pitfalls in the abdomen and pelvis. Radiographics 28:497–506
Cox IH, Erickson SJ, Foley WD et al. (1992) Ureteric jets: evaluation of normal flow dynamics with color Doppler sonography. AJR 158:1051–1055
Dalla Palma L, Pozzi-Mucelli R, Stacul F (2001) Present-day imaging of patients with renal colic. Eur Radiol 11:4–17
Dalla Palma L, Stacul F, Bazzocchi M et al. (1993) Ultrasonography and plain film versus intravenous urography in ureteric colic. Clin Radiol 47(5):333–336
Deveci S, Co kun M, Tekin M et al. (2004) Spiral computed tomography: role in determination of chemical compositions of pure and mixed urinary stones-an in vitro study. Urology 64:237–240
Fan J, Chandhoke PS, Grampas SA (1999) Role of sex hormones in experimental calcium oxalate nephrolithiasis. J Am Soc Nephrol 10:S376–S380
Fowler KA, Locken JA, Duchesne JH et al. (2002) US for detecting renal calculi with nonenhanced CT as a reference standard. Radiology 222:109–113
Freeman SJ, Sells S (2008) Investigation of loin pain. Imaging 20:38–56
Georgiades CS, Moore CJ, Smith DP (2001) Differences of renal parenchymal attenuation for acutely obstructed and unobstructed kidneys on unenhanced helical CT: a useful secondary sign? AJR 175:325–330
Girish G, Chooi WK, Morocos SK (2004) Filling defect artefacts in magnetic resonance urography. Eur Rad 14:145–150
Gleeson MJ, Griffith DP (1993) Struvite calculi. Br J Urol 71:503–511
Goldman SM, Faintuch S, Ajzen SA et al. (2004) Diagnostic value of attenuation measurements of the kidney on unenhanced helical CT of obstructive ureteolithiasis. AJR 182:1251–1254
Grosjean R, Sauer B, Guerra RM et al. (2008) Characterization of human renal stones with MDCT: advantage of dual energy and limitations due to respiratory motion. AJR 190:720–728
Haddad MC, Sharif HS, Abomelha MA et al. (1994) Colour Doppler sonography and plain abdominal radiography in the management of patients with renal colic. Eur Radiol 4: 529–532
Haddad MC, Sharif HS, Shahed MS et al. (1992) Renal colic: diagnosis and outcome. Radiology 184:83–88
Hamm M, Knopfle E, Wartenberg S et al. (2002) Low dose unenhanced helical computerized tomography for the evaluation of acute flank pain. J Urol 167:1687–1691
Hillman BJ, Drach GW, Tracey P et al. (1984) Computed tomographic analysis of renal calculi. AJR 142:549–552
Joseph P, Mandal AK, Singh KL et al. (2002) Computerized tomography attenuation value of renal calculus: can it predict successful fragmentation of the calculus by extracorporeal shock wave lithotripsy? A preliminary study. J Urol 167:1968–1971
Kennish SJ, Bhatnagar P, Wah TM et al. (2008) Is the KUB radiograph redundant for investigating acute ureteric colic in the non-contrast enhanced computed tomography era? Clin Radiol 63:1131–1135
Kluner C, Hein PA, Gralla O et al. (2006) Does ultra-low-dose CT with a radiation dose equivalent to that of KUB suffice to detect renal and ureteral calculi? J Comput Assist Tomogr 30(1):44–50
Knöpfle E, Hamm M, Wartenberg S et al. (2003) CT in ureterolithiasis with a radiation dose equal to intravenous urography: results in 209 patients. Rofo 175(12):1667–1672
Levine J, Neitlich J, Smith RC (1999) The value of prone scanning to distinguish ureterovesical junction stones from ureteral stones that have passed into the bladder: leave no stone unturned. AJR 172:977–981
Mahesh M, Scatarige JC, Cooper J et al. (2001) Dose and pitch relationship for a particular multislice CT scanner. AJR 177(6):1273–1275
McLeod RD, Churchill DN (1992) Urolithiasis complicating inflammatory bowel disease. J Urol 148:974–978
Meagher T, Sukmar VP, Collingwodd J et al. (2001) Low dose computed tomography in suspected acute colic. Clin Radiol 56:873–876
Memarsadeghi M, Heinz-Peer G, Schaefer-Prokop et al. (2005) Unenhanced multi-detector row CT in patients suspected of having urinary stone disease: effect of section width on diagnosis. Radiology 235:530–536
Menon M, Resnick MI (2002) Urinary lithiasis: etiology, diagnosis, and medical management. In: Walsh PC, Retik AB, Darracott VE Jr (eds) Campbell’s urology. WB Saunders, Philadelphia, PA, pp 3229–3305
Michaels EK, Nakagawa Y, Miura N et al. (1994) Racial gender variation in gender frequency of calcium urolithiasis. J Urol 152:2228–2231
Middleton WD, Dodds WJ, Lawson TL et al. (1988) Renal calculi: sensitivity for detection with US. Radiology 167:239–244
Miller OF, Kane CJ (2000) Unenhanced helical computed tomography in the evaluation of acute flank pain. Curr Opin Urol 10:123–129
Mortensen JD, Emmett JL (1954) Nephrocalcinosis: a collective and clinicopathological study. J Urol 71:398–406
Nakada SY, Douglas GH, Attai S et al. (2000) Determination of stone composition by noncontrast spiral computed tomography in the clinical setting. Urology 55:816–819
Nawfel RD, Judy PF, Schleipman AR et al. (2004) Patient radiation dose at CT urography and conventional urography. Radiology 232:126–132
Niall O, Russell J, MacGregor R et al. (1999) A comparison of noncontrast computerized tomography with excretory urography in the assessment of acute flank pain. J Urol 161(2):534–537
Ozdemir H, Demir MK, Temizöz O et al. (2008) Phase inversion harmonic imaging improves assessment of renal calculi: a comparison with fundamental gray-scale sonography. J Clin Ultrasound 36(1):16–19
Patel U, Walkden RM, Ghani KR et al. (2009) Three-dimensional CT pyelography for planning of percutaneous nephrostolithotomy: accuracy of stone measurement, stone depiction and pelvicalyceal reconstruction. Eur Radiol 19:1280–1288
Pfister SA, Deckaret A, Laschke S et al. (2003) Unenhanced helical computed tomography vs intravenous urography in patients with acute flank pain:accuracy and economic impact in a randomized prospective trial. Eur Radiol 13:2513–2520
Platt JF (1992) Duplex Doppler evaluation of native kidney dysfunction. Obstructive and nonobstructive disease. AJR 158: 1035–1042
Platt JF (1996) Urinary obstruction. Radiol Clin North Am 34:1113–1129
Platt JF, Rubin JM, Ellis JH (1989a) Distinction between obstructive and non obstructive pyelocaliectasis with Duplex Doppler sonography. AJR 153:997–1000
Platt JF, Rubin JM, Ellis JH et al. (1989b) Duplex Doppler US of the kidney: differentiation of obstructive and nonobstructive dilatation. Radiology 171:515–517
Platt JF, Rubin JM, Ellis JH (1993) Acute renal obstruction: evaluation with intrarenal duplex Doppler and conventional US. Radiology 186:685–688
Ramello A, Vitale C, Marangella M (2000) Epidemiology of nephrolithiasis. J Nephrol 13(suppl 3):S65–S70
Rivers K, Shetty S, Menon M (2000) When and how to evaluate a patient with nephrolithiasis. Urol Clin North Am 27:203–213
Rucker CR, Menias CO, Bhalla S (2004) Mimics of renal colic: alternative diagnoses at unenhanced helical CT. Radiographics 27:S11–S28
Sandhu C, Anson KM, Patel U (2003) Urinary tract stones – part I: role of radiological imaging in diagnosis and treatment planning. Clin Radiol 58:415–421
Saw KC, McAteer JA, Monga AG et al. (2000) Helical CT of urinary calculi: effect of stone composition, stone size, and scan collimation. AJR 175:329–332
Scales CD, Curtis LH, Norris R et al. (2007) Changing gender prevalence of stone disease. J Urol 177:979–982
Scheffel H, Stolzman P, Frauenfelder T et al. (2007) Dual-energy contrast-enhanced computed tomography for the detection of urinary stone disease. Invest Radiol 42:823–829
Schwartz B, Schenkman N, Armenakas N et al. (1999) Imaging characteristics of indinavir calculi. J Urol 161:1085–1087
Segal AJ, Spataro RF, Linke CA et al. (1978) Diagnosis of nonopaque calculi by computed tomography. Radiology 129: 447–450
Segura JW, Preminger GM, Assimos DG et al. (1997) Ureteral Stones Clinical Guidelines Panel summary report on the management of ureteral calculi. J Urol 158:1915–1921
Silverman SG, Leyendecker JR, Amis ES Jr (2009) What is the current role of CT urography and MR urography in the evaluation of the urinary tract? Radiology 250:309–323
Smith RC, Rosenfield AT, Choe KA et al. (1995) Acute flank pain: comparison of non-contrasted CT and intravenous urography. Radiology 194:789–794
Smith RC, Verga M, Dalrymple N et al. (1996) Acute ureteral obstruction: value of secondary signs of helical unenhanced CT. AJR 167(5):1109–1113
Sourtzis S, Thibeau JF, Damry N et al. (1999) Radiologic investigation of renal colic: unenhanced helical CT compared with excretory urography. AJR 172(6):1491–1494
Spirnak JP, Resnick MI, Banner MP (1990) Calculus disease of the urinary tract. In Davidson AJ, Hartman D (eds) Radiology of the kidney and urinary tract. WB Saunders, Philadelphia, PA, pp 53–96
Svedström E, Alanen A, Nurmi M (1990) Radiologic diagnosis of renal colic: the role of plain film, excretory urography and sonography. Eur J Radiol 11(3):180–183
Tack D, Sourtzis S, Dellpierre I et al. (2003) Low dose multidetector CT of patients with suspected renal colic. AJR 180:305–311
Taourel P, Thuret R, Hoquet MD et al. (2008) Computed tomography in the nontraumatic renal causes of acute flank pain. Semin Ultrasound CT MRI 29:341–352
Tchelepi H, Ralls PW (2009) Color comet-tail artifact: clinical applications. AJR 192:11–18
Teichman JMH (2004) Acute renal colic from ureteral calculus. N Engl J Med 350:684–693
Thomas C, Patschan O, Ketelsen D et al. (2009) Dual-energy CT for the characterization of urinary calculi: in vitro and in vivo evaluation of a low-dose scanning protocol. Eur Radiol 19:1553–1559
Townsend BA, Silverman SG, Mortele KJ et al. (2009) Current use of computed tomographic urography: survey of the Society of Uroradiology. J Comput Assist Tomogr 33: 96–100
Traubici J, Neitlich JD, Smith RC (1999) Distinguishing pelvic phleboliths from distal ureteral stones on routine unenhanced helical CT: is there a radiolucent center? AJR 172:13–17
Wrong OM, Feest TG (1976) Nephrocalcinosis. In: Peters DK (ed) Advanced medicine no 12. Pitman Medical, London, pp 394–206
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer Berlin Heidelberg
About this chapter
Cite this chapter
Phillips, S., Tudor, G.R. (2010). Nephrocalcinosis and Nephrolithiasis. In: Quaia, E. (eds) Radiological Imaging of the Kidney. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-87597-0_15
Download citation
DOI: https://doi.org/10.1007/978-3-540-87597-0_15
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-87596-3
Online ISBN: 978-3-540-87597-0
eBook Packages: MedicineMedicine (R0)