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The Subpial Granular Layer in the Developing Cerebral Cortex of Rodents

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Mouse Brain Development

Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 30))

Abstract

The subpial granular layer (SGL) is a transient layer of small, undifferentiated cells located immediately below the pial surface of the cerebral cortex. It was first described by Ranke (1910) in the marginal zone (MZ), the prospective cortical layer I, of human fetuses around midgestation. While Ranke believed the SGL to be composed mainly of glia, other authors such as Schaffer (1918) and Brun (1965) considered it a predominantly neuronal structure. The neuronal character of most of its constituent cells was later confirmed by Gadisseux et al. (1992) by using immunocytochemistry with neuron-specific antibodies.

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Author information

Authors and Affiliations

  1. Departamento de Anatomía, Facultad de Medicina, Universidad de La Laguna, 38071, La Laguna, Tenerife, Spain

    Gundela Meyer

  2. Departamento de Fisiología, Facultad de Medicina, Universidad de La Laguna, 38071, La Laguna, Tenerife, Spain

    Rafael Castro

  3. Instituto de Neurociencias, CSIC, Universidad Miguel Hernandez, 03550, San Juan de Alicante, Spain

    José Miguel Soria & Alfonso Fairén

Authors
  1. Gundela Meyer
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  2. Rafael Castro
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  3. José Miguel Soria
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  4. Alfonso Fairén
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Editor information

Editors and Affiliations

  1. Neurobiology Unit, University of Namur Medical School, 61, rue de Bruxelles, B-5000, Namur, Belgium

    André M. Goffinet

  2. Section of Neurobiology, Yale University School of Medicine, 333, Cedar Street, 06510, New Haven, CT, USA

    Pasko Rakic

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© 2000 Springer-Verlag Berlin Heidelberg

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Meyer, G., Castro, R., Soria, J.M., Fairén, A. (2000). The Subpial Granular Layer in the Developing Cerebral Cortex of Rodents. In: Goffinet, A.M., Rakic, P. (eds) Mouse Brain Development. Results and Problems in Cell Differentiation, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-48002-0_12

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  • DOI: https://doi.org/10.1007/978-3-540-48002-0_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-53684-7

  • Online ISBN: 978-3-540-48002-0

  • eBook Packages: Springer Book Archive

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