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Pudendal Neuralgia

Pudendal Nerve Entrapment, Alcock Canal Syndrome, and Pudendal Canal Syndrome

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Genitourinary Pain And Inflammation

Part of the book series: Current Clinical Urology ((CCU))

Summary

Pudendal neuralgia is a peripheral neuropathy of the pudendal nerve, generally due to compression between the sacrotuberous and sacrospinous ligaments. It is a tunnel syndrome. We have treated persons of both genders between 14 and 87 years of age. The characteristic symptoms are pelvic pains that are aggravated by sitting and driving and reduced by sitting on a toilet seat. Bowel, bladder, and sexual dysfunctions are common. The diagnosis is confirmed at physical examination of the pudendal sensory nerves. Objective neurophysiological tests include quantitative sensory testing of warm detection threshold and the pudendal nerve terminal motor latency test. Pudendal neuralgia is caused by repetitive flexion of the hip as in exercise and athletics, childbirth, sitting, and cycling. Treatment of pudendal neuralgia is analogous to treatment of the carpal tunnel syndrome. Nerve damage is prevented by a self-care protection program. When necessary, pudendal nerve perineural injection (PNPI) of local anesthesia and corticosteroids is necessary. Thirty percent or more patients require decompression surgery of the pudendal nerves. Each of these sequential treatments can provide prolonged relief of more than 5 years.

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References

  1. Hilton J. Rest and Pain. London: G. Bell and Sons, 5th ed;1918:244.

    Google Scholar 

  2. Robert R, Prat-pradat D, Labat JJ, et al. Anatomic basis of chronic perineal pain: role of the pudendal nerve. Surg Radiol Anat 1998;20:93–98.

    Article  PubMed  CAS  Google Scholar 

  3. Bascom J. Pelvic pain. Perspectives in Colon and Rect Surg. 1999;11:21–40. Peterson N. Genitoperineal injury induces by orthopedic fracture table. J Urol 1985;134:760–761.

    Google Scholar 

  4. Benson JT, Griffis K. Pudendal neuralgia, a severe pain syndrome. Am J Obstet Gynecol 2005;192(5):1663–1668.

    Article  PubMed  Google Scholar 

  5. Amarenco G, Lanoe Y, Perrigot M, Goudal H. Un nouveau syndrome canalaire: la compression du nerf honteux interne dans le canal d’Alcock ou paralysie pe’rine’ale du cycliste. La Presse Medicale 1987;160:399.

    Google Scholar 

  6. Shafik A. Pudendal canal syndrome: a new etiological factor in prostadynia and its treatment by pudendal canal [de]compression. Pain Digest 1998;8:32–36.

    Google Scholar 

  7. Roberts RO, Lieber MM, Bostwick DG, et al. A review of clinical and pathological prostatitis syndromes. Urology 1997;49:809–821.

    Article  PubMed  CAS  Google Scholar 

  8. Nickel JC, Downey J, Hunter D, Clark J. Prevalence of prostatitis-like symptoms in a population-based study using the National Institutes of Health chronic prostatitis symptom index. J Urol 2001;163:842–845.

    Google Scholar 

  9. Mahakanukrauh P. Anatomical study of the pudendal nerve adjacent to the sacrospinous ligament. Clin Anat 2005;18:200–205.

    Article  Google Scholar 

  10. Nakanishi T. Studies on the pudendal nerve. I. A macroscopical observation of the pudendal nerve in man. Kaibogaku Zasshi (Acta Anat Jap) 1967;42:223–239 (Original in Japanese).

    CAS  Google Scholar 

  11. Gruber H, Kovacs P, Peigger J, Brenner E. New, simple ultrasound-guided infiltration of the pudendal nerve: topographic basics. Dis Colon Rectum 2001;44:1376–1380.

    Article  PubMed  CAS  Google Scholar 

  12. Woolf CJ, Mannion RJ. Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet 1999;353:1959–1964.

    Article  PubMed  CAS  Google Scholar 

  13. Amarenco G, Kerdraon J, et al. Efficacity and safety of different treatments of perineal neuralgia due to compression of the pudendal nerve within the ischio-rectal fossa or by ischiatic spine. Revue Neurologique 1997;153:331–334.

    PubMed  CAS  Google Scholar 

  14. Silbert PL, Dunne JW, Edis RH, Stewart-Wynne EG. Bicycling-induced pudendal nerve pressure neuropathy. Clin Exp Neurol 1991;28:191.

    PubMed  CAS  Google Scholar 

  15. Weiss BD. Clinical syndromes associated with bicycle seats. Clin Sports Med 1994;13:175–186.

    PubMed  CAS  Google Scholar 

  16. Anderson KV and Bovim G. Impotence and nerve entrapment in long-distance amateur cyclists. Acta Neurol Scand 1997;95:233–240.

    Google Scholar 

  17. Peterson NE. Genitoperineal injury induced by orthopaedic fracture table. J Urol 1985;134:760–761.

    PubMed  CAS  Google Scholar 

  18. Brumback RJ, Ellison TS, et al. Pudendal nerve palsy complicating intramedullary nailing of the femur. J Bone Joint Surgery 1992;74-A, No. 10 December.

    Google Scholar 

  19. Mallet R, Tricoire J-L, Rischman P, Sarramon JP, Pugel J, Malavaud B. High prevalence of erectile dysfunction in young male patients after intramedullary femoral nailing. Urology 2005;65:559–563.

    Article  PubMed  Google Scholar 

  20. Allen RE, Hosker GL, Smith ARB, Warrell DW. Pelvic floor damage and childbirth: a neuropysiological study. Br J Obstet Gynaecol 1990;97:770–779.

    PubMed  CAS  Google Scholar 

  21. Snooks SJ, Swash M. Abnormalities of the innervation of the urethral striated sphincter musculature in incontinence. Br J Urol 1984;56:410–415.

    Google Scholar 

  22. Tetzschner T, Sorensen M, Lose G, Christiansen J. Pudendal nerve function during pregnancy and after delivery. Int Urogynecol J Pelvic Floor Dysfunct 1997;8:66–68.

    Article  PubMed  CAS  Google Scholar 

  23. Shafik A. Levator ani muscle: new physioanatomical aspects and role in the micturition mechanism. World J Urol 1997;17:266.

    Article  Google Scholar 

  24. Sultan AH, Kamm MA Hudson CN. Pudendal nerve damage during labour: prospective study before and after childbirth. Br J Obstet Gynaecol 1994;101:22–28.

    PubMed  CAS  Google Scholar 

  25. Antolak S, Hough D, Pawlina W, Spinner R. Anatomical basis of chronic pelvic pain syndrome: the ischial spine and pudendal nerve entrapment. Med Hypotheses 2002;59:349.

    Article  PubMed  Google Scholar 

  26. Rabon LD. Chronic Pelvic pain syndrome…an occupational and/or recreational hazard. Presentation. International Prostatitis Collaborative Network, sponsored by the National Institutes of Health. Washington DC, October 23–25, 2000.

    Google Scholar 

  27. Bautrant E, de Bisschop E, Vaini-Elies V, et al. Modern algorithms for treating pudendal neuralgia; 2122 cases and 104 decompressions. J Gynecol Obstet Biol Reprod (Paris) 2003;32:705–712.

    CAS  Google Scholar 

  28. Alevizon SJ, Finan MA. Sacrospinous colpopexy: management of pudendal nerve entrapment. Obstet Gynecol 1996;88:713–715.

    Article  PubMed  CAS  Google Scholar 

  29. Benson JT, McClellan E. The effect of vaginal dissection on the pudendal nerve. Obstet Gynecol 1993;82:387–389.

    PubMed  CAS  Google Scholar 

  30. Shembalkar P, Anand P, Junaid I, Fowler C, Wlliams NS. Neuropathic pain with vesical and rectal hyperreflexia and cocontraction after pelvic surgery. J Neurol Neurosurg Psychiatry 2001;70:410–411.

    Article  PubMed  CAS  Google Scholar 

  31. Antolak SJ, Hough DM, Pawlina W. The chronic pelvic pain syndrome after brachytherapy for carcinoma of the prostate. J Urol 2002;167:2525.

    Article  PubMed  Google Scholar 

  32. Shafik A. Chronic scrotalgia: report of four cases with successful treatment. Pain Digest 1993;3:252–256.

    Google Scholar 

  33. Ali-el-dein B, Ghoneim MA. Effects of selective autonomic and pudendal denervation on the urethral function and development of retention in female dogs. J Urol 2001;166:1549–1554.

    Article  PubMed  CAS  Google Scholar 

  34. Diokono AC, Homma Y, et al. Interstitial cystitis, gynecologic pelvic pain, prostatitis, and their epidemiology. Int J Urol 2003;10:S3.

    Article  Google Scholar 

  35. Byrne PJ, Quill R, Keeling PWN. Pudendal nerve neuropathies are extremely common in chronic constipation and faecal incontinence. Gastroenterology 1998;114 Suppl S.

    Google Scholar 

  36. Kiff ES, Swash M. Normal proximal and delayed distal conduction in the pudendal nerves of patients with idiopathic (neurogenic) faecal incontinence. J Neurol Neurosurg Psychiatry 1984;47:820–832.

    Article  PubMed  CAS  Google Scholar 

  37. Shafik A. Stress urinary incontinence: an alternative concept of pathogenesis. Int Urogynecol J Pelvic Floor Dysfunct 1994;5:3.

    Google Scholar 

  38. Curtis P. In Search of the ‘Back Mouse.’ J Fam Pract 1993;36:657–659.

    PubMed  CAS  Google Scholar 

  39. Wright ET, Chmiel JS, Grayhack JT, Schaeffer AJ. Prostatic fluid inflammation in prostatitis. J Urol 1994;152:2300–2303.

    PubMed  CAS  Google Scholar 

  40. Ludwig M, Schroeder-Printzen I, Ludecke G, Weidner W. Comparison of Expressed Prostatic Secretions with urine after prostatic massage—a means to diagnose chronic prostatitis/inflammatory chronic pelvic pain syndrome. Urology 2000;55:175–177.

    Article  PubMed  CAS  Google Scholar 

  41. Amarenco G, Ismael SS, Bayle B, Denys P, Kerdraon J. Electrophysiological analysis of pudendal neuropathy following traction. Muscle Nerve 2001;24:116–119.

    Article  PubMed  CAS  Google Scholar 

  42. Vodusek DB, Light JK, Libby JM. Detrusor inhibition induced by stimulation of pudendal nerve afferents. Neurourol Urodyn 1986;5:381.

    Article  Google Scholar 

  43. Ricchiutu VS, Haas CA, Seftel AD, et al. Pudendal nerve injury associated with avid bicycling. J Urol 2000;162:2099–2100.

    Article  Google Scholar 

  44. Benson JT. Electrodiagnosis in pelvic floor neuropathy. In: Benson JT, ed. Investigation and Management of Female Pelvic Floor Disorder. New York: Norton Medical Books. 1992:157–165.

    Google Scholar 

  45. Welgoss JA, Vogt VY, McClellan EJ, Benson JT. Relations between surgically induced neuropathy and outcome of pelvic organ prolapse surgery. J Int Urogynecol 1999;10:11–14.

    Article  CAS  Google Scholar 

  46. Olsen AL, Ross M, Stansfield RB, Kreiter C. Pelvic floor nerve conduction studies: establishing clinically relevant normative data. Am J Obstet Gynecol 2003;189:1114–1119.

    Article  PubMed  Google Scholar 

  47. Bleustein CB, Eckholdt E, Arezzo JC. Quantitative somatosensory testing of the penis: optimizing the clinical neurological examination. J Urol 2003;169:2266–2269.

    Article  PubMed  Google Scholar 

  48. Antolak CM, Antolak SJ. Midline warm detection threshold evaluation for impotence is inaccurate. Poster presented at North Central Section American Urological Association Annual Meeting; September 7–10, 2005. Chicago, IL. Abstract p. 480.

    Google Scholar 

  49. Lee JC, Yang CC, Kromm BG, Berger RE. Neurophysiologic testing in chronic pelvic pain syndrome: a pilot study. Urology 58(2), 2001.

    Google Scholar 

  50. Dyck PJ, O’Brien PC, Kosanke JL, Gillen DA, Karnes JL. A 4, 2, and 1 stepping algorithm for quick and accurate estimation of cutaneous sensation threshold. Neurology 1993;43:1508–1512.

    PubMed  CAS  Google Scholar 

  51. Filler AG, Maravilla KR, Tsuruda JS. MR neurography and muscle imaging for image diagnosis of disorders affecting the peripheral nerves and musculature. Neurol Clin 2004;22:643–682.

    Article  PubMed  Google Scholar 

  52. Bensignor MF, Labat JJ, Robert R, and Ducrot P. Diagnostic and therapeutic nerve blocks for patients with perineal non-malignant pain. Abstract, 8th World Congress on Pain. 1996:56.

    Google Scholar 

  53. Shafik A, El-sherif M, Youseff A, Olfat E. Surgical anatomy of the pudendal nerve and its clinical implications. Clin Anat 1998;8:110–115.

    Article  Google Scholar 

  54. Bors E, Comarr E, Moulton SH. The role of nerve blocks in management of traumatic cord bladders: spinal anesthesia, subarachnoid alcohol injections, pudendal nerve anesthesia and vesical neck anesthesia. J Urol 1950;63:653–666.

    PubMed  CAS  Google Scholar 

  55. Schmidt RA. Technique of pudendal nerve localization for block or stimulation. J Urol 1989;142:1528–1531.

    PubMed  CAS  Google Scholar 

  56. Klink EW. Perineal nerve block. Obstet Gynecol 1953;1:137–146.

    PubMed  CAS  Google Scholar 

  57. Thoumas D, Leroi AM, Mauillon J, et al. Pudendal neuralgia: CT-guided pudendal nerve block technique. Abdom Imaging 1999;24:309–312.

    Article  PubMed  CAS  Google Scholar 

  58. McDonald, J. and D. Spigos, computed tomography – guided pudendal block for treatment of pelvic pain due to pudendal neuropathy. Obstet Gynecol 2000;2:306–309.

    Article  Google Scholar 

  59. Benson JT, Griffis K. Pudendal neuralgia, a severe pain syndrome. Am J Obstet Gynecol 2005;192(5):1663–1668.

    Article  PubMed  Google Scholar 

  60. Pecina MM, Krmpotic-Nemanic J, Markiewitz AD. Pudendal nerve syndrome (syndrome of Alcock’s tunnel). In: Tunnel Syndromes: Peripheral Nerve Compression Syndromes, 3rd ed. Boca Raton, FL: CRC Press. 2001:191–194.

    Google Scholar 

  61. Ellis W. Heparin alleviates pain in nerve entrapments. Am J Pain Med 2003;13:54–59.

    Google Scholar 

  62. Hough DM, Wittenberg KH, et al. Chronic perineal pain due to pudendal nerve entrapment: anatomy, pathophysiology, and techniques for CT-guided perineural injection. AJR 2003;186:561–567.

    Google Scholar 

  63. Thind P, Lose G. The effect of bilateral pudendal blockade on the static urethral closure function in healthy females. Obstet Gynecol 1992;80:906–911.

    PubMed  CAS  Google Scholar 

  64. Shafik A. Endoscopic pudendal canal decompression for the treatment of faecal incontinence due to pudendal canal syndrome. J Laparoendoscopic Advan Surg Tech 1997;7:227–234.

    CAS  Google Scholar 

  65. Mauillon J, Thoumas D, Leroi AM, et al. Results of pudendal nerve neurolysis-transposition in twelve patients suffering from pudendal neuralgia. Dis Colon Rectum 1999;42:186–192.

    Article  PubMed  CAS  Google Scholar 

  66. Beco J, Climov D, Bex M. Pudendal nerve decompression in perineology; a case series. BMC Surg 2004;4:15.

    Article  PubMed  Google Scholar 

  67. Robert R, Labat JJ, et al. Decompression and transposition of the pudendal nerve in pudendal neuralgia: a controlled trial and long-term evaluation. Eur Urol 2005;47:403–408.

    Article  PubMed  Google Scholar 

  68. Ramsden CE, McDaniel MC, et al. Pudendal nerve entrapment as source of intractable perineal pain. Am J Phys Med Rehabil 2003;82:479–484.

    Article  PubMed  Google Scholar 

  69. Gajraj NM. Botulinum toxin a injection of the obturator internus muscle for chronic pelvic pain. J Pain 2000;6:333–337.

    Article  CAS  Google Scholar 

  70. Litwin MS, Mcnaughton-Collins M, et al. The National Institutes of Health chronic prostatitis symptom index: development and validation of a new outcomes measure. J Urol 1999;369–375.

    Google Scholar 

  71. Barry MJ, Fowler FJ Jr., O, Leary MP, et al. The American Urological Association symptom index for benign prostatic hyperplasia. J Urol 1992;148:1549.

    PubMed  CAS  Google Scholar 

  72. Rosen RC, Cappelleri JC, Smith MD, et al. Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res 1999;11:319–326.

    Article  PubMed  CAS  Google Scholar 

  73. Rosen RC, Brown C, et al. The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Mar Ther 2000;26:191–208.

    Article  CAS  Google Scholar 

  74. Howard FM (ed). Pelvic Pain: Diagnosis and Management. Philadelphia, PA: Lippincott, Williams and Wilkins, 2000.

    Google Scholar 

  75. Krieger JN, Egan KJ, et al. Chronic pelvic pains represent the most prominent urogenital symptoms of “chronic prostatitis”. Urology 1996;48:715–722.

    Article  PubMed  CAS  Google Scholar 

  76. Schaeffer AJ, Landis JR, Snauss JS, et al. Demographic and clinical characteristics of men with chronic prostatitis: The National Institutes of Health Chronic Prostatitis Cohort Study. J Urol 2002;168:593–598.

    Article  PubMed  Google Scholar 

  77. Segura JW, Opitz JL, Greene LF. Prostatosis, prostatitis or pelvic floor tension myalgia? J Urol 1979;122:168–169.

    PubMed  CAS  Google Scholar 

  78. Rau SC, Hartfield RA. Paroxysmal anal hyperkinesis: a characteristic feature of proctalgia fugax. Gut 1996;39:609–612.

    Article  Google Scholar 

  79. Baskin LS, Tanagho EA. Pelvic pain without pelvic organs. J Urol 1992;147:683–686.

    PubMed  CAS  Google Scholar 

  80. Perry CP. Peripheral Neuropathies Presenting as Chronic Pelvic Pain. Presented at the 27th Annual Meeting of the International Congress of Gynecologic Endoscopy, November 11, 1998, Atlanta, GA. “Management of Pelvic Pain”.

    Google Scholar 

  81. Yeates, WK. Pain in the scrotum. Br J Hosp Med 1985;33:101–104.

    PubMed  CAS  Google Scholar 

  82. Rab M, Ebmer J, Dellon AL. Anatomic variability of the ilioinguinal and genitofemoral nerve: implications for the treatment of groin pain. Plast Reconstruct Surg 2001;108:1618–1623.82.

    Article  CAS  Google Scholar 

  83. Ries E. Episacroiliac lipoma. Am J Obstet Gynecol 1937;34:492–498.

    Google Scholar 

  84. Copeman WSC, Ackerman WL. Edema or herniations of fat lobules as a cause of lumbar and gluteal “fibrositis”. Arch Int Med 1947;79:22–35.

    Google Scholar 

  85. Curtis P. In Search of the ‘Back Mouse.’ J Fam Pract 1993;36(6):657–659.

    PubMed  CAS  Google Scholar 

  86. Ries E. Episacroiliac lipoma. Am J Obstet Gynecol 1937;34:492–4982.

    Google Scholar 

  87. Applegate WV. Abdominal cutaneous nerve entrapment syndrome. Surgery 1972;71:118–124.

    PubMed  CAS  Google Scholar 

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Antolak, S.J. (2008). Pudendal Neuralgia. In: Potts, J.M. (eds) Genitourinary Pain And Inflammation. Current Clinical Urology. Humana Press. https://doi.org/10.1007/978-1-60327-126-4_3

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  • DOI: https://doi.org/10.1007/978-1-60327-126-4_3

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