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Mechanical Loading of Blood Cells in Turbulent Flow

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Computational Biomechanics for Medicine

Abstract

Blood cells are subjected to turbulent flow in some disease states and in cardiovascular devices. In general, the details of the microscale flow and stress on cells are unknown for these flows. This chapter is a discussion and review of efforts to identify simple parameters that can quantify the effects of turbulence on cells. It is shown that Reynolds stress and Kolmogorov scale alone are not adequate descriptors of the turbulent flow. The energy spectrum of turbulence must be considered also, so that cell loading at all length scales is properly represented. A deeper quantitative model will require understanding of two-phase flow effects.

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Author information

Authors and Affiliations

  1. Mechanical Engineering, College of Engineering and Informatics, National University of Ireland, Galway, Ireland

    Nathan J. Quinlan

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  1. Nathan J. Quinlan
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Correspondence to Nathan J. Quinlan .

Editor information

Editors and Affiliations

  1. Intelligent Systems for Medicine Laboratory, The University of Western Australia, Perth, West Australia, Australia

    Barry Doyle

  2. Intelligent Systems for Medicine Laboratory, The University of Western Australia, Perth, West Australia, Australia

    Karol Miller

  3. Intelligent Systems for Medicine Laboratory, The University of Western Australia, Perth, West Australia, Australia

    Adam Wittek

  4. Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand

    Poul M.F. Nielsen

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Quinlan, N.J. (2014). Mechanical Loading of Blood Cells in Turbulent Flow. In: Doyle, B., Miller, K., Wittek, A., Nielsen, P. (eds) Computational Biomechanics for Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0745-8_1

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  • DOI: https://doi.org/10.1007/978-1-4939-0745-8_1

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-0744-1

  • Online ISBN: 978-1-4939-0745-8

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