Abstract
Atopic dermatitis is a chronic pruritic skin disease seen most commonly in persons with a personal or family history of “atopy” (i.e., asthma, allergic rhinitis, atopic dermatitis). There is no characteristic clinical, histological, or laboratory indicator of the disease; hence diagnosis depends on history and presence of several clinical features (Table 1). It would be difficult to make a firm diagnosis without at least three of these first five features. It may be necessary, especially with infants, to observe the patient for an extended period before the typical course and cutaneous morphology become evident.
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Hanifin, J.M. (1981). Atopic Dermatitis. In: Safai, B., Good, R.A. (eds) Immunodermatology. Comprehensive Immunology, vol 7. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-7228-2_19
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