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Minimizing occupational exposure to pesticides: Cholinesterase determination and organophosphorus poisoning

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Residue Reviews

Part of the book series: Residue Reviews ((RECT,volume 75))

Abstract

In most instances Cholinesterase determination in people is carried out either: (1) as part of a surveillance procedure to prevent poisoning in people exposed to organophosphorus compounds or (2) as a diagnostic tool to exclude or confirm that symptoms or signs observed in people are caused by anticholinesterase compounds.

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References

  • Aldridge, W. N., and E. Reiner: Enzyme inhibitors as substrates, p. 328. Amsterdam-London: North-Holland (1972).

    Google Scholar 

  • Arnan, A.: Experience in the WHO field programme for evaluating the safety of new insecticides. Bull. World Health Org. 44, 273 (1971).

    PubMed  CAS  Google Scholar 

  • Augustinsson, K.-B.: The normal variation of human blood Cholinesterase activity. Acta Physiol. Scand. 35, 40 (1955).

    Article  PubMed  CAS  Google Scholar 

  • Augustinsson, K.-B.: Determination of activity of cholinesterases. In D. Glick (ed.): Methods of biochemical analysis, suppl. vol. Analysis of biogenic amines and their related enzymes, pp. 217–273. New York: Interscience (1971).

    Google Scholar 

  • Augustinsson, H. Eriksson, and Y. Faijersson: A new approach to determining Cholinesterase activities in samples of whole blood. Clin. Chim. Acta 89, 239 (1978).

    Article  PubMed  CAS  Google Scholar 

  • Augustinsson, and B. Holmstedt: Determination of Cholinesterase in blood samples dried on filter-paper and its practical application. Scand. J. Clin. Lab. Invest. 17, 573 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Edson, E. F.: Blood tests for users of OP insecticides. World Crops 10, 49 (1958).

    Google Scholar 

  • Ellman, G. L., K. D. Courtey, V. Andres, Jr., and R. M. Featherstone: A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem. Pharmacol. 7, 88 (1961).

    Article  PubMed  CAS  Google Scholar 

  • Groff, W. A., A. Kaminskis, and R. I. Ellin: Interconversion of Cholinesterase enzyme activity units by the manual ApH method and a recommended automated method. Clin. Toxicol. 9, 353 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Holmstedt, B.: Simple microcentrifuge for use in the field. Science 149, 977 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Holmstedt, B.: Distribution and determination of eholinesterases in mammals. Bull. World Health Org. 44, 99 (1971).

    PubMed  CAS  Google Scholar 

  • Holmstedt, and J. L. Oudart: Mesure de l’activité eholinestérasique plasmatique sur le terrain au moyen d’un papier test. Bull. Soc. Path. exot. 59, 411 (1966).

    PubMed  CAS  Google Scholar 

  • Long, K. R.: Cholinesterase activity as a biological indicator of exposure to pesti-sides. Int. Arch. Occup. Environ. Health 36, 75 1975 ).

    Article  PubMed  CAS  Google Scholar 

  • Michel, O. H.: An electrometric method for the determination of red blood cell and plasma Cholinesterase activity. J. Lab. Clin. Med. 34, 1564 (1949).

    CAS  Google Scholar 

  • Namba, T.: Cholinesterase inhibition by organophosphorus compounds and its clinical effects. Bull. World Health Org. 44, 289 (1971).

    PubMed  CAS  Google Scholar 

  • Oudart, J. L., and B. Holmstedt: Determination of plasma Cholinesterase activity by means of a test paper and its use in the field. Arch. Toxicol. 27, 1 (1970).

    Article  CAS  Google Scholar 

  • Permanent Commission and International Association on Occupational Health, Subcommittee on Pesticides: Epidemiological toxicology of pesticide exposure. Report of an international workshop. Arch. Environ. Health 25, 399 (1972).

    Google Scholar 

  • Permanent Commission and International Association on Occupational Health, Subcommittee on Pesticides: Field worker exposure during pesticide application. Report of an international workshop, K. Jager (ed.). ( In press.) Amsterdam: Elsivier (1980).

    Google Scholar 

  • Plesitna, R.: Nasa iskustva u primjeni Acholest-metode za odredivanje aktivnosti kolinesteraze plazme covjeka (Our experience in applying acholest method for the determination of human plasma Cholinesterase activity). Arh. hig. rada 17, 291 (1966).

    Google Scholar 

  • Popendorf, W. J., and J. T. Leffingwell: Natural variations in the decay and oxidation of parathion foliar residues. J. Agr. Food Chem. 26, 437 (1978).

    Article  CAS  Google Scholar 

  • Ramussen, W. A., J. A. Jensen, W. J. Stein, and W. J. Hayes, Jr.: Toxicological studies of DDVP for disinsection of aircraft. Aerospace Med. 34, 593 (1963).

    Google Scholar 

  • Reiner, E., A. Buntic, M. Trdak, and V. Simeon: Effect of temperature on the activity of human blood eholinesterases. Arch. Toxicol. 32, 347 (1974).

    Article  PubMed  CAS  Google Scholar 

  • Richterich, R.: Bestimmung der Serumcholinesterase mit Hilfe eines Indikatorpapiers. Schweiz, med. Wschr. 92, 263 (1962).

    CAS  Google Scholar 

  • Sailer, S., and H. Braunsteiner: Über eine neue, sehr einfache Methode zur Bestimmung der Serumcholinesterase Activitat und ihre Klinische Bedeutung. Klin. Wschr. 37, 986 (1959).

    Article  PubMed  CAS  Google Scholar 

  • Simeon, V.: Metode za odredivanje aktivnosti kolinesteraza (Methods of estimating Cholinesterase activity). Arch. hig. rada 18, 383 (1967).

    CAS  Google Scholar 

  • Stubbs, J. L., and J. T. Fales: A capillary sampling technique for the determination of Cholinesterase activity in red cells and plasma. Amer. J. Med. Technol. 26, 25 (1960).

    CAS  Google Scholar 

  • Skrinjaric-Spoljar, M., V. Simeon, and E. Reiner: Spontaneous reactivation of dimethylphosphorylated acetylcholinesterase and Cholinesterase. Biochem. Biophys. Acta 315, 363 (1973).

    CAS  Google Scholar 

  • Vandekar, M.: Observations on the toxicity of carbaryl, folithion and 3-isopropyl- phenyl N-methylcarbamate in a village-scale trial in southern Nigeria. Bull. World Health Org. 33, 107 (1965).

    PubMed  CAS  Google Scholar 

  • Vandekar, M.: Monitoring of Cholinesterase activity in people exposed to insecticides during WHO trials. Unpublished mimeographed WHO document WHO/VBC/75.603 (1975).

    Google Scholar 

  • Vandekar, M., R. Plestina, and K. Wilhelm: Toxicity of carbamates for mammals. Bull. World Health Org. 44, 241 (1971).

    PubMed  CAS  Google Scholar 

  • Vandekar M., and B. Svetlicic: Observations on the toxicity of three anticholinesterase insecticides in a village scale trial and comparison of methods used for determining Cholinesterase activity. Arh. hig. rada 17, 135 (1966).

    PubMed  CAS  Google Scholar 

  • Watson, W. A., and E. F. Edson: The Tintometer Limited field Cholinesterase kit: Improvement in technique. Mimeographed report No. TOX/115, Med. Dept, Chesterford Park Station, Saffron Waiden, Essex, England (1964).

    Google Scholar 

  • Wilhelm, K.: Determination of human plasma Cholinesterase activity by adapted Ellmans method. Arh. hig. rada 19, 199 (1968).

    PubMed  CAS  Google Scholar 

  • Wilhelm, K.: Letter to WHO “Spectrophotometric kit for ChE determination,” Jan. 8 (1980).

    Google Scholar 

  • Wilhelm, K., and E. Reiner: Effect of sample storage on human blood Cholinesterase activity after inhibition by carbamates. Bull. World Health Org. 48, 235 (1973).

    PubMed  CAS  Google Scholar 

  • Wilhelm, K., M. Vandekar, and E. Reiner: Comparison of methods for measuring Cholinesterase inhibition by carbamates. Bull. World Health Org. 48, 41 (1973).

    PubMed  CAS  Google Scholar 

  • Winteringham, F. P. W., and R. W. Disney: A simple method for estimating blood Cholinesterase. Lab. Pract. 13, 739 (1964).

    CAS  Google Scholar 

  • Witter, R. F.: Measurement of blood Cholinesterase. Arch. Environ. Health 6, 537 (1963).

    CAS  Google Scholar 

  • World Health Organization: Safe use of pesticides in public health: Sixteenth report of the WHO Expert Committee on Insecticides. World Health Org. Tech. Rep. Ser. No. 356 (1967).

    Google Scholar 

  • World Health Organization: Safe use of pesticides: Twentieth report of the WHO Expert Committee on Insecticides. World Health Org. Tech. Rep. Ser. No. 513 (1973).

    Google Scholar 

  • World Health Organization: Spectrophotometric kit for measuring Cholinesterase activity. Unpublished mimeographed WHO document WHO/VBC/78.692 (1978).

    Google Scholar 

  • World Health Organization: Safe use of pesticides: Third report of the WHO Expert Committee on Vector Biology and Control. World Health Org. Tech. Rep. Ser. No. 634 (1979).

    Google Scholar 

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Vandekar, M. (1980). Minimizing occupational exposure to pesticides: Cholinesterase determination and organophosphorus poisoning. In: Gunther, F.A., Gunther, J.D. (eds) Residue Reviews. Residue Reviews, vol 75. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-6104-9_6

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  • DOI: https://doi.org/10.1007/978-1-4612-6104-9_6

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-6106-3

  • Online ISBN: 978-1-4612-6104-9

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