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Cytokines in the Genesis and Treatment of Cancer

  • Book
  • © 2007

Overview

  • Explores the clearly demonstrated link between cytokines and cancer
  • Highlights potential treatment strategies that take advantage of utilizing cytokine and anti-cytokine therapies
  • Contributions from internationally distinguished investigators
  • Covers TNF, IL-2, IL-12, and Type I interferons, among others
  • Practically divided into four useful parts

Part of the book series: Cancer Drug Discovery and Development (CDD&D)

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Table of contents (24 chapters)

  1. Infectious Agents, Cytokines, and Cancer

  2. Cytokines and Carcinogenesis

  3. Cytokines and Tumor Stroma/Metastasis

Keywords

About this book

Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume’s first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress — both in animal models and humans — in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the Genesis and Treatment of Cancer brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field.

Reviews

From the reviews:

"...brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer.  Together,, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field." -Anticancer Research

"This is a collection of papers from a large number of authors on the role of cytokines in the genesis of neoplastic diseases including metastatic spreads and the potential role in therapy. … Chronic cytokine production can contribute to the generation and progression of cancer. Mechanisms involved in this process are described in the many chapters of this volume. The book is highly recommended to all of those involved in the study of neoplastic diseases." (Julian L. Ambrus, The Journal of Medicine, March, 2008)

“This new volume in Humana’s series will be necessary reading for researchers, oncologists, pharmacologists, radiotherapists.” (Tumori, Vol. 93, 2007)

Editors and Affiliations

  • The Ohio State University Comprehensive Cancer Center, Columbus

    Michael A. Caligiuri

  • University of Pittsburgh Cancer Center, Pittsburgh

    Michael T. Lotze

Bibliographic Information

  • Book Title: Cytokines in the Genesis and Treatment of Cancer

  • Editors: Michael A. Caligiuri, Michael T. Lotze

  • Series Title: Cancer Drug Discovery and Development

  • DOI: https://doi.org/10.1007/978-1-59745-455-1

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2007

  • Hardcover ISBN: 978-0-89603-820-2Published: 20 April 2007

  • Softcover ISBN: 978-1-61737-203-2Published: 19 November 2010

  • eBook ISBN: 978-1-59745-455-1Published: 19 September 2007

  • Series ISSN: 2196-9906

  • Series E-ISSN: 2196-9914

  • Edition Number: 1

  • Number of Pages: XIX, 482

  • Topics: Cancer Research, Oncology, Pharmacology/Toxicology, Radiotherapy

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