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Silver nanoparticles: synthesis through chemical methods in solution and biomedical applications

  • Review Article
  • Published:
Central European Journal of Chemistry

Abstract

Chemical methods provide an easy way to synthesize silver nanoparticles (Ag NPs) in solution. These metal nanoparticles have a great potential for biomedical applications as an antibacterial, antifungal, and antiviral agent or in wound healing. The adjustment of the parameters involved in these reactions permits a precise control over the size, shape, monodispersity, and the surfaces of the nanoparticles. These nanoparticles are being used in the design of new hybrid organic-inorganic or inorganic nanomaterials for biomedical applications.

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References

  1. C.N.R. Rao, A. Müller, A.K. Cheetham (Eds), The Chemistry of Nanomaterials. Synthesis, Properties and Applications (Wiley-VCH Verlag, Weinheim, 2004) Vols. 1 and 2

    Google Scholar 

  2. C.N.R. Rao, A. Müller, A.K. Cheetham (Eds), Nanomaterials Chemistry. Recent Developments and New Directions (Wiley-VCH Verlag, Weinheim, 2007)

    Google Scholar 

  3. C. Burda, X. Chen, R. Narayanan, M.A. El-Sayed, Chem. Rev. 105, 1025 (2005)

    Article  CAS  Google Scholar 

  4. B.L. Cushing, V.L. Koleschineko, C.J. O’Connor, Chem. Rev. 104, 3893 (2004)

    Article  CAS  Google Scholar 

  5. H.J. Klasen, Burns 26, 117 (2000)

    Article  CAS  Google Scholar 

  6. H.J. Klasen, Burns 26, 131 (2000)

    Article  CAS  Google Scholar 

  7. D.J. Barber, I.C. Freestone, Archaeometry 32, 33 (1990)

    Article  Google Scholar 

  8. J. Pérez-Arantegui, A. Larrea, Trends Anal. Chem. 22, 327 (2003)

    Article  CAS  Google Scholar 

  9. A. Caiger-Smith, Lustre Pottery: Technique, Tradition and Innovation in Islam and the Western World (Faber & Faber, London, 1985)

    Google Scholar 

  10. L.M. Liz-Marzán, Materials Today Feb, 26, (2004)

  11. L.S. Nair, C. T. Laurencin, J. Biomed. Nanotechnol. 3, 301 (2007)

    Article  CAS  Google Scholar 

  12. D.D. Evanoff, Jr., G. Chumanov, ChemPhysChem. 6, 1221 (2005)

    Article  CAS  Google Scholar 

  13. P.C. Lee, D.J. Meisel, Phys. Chem. 86, 3391 (1982)

    Article  CAS  Google Scholar 

  14. J.A. Creighton, C.G. Blatchford, M.G. Albrecht, J. Chem. Soc. Farad. Trans. II 75, 790 (1979)

    Article  CAS  Google Scholar 

  15. K.P. Velikov, G.E. Zegers, A. van Blaaderen, Langmuir 19, 1384 (2003)

    Article  CAS  Google Scholar 

  16. L.K. Kurihara, G.M. Chow, P.E. Schoen, Nanostruct. Mater. 5, 607 (1995)

    Article  CAS  Google Scholar 

  17. J.A. Jacob, S. Kapoor, N. Biswas, T. Mukherjee, Colloids Surf., A Physicochem. Eng. Aspects 301, 329 (2007)

    Article  CAS  Google Scholar 

  18. P. Raveendran, J. Fu, S.L. Wallen, J. Am. Chem. Soc. 125, 13940, (2003)

    Article  CAS  Google Scholar 

  19. Y.D. Yin, Z.Y. Li, Z.Y. Zhong, B. Gates, Y.N. Xia, J. Mater. Chem. 12, 522 (2002)

    Article  CAS  Google Scholar 

  20. I. Pastoriza-Santos, L.M. Liz-Marzán, Pure Appl. Chem. 72, 83, (2000)

    Article  CAS  Google Scholar 

  21. I. Pastoriza-Santos, L.M. Liz-Marzán, Langmuir 18, 2888 (2002)

    Article  CAS  Google Scholar 

  22. I. Pastoriza-Santos, L.M. Liz-Marzán, Nano Lett. 2, 903 (2002)

    Article  CAS  Google Scholar 

  23. I. Pastoriza-Santos, D.S. Koktysh, A. A. Mamedov, M. Giersig, N. A. Kotov, L. M. Liz-Marzán, Langmuir 16, 2731 (2000)

    Article  CAS  Google Scholar 

  24. I. Pastoriza-Santos, L.M. Liz-Marzán, J. Mat. Chem. 18, 1724 (2008)

    Article  CAS  Google Scholar 

  25. M. Brust, C.J. Kiely, Colloids Surf. A Phys. Eng. Aspects 202, 175 (2002).

    Article  CAS  Google Scholar 

  26. M.M. Oliveira, D. Ugarte, D. Zanchet, A.J.G. Zarbin, J. Colloid Interface Sci. 292, 429 (2005)

    Article  CAS  Google Scholar 

  27. C.A. Bauer, F. Stellacci, J. W. Perry, Top. Catal. 47, 32 (2008)

    Article  CAS  Google Scholar 

  28. M. Yamamoto, M. Nakamoto, J. Mat. Chem. 13, 2064 (2003)

    Article  CAS  Google Scholar 

  29. Y. Kashiwagi, M. Yamamoto, M. Nakamoto, J. Colloid Interface Sci. 300, 169 (2006)

    Article  CAS  Google Scholar 

  30. M. Green, N. Allsop, G. Wakefield, P.J. Dobson, J.L. Hutchison, J. Mat. Chem. 12, 2671 (2002)

    Article  CAS  Google Scholar 

  31. H. Hiramatsu, F.E. Osterloh, Chem. Mater. 16, 2509 (2004)

    Article  CAS  Google Scholar 

  32. S. Nath, S. Praharaj, S. Panigrahi, S. Kundu, S.K. Ghosh, S. Basu, T. Pal, Colloids Surf. A Phys. Eng. Aspects 274, 145 (2006)

    Article  CAS  Google Scholar 

  33. S.D. Bunge, T.J. Boyle, T.J. Headley, Nano Lett. 3, 901, (2003)

    Article  CAS  Google Scholar 

  34. N.R. Jana, L. Gearheart, C.J. Murphy, Chem. Commun. 617 (2001)

  35. C.J. Murphy, N.R. Jana, Adv. Mat. 14, 80 (2002)

    Article  CAS  Google Scholar 

  36. S. Chen, D.L. Carroll Nano Lett 2, 1003 (2002)

    Article  CAS  Google Scholar 

  37. J.P. Cason, K. Khanbaswadkar, C.B. Roberts, Ind. Eng. Chem. Res. 39, 4749 (2000)

    Article  CAS  Google Scholar 

  38. M.P. Pileni, Pure Appl. Chem. 72, 53 (2000)

    Article  CAS  Google Scholar 

  39. M. Maillard, S. Giorgio, M.P. Pileni, J. Phys. Chem. B 107, 2466 (2003)

    Article  CAS  Google Scholar 

  40. W. Zhang, X. Qiao, J. Chen, H. Wang, J. Colloid Interface Sci. 302, 370 (2006)

    Article  CAS  Google Scholar 

  41. Y. Sun, Y. Xia, Science 298, 2176 (2002)

    Article  CAS  Google Scholar 

  42. H.H. Huang, X.P. Ni, G.L. Loy, C.H. Chew, K.L. Tan, F.C. Loh, J.F. Deng, G.Q. Xu, Langmuir 12, 909 (1996)

    Article  CAS  Google Scholar 

  43. Y. Tan, X. Dai, Y. Li, D. Zhu, J. Mater. Chem. 13, 1069 (2003)

    Article  CAS  Google Scholar 

  44. R. He, X. Qian, J. Yin, Z. Zhu, J. Mater. Chem. 12, 3783 (2002)

    Article  CAS  Google Scholar 

  45. Y. Sun, Y. Xia, Adv. Mat. 14, 833 (2002)

    Article  CAS  Google Scholar 

  46. B. Wiley, Y. Sun, B. Mayers, Y. Xia, Chem. Eur. J. 11, 454 (2005)

    Article  CAS  Google Scholar 

  47. Z.Q. Zhang, R.C. Patel, R. Kothari, C.P. Johnson, S.E. Friberg, P.A. Aikens, J. Phys. Chem. B 104, 1176 (2000)

    Article  CAS  Google Scholar 

  48. Q. Yang, F. Wang, K.B. Tang, C.R. Wang, Z.W. Chen, Y.T. Qian, Mater. Chem. Phys. 78, 495 (2002)

    Article  Google Scholar 

  49. Z.P. Zhang, M.Y. Han, J. Mater. Chem. 13, 641 (2003)

    Article  CAS  Google Scholar 

  50. M. Cheng, L. Wang, J. Han, J. Zhang, Z. Lin, D. Qian, J. Chem. Phys. B 110, 11224 (2006)

    Article  CAS  Google Scholar 

  51. K. Mallick, M.J. Witcomb, M.S. Scurrell, Mater. Sci. Eng., C 26, 87 (2006)

    Article  CAS  Google Scholar 

  52. X. Sun, S. Dong, E. Wang, Macromolecules 37, 7105 (2004)

    Article  CAS  Google Scholar 

  53. W. Lesniak, A.U. Bielinska, K. Sun, K.W. Janczak, X. Shi, J.R. Baker, Jr., L.P. Balogh, Nano Lett. 5, 2123 (2005)

    Article  CAS  Google Scholar 

  54. J. Zheng, R.M. Dickson, J. Am. Chem. Soc. 123, 13982 (2002)

    Article  CAS  Google Scholar 

  55. H. Huang, X. Yang, Carbohydr Res 339, 2627 (2004)

    Article  CAS  Google Scholar 

  56. Q. Wu, H. Cao, Q. Luan, J. Zhang, Z. Wang, J.H. Warner, A.A.R. Watt, Inorg. Chem. 47, 5882 (2008)

    Article  CAS  Google Scholar 

  57. A. Mantion, A.G. Guex, A. Foelske, L. Mirolo, K.M. Fromm, M. Painsid, A. Taubert, Soft Matter. 4, 606 (2008)

    Article  CAS  Google Scholar 

  58. D. Yu, V.W.-W. Yam, J. Am. Chem. Soc. 126, 13200 (2004)

    Article  CAS  Google Scholar 

  59. D. Yu, V.W.-W. Yam, J. Chem. Phys. B 109, 5497 (2005)

    Article  CAS  Google Scholar 

  60. R. Jin, Y. Cao, C.A. Mirkin, K.C. Kelly, G.C. Schatz, J.G. Zheng, Science 294, 1901 (2001)

    Article  CAS  Google Scholar 

  61. R. Jin, Y.C. Cao, E. Hao, G.S. Metraux, G.C. Schartz, C.A. Mirkin, Nature 425, 487 (2003)

    Article  CAS  Google Scholar 

  62. A. Troupis, A. Hiskia, E. Papaconstantinou, Angew Chem. Int. Ed. 41, 1911 (2002)

    Article  CAS  Google Scholar 

  63. E.J. Fernández, J. García-Barrasa, A. Laguna, J.M. López-de-Luzuriaga, M. Monge, C. Torres, Nanotechnology 19, 185602 (6pp) (2008)

    Article  CAS  Google Scholar 

  64. K. Philippot, B. Chaudret, C. R. Chimie 6, 1019 (2003)

    Article  CAS  Google Scholar 

  65. B. Chaudret, C. R. Physique 6, 117 (2005)

    Article  CAS  Google Scholar 

  66. M. Monge, M. L. Kahn, A. Maisonnat, B. Chaudret, Angew. Chem., Int. Ed. 42, 5321 (2003)

    Article  CAS  Google Scholar 

  67. H. Schmidbaur, A. Grohmann, M.E. Olmos, A. Schier, In: S. Patai, Z. Rappoport (Eds), PATAI’s Chemistry of Functional Groups Organic Derivatives of Gold and Silver (John Wiley & Sons, Chichester 1999)

    Google Scholar 

  68. J.R. Morones, J.L. Elechiguerra, A. Camacho, K. Holt, J.B. Kouri, J.T. Ramírez, M.J. Yacaman, Nanotechnology 16, 2346 (2005)

    Article  CAS  Google Scholar 

  69. J.L. Elechiguerra, J.L. Burt, J.R. Morones, A. Camacho-Bragado, X. Gao, H.H. Lara, M.J. Yacaman, J. Nanobiotechnology 3, 6 (2005)

    Article  Google Scholar 

  70. C.N. Lok, C.M. Ho, R. Chen, Q.Y. He, W.Y. Yu, H. Sun, P.K.H. Tam, J.F. Chiu, C.M. Che, J. Proteome Res. 5, 916 (2006)

    Article  CAS  Google Scholar 

  71. C.N. Lok, C.M. Ho, R. Chen, Q.Y. He, W.Y. Yu, H. Sun, P.K.H. Tam, J.F. Chiu, C.M. Che, J. Biol. Inorg. Chem. 12, 527 (2007)

    Article  CAS  Google Scholar 

  72. N.V. Ayala-Núñez, H.H. Lara Villegas, L del C. Ixtepan Turrent, C. Rodríguez Padilla, Nanobiotechnol. 5, 1551 (2009)

    Article  CAS  Google Scholar 

  73. S. Pal, Y.K. Tak, J.M. Song, Appl. Environ. Microb. 73, 1712 (2007)

    Article  CAS  Google Scholar 

  74. N. Nino-Martinez, G.A. Martinez-Castanon, A. Aragon-Pina, F. Martinez-Gutierrez, J.R. Martinez-Mendoza, F. Ruiz, Nanotechnology 19, 065711 (2008)

    Article  CAS  Google Scholar 

  75. D. Guin, S.V. Manorama, J.N.L. Latha, S. Singh, J. Phys. Chem. C 111, 13393 (2007)

    Article  CAS  Google Scholar 

  76. B.S. Necula, L.E. Fratila-Apachitei, S.A.J. Zaat, I. Apachitei, J. Duszczyk, Acta Biomater. 5, 3573 (2009)

    Article  CAS  Google Scholar 

  77. J. Mungkalasiri, L. Bedel, F. Emieux, J. Doré, F.N.R. Renaud, C. Sarantopoulos, F. Maury Chem. Vapor Depos. 16, 35 (2010)

    Article  CAS  Google Scholar 

  78. S.K. Arumugam, TP. Sastry, SB. Sreedhar, A.S. Mandal, J. Biomed. Mater. Res. 80A, 391 (2007)

    Article  CAS  Google Scholar 

  79. F.A. Sheikh, N.A.M. Barakat, M.A. Kanjwal, R. Nirmala, J.H. Lee, H. Kim, H.Y. Kim, J. Mater. Sci.: Mater. Med. 21, 2551 (2010)

    Article  CAS  Google Scholar 

  80. M. Miranda, A. Fernández, M. Díaz, L. Esteban-Tejeda, S. López-Esteban, F. Malpartida, R. Torrecillas, J.S. Moya, Int. J. Mater. Res. 122 (2010)

  81. J. Shen, M. Shi, N. Li, B. Yan, H. Ma, Y. Hu, M. Ye, Nano Res. 3, 339 (2010)

    Article  CAS  Google Scholar 

  82. V.K. Rangari, G.M. Mohammad, S. Jeelani, A. Hundley, K. Vig, S.R. Singh, S. Pillai, Nanotechnology 21, 095102 (2010)

    Article  CAS  Google Scholar 

  83. O. Akhavan, E. Ghaderi, Curr. Appl. Physics 9, 1381 (2009)

    Article  Google Scholar 

  84. L. Jiang, W. Wang, D. Wu, J. Zhan, Q. Wang, Z. Wu, R. Jin, Mater. Chem. Phys. 104, 230 (2007)

    Article  CAS  Google Scholar 

  85. W. Lu, G. Liu, S. Gao, S. Xing, J. Wang, Nanotechnology 19, 445711 (2008)

    Article  CAS  Google Scholar 

  86. H. Koga, T. Kitaoka, H. Wariishi, J. Mat. Chem. 19, 2135 (2009)

    Article  CAS  Google Scholar 

  87. P. Gong, H. Li, X. He, K. Wang, J. Hu, W. Tan, S. Zhang, X. Yang, Nanotechnology 18, 285604 (2007)

    Article  CAS  Google Scholar 

  88. B. Chudasama, A.K. Vala, N. Andhariya, R.V. Upadhyay, R.V. Mehta, Nano Res. 2, 955 (2009)

    Article  CAS  Google Scholar 

  89. H. Miyoshi, H. Ohno, K. Sakai, N. Okamura, H. Kourai, J. Coll. Interface Sci. 345, 433 (2010)

    Article  CAS  Google Scholar 

  90. O. Ozay, A. Akcali, M.T. Otkun, C. Silan, N. Aktas, N. Sahiner, Colloids Surf. B 79, 460 (2010)

    Article  CAS  Google Scholar 

  91. Y.M. Mohan, K. Vimala, V. Thomas, K. Varaprasad, B. Sreedhar, S.K. Bajpai, K.M. Raju, J. Coll. Interface Sci. 342, 73 (2010)

    Article  CAS  Google Scholar 

  92. P. Jain, T. Pradeep, Biotechnol. Bioeng. 90, 59, (2005)

    Article  CAS  Google Scholar 

  93. R. Bryaskova, D. Pencheva, M. Kyulavska, D. Bozukova, A. Debuigne, C. Detrembleur, J. Coll. Interface Sci. 344, 424 (2010)

    Article  CAS  Google Scholar 

  94. K. Vimala, Y.M. Mohan, K.S. Sivudu, K. Varaprasad, S. Ravindra, N.N. Reddy, Y. Padma, B. Sreedhar, K.M. Raju, Colloids Surf. B 76, 248 (2010)

    Article  CAS  Google Scholar 

  95. L. Balogh, D. Swanson, D. Tomalia, G. Hagnauer, A. McManus, Nano Lett. 1, 18 (2001)

    Article  CAS  Google Scholar 

  96. Y. Zhang, H. Peng, W. Huang, Y. Zhou, D. Yan, J. Coll. Interface Sci. 325, 371 (2008)

    Article  CAS  Google Scholar 

  97. S. Jaiswal, B. Duffy, A.K. Jaiswal, N. Stobie, P. McHale, Int. J. Antimicrob. Agents 36, 280 (2010)

    Article  CAS  Google Scholar 

  98. M. Veerapandian, S.K. Lim, H.M. Nam, G. Kuppannan, K.S. Yun, Anal. Bioanal. Chem. 398, 867 (2010)

    Article  CAS  Google Scholar 

  99. R.W.-Y. Sun, R. Chen, N.P.-Y. Chung, C.-M. Ho, C.-L.-S. Lin, C.-M. Che, Chem. Commun. 5059 (2005)

  100. J.S. Kim, E. Ku, K.N. Yu, J. Kim, S.J. Park, H.J. Lee, S.H. Kim, Y.K. Park, Y.H. Park, C. Hwang, Y. Kim, Y. Lee, D.H. Jeong, M. Cho, Nanomedicine: Nanotechnology, Biology and Medicine 3, 95 (2007)

    Article  CAS  Google Scholar 

  101. J. Tian, K.K.Y. Wong, C.M. Ho, C.N. Lok, W.Y. Yu, C.M. Che, J.F. Chiu, P.K.H. Tam, ChemMedChem. 2, 129, (2007)

    Article  CAS  Google Scholar 

  102. D. Cheng, J. Yang, Y. Zhao, Chin. Med. Equip. J. 4, 26 (2004)

    Google Scholar 

  103. P. Muangman, C. Chuntrasakul, S. Silthram, S. Suvanchote, R. Benjathanung, S. Kittidacha, S. Rueksomtawin, J. Med. Assoc. Thai. 89, 953 (2006)

    Google Scholar 

  104. M.S. Cohen, J.M. Stern, A.J. Vanni, R.S. Kelley, E. Baumgart, D. Field, J.A. Libertino, I.C. Summerhayes, Surg. Infect. 8, 397 (2007)

    Article  Google Scholar 

  105. A.B. Lansdown, Curr. Probl. Dermatol. 33, 17 (2006)

    Article  CAS  Google Scholar 

  106. Z. Zhang, M. Yang, M. Huang, Y. Hu, J. Xie, Chin. J. Health Lab.Technol. 17, 1403 (2007)

    CAS  Google Scholar 

  107. D. Roe, B. Karandikar, N. Bonn-Savage, B. Gibbins, J.P. Roullet, J. Antimicrob. Chemother. 61, 869 (2008)

    Article  CAS  Google Scholar 

  108. W. Chen, Y. Liu, H.S. Courtney, M. Bettenga, C.M. Agrawal, J.D. Bumdgardner, J.L. Ong, Biomaterials 27, 5512 (2006)

    Article  CAS  Google Scholar 

  109. N.G. Khlebtsov, L.A. Dykman, J. Quant Spectr. Radiat. Transfer 1, 111 (2010)

    Google Scholar 

  110. M. Rai, A. Yadav, A. Gade, Biotecnol. Adv. 27, 76 (2009)

    Article  CAS  Google Scholar 

  111. R. Vaidyanathan, K. Kalishwaralal, S. Gopalram, S. Gurunathan, Biotecnol. Adv. 27, 924 (2010)

    Article  CAS  Google Scholar 

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  1. Chemistry Department, University of La Rioja, Grupo de Síntesis Química de La Rioja UA-CSIC, 26004, Logroño, Spain

    Jorge García-Barrasa, José M. López-de-Luzuriaga & Miguel Monge

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  1. Jorge García-Barrasa
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  2. José M. López-de-Luzuriaga
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  3. Miguel Monge
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Correspondence to Miguel Monge.

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García-Barrasa, J., López-de-Luzuriaga, J.M. & Monge, M. Silver nanoparticles: synthesis through chemical methods in solution and biomedical applications. cent.eur.j.chem. 9, 7–19 (2011). https://doi.org/10.2478/s11532-010-0124-x

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