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Identification and determination of mycotoxins and food additives in feed by HPLC–high-resolution time-of-flight mass spectrometry

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Abstract

High-resolution time-of-flight mass spectrometry combined with high performance liquid chromatography is proposed for the detection and determination of 25 mycotoxins and 8 food additives (coccidiostats) in animal feed, using simplified and rapid sample preparation. We developed a procedure for the identification and determination of analytes by the standard addition method. The lower limit of the analytical range is 1 (400) µg/kg for mycotoxins; the analytical range for coccidiostats in feed is 10–200 mg/kg. The relative standard deviation of the results does not exceed 10%. The analysis time is 0.5–1 h.

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Authors and Affiliations

  1. Federal Centre for Animal Health, Vladimir, 600901, Russia

    V. G. Amelin & A. A. Timofeev

  2. Vladimir State University, ul. Gor’kogo 87, Vladimir, 600000, Russia

    V. G. Amelin & A. A. Timofeev

Authors
  1. V. G. Amelin
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  2. A. A. Timofeev
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Correspondence to V. G. Amelin.

Additional information

Original Russian Text © V.G. Amelin, A.A. Timofeev, 2016, published in Zhurnal Analiticheskoi Khimii, 2016, Vol. 71, No. 4, pp. 428–435.

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Amelin, V.G., Timofeev, A.A. Identification and determination of mycotoxins and food additives in feed by HPLC–high-resolution time-of-flight mass spectrometry. J Anal Chem 71, 410–417 (2016). https://doi.org/10.1134/S106193481604002X

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  • DOI: https://doi.org/10.1134/S106193481604002X

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