Abstract
A method is proposed for the simultaneous identification and determination of 19 β-agonists by exact ion masses in feed, meat, liver, and kidneys of animals using high-resolution time-of-flight mass spectrometry combined with HPLC and simple and fast sample preparation. Matrix effects under the conditions of electrospray ionization were eliminated by the dilution of the extract with a 10-fold volume of deionized water. A scheme of the identification and determination of analytes by the standard addition method is proposed. The limits of detection are 0.11–10 ng/g and limits of quantification, 0.34–31 ng/g. The relative standard deviation of the results of analysis does not exceed 13%. The time of analysis is 1–2 h.
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Original Russian Text © V.G. Amelin, A.I. Korotkov, A.M. Andoralov, 2016, published in Zhurnal Analiticheskoi Khimii, 2016, Vol. 71, No. 6, pp. 626–633.
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Amelin, V.G., Korotkov, A.I. & Andoralov, A.M. HPLC—high-resolution time-of-flight mass spectrometry: Identification and determinarion of β-agonists in food and feed. J Anal Chem 71, 598–604 (2016). https://doi.org/10.1134/S1061934816060034
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DOI: https://doi.org/10.1134/S1061934816060034