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Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites

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A Correction to this article was published on 01 May 1997

Abstract

Dual intracellular recordings from microscopically identified neurons in the hippocampus reveal that the synaptic terminals of three morphologically distinct types of interneuron act through GABAA receptors. Each type of interneuron forms up to 12 synaptic contacts with a postsynaptic principal neuron, but each interneuron innervates a different domain of the surface of the postsynaptic neuron. Different kinetics of the postsynaptic effects, together with the strategic placement of synapses, indicate that these GABAergic interneurons serve distinct functions in the cortical network.

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Authors and Affiliations

  1. Medical Research Council, Anatomical Neuropharmacology Unit, Oxford University, Mansfield Road, Oxford, 0X1 3TH, UK

    Eberhard H. Buhl, Katalin Halasy & Peter Somogyi

  2. Department of Zoology, Jozsef Attila University, Szeged, Hungary

    Katalin Halasy

Authors
  1. Eberhard H. Buhl
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  2. Katalin Halasy
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  3. Peter Somogyi
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Buhl, E., Halasy, K. & Somogyi, P. Diverse sources of hippocampal unitary inhibitory postsynaptic potentials and the number of synaptic release sites. Nature 368, 823–828 (1994). https://doi.org/10.1038/368823a0

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