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Acetylcholine as an excitatory neuromuscular transmitter in the stomatogastric system of the lobster

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A Corrigendum to this article was published on 24 January 1975

Abstract

THERE is much physiological evidence that L-glutamate acts as an excitatory transmitter at many arthropod neuromuscular synapses1–3. The only suggestion that acetylcholine (ACh) has such a function is due to Futamachi4. He showed that the nerve terminal region innervated by the largest crayfish slow flexor excitatory motor neurone is depolarised by iontophoretic applications of ACh, but not L-glutamate. I now have biochemical and physiological evidence that ACh is the neurotransmitter at some, but not all, of the excitatory neuromuscular synapses of the lobster stomatogastric system.

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References

  1. Takeuchi, A., and Takeuchi, N., J. Physiol., 170, 296–317 (1964).

    Article  CAS  Google Scholar 

  2. Beránek, R., and Miller, P. I., J. exp. Biol., 49, 83–93 (1968).

    Google Scholar 

  3. Usherwood, P. N. R., and Machili, P., J. exp. Biol., 49, 341–361 (1968).

    CAS  Google Scholar 

  4. Futamachi, K. J., Science, 175, 1373–1375 (1972).

    Article  ADS  CAS  Google Scholar 

  5. Maynard, D. M., and Dando, M. R., Phil. Trans. R. Soc. London, ser. B, 268, 161–220 (1970).

    Article  ADS  Google Scholar 

  6. Maynard, D. M., Ann. N.Y. Acad. Sci., 193, 59–72 (1972).

    Article  ADS  CAS  Google Scholar 

  7. Mulloney, B., and Selverston, A. I., J. comp. Physiol., 91, 1–32 (1974).

    Article  Google Scholar 

  8. McCaman, R. E., Weinreich, D., and Boyrs, H., J. Neurochem., 21, 473–476 (1973).

    Article  CAS  Google Scholar 

  9. Giller, E., jun., and Schwartz, J. H., J. Neurophysiol., 34, 93–107 (1971).

    Article  CAS  Google Scholar 

  10. Coggeshall, R. E., Dewhurst, S. A., Weinreich, D., and McCaman, R. E., J. Neurobiol., 3, 259–265 (1972).

    Article  CAS  Google Scholar 

  11. Marder, E., thesis, Univ. California, San Diego (1974).

  12. Maynard, D. M., and Atwood, H. A., Am. Zool., 9, 1007 (1969).

    Google Scholar 

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MARDER, E. Acetylcholine as an excitatory neuromuscular transmitter in the stomatogastric system of the lobster. Nature 251, 730–731 (1974). https://doi.org/10.1038/251730a0

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  • DOI: https://doi.org/10.1038/251730a0

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