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Lack of Porosity of the Mouse Placenta to Maternal Cells

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Abstract

RECENT papers by Tuffrey, Bishun and Barnes1,2 have evoked great interest, because they have challenged the hitherto conventional views on the integrity of the placental barrier to maternal cells. They first reported finding an often substantial proportion (up to 33 per cent) of cells of maternal origin in certain tissues of mice aged between 4 and 60 days, which had developed in the uterus of a foster mother after transplantation at the blastocyst stage. Subsequently, they found maternal type cells in offspring from, normal pregnancies.

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References

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Authors and Affiliations

  1. Paediatric Research Unit, Guy's Hospital Medical School, London, SE1

    MARY J. SELLER

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  1. MARY J. SELLER
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SELLER, M. Lack of Porosity of the Mouse Placenta to Maternal Cells. Nature 225, 1254–1255 (1970). https://doi.org/10.1038/2251254a0

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  • DOI: https://doi.org/10.1038/2251254a0

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