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Mobilization of Lymphocytes from Lymph Nodes and Spleen by Polysaccharide Polysulphate

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Abstract

ONE of us has reported the production of lymphocytosis by polysaccharide polysulphates in experimental animals1. Maximal lymphocytosis was observed 3 h after administration of sulphated polysaccharides, and so lymphocytosis seems to be caused by the mobilization of lymphocytes from storage. The investigation described here was carried out to find the place or places from which the lymphocytes are mobilized into the circulating blood.

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References

  1. Sasaki, S., Nature, 214, 1041 (1967).

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  2. Yoffey, J. M., and Courtice, F. C., Lymphatics, Lymph and Lymphoid Tissue, 28 (Harvard University Press, 1956).

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SASAKI, S., SUCHI, T. Mobilization of Lymphocytes from Lymph Nodes and Spleen by Polysaccharide Polysulphate. Nature 216, 1013–1014 (1967). https://doi.org/10.1038/2161013a0

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  • DOI: https://doi.org/10.1038/2161013a0

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