Derivatives of lappaconitine containing styryl, hetarylvinyl, 3-oxobutenyl, and acetyl substituents on the aromatic ring were synthesized using a Heck reaction of 5′-iodolappaconitine and various olefines.
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The work was supported financially by the Russian Foundation for Basic Research (Project No. 11-03-00242).
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Translated from Khimiya Prirodnykh Soedinenii, No. 1, January–February, 2013, pp. 58–61.
For No. XVIII, see [1].
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Romanov, V.E., Shul’ts, E.E., Shakirov, M.M. et al. Alkaloids of the Flora of Siberia and Altai. XIX. Synthesis of new lappaconitine derivatives on the aromatic ring. Chem Nat Compd 49, 66–69 (2013). https://doi.org/10.1007/s10600-013-0506-3
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DOI: https://doi.org/10.1007/s10600-013-0506-3