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Vaginal mesh erosion after transvaginal repair of cystocele using Gynemesh or Gynemesh-Soft in 138 women: a comparative study

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Abstract

The objective of this study was to compare mesh erosion after transvaginal repair of cystocele using Gynemesh or Gynemesh-Soft mesh. We retrospectively analyzed 138 consecutive cases of transvaginal repair of cystocele using synthetic mesh. The study endpoint was the pathological evidence of vaginal erosion. Multiple logistic regression was used to determine independent predictors of vaginal erosion. One hundred and thirty eight women (ages 30–83 years) with cystocele between October 1999 and October 2004, from a French University Hospital, participated in this study. Cystocele repair was performed in all patients according to the technique of tension-free polypropylene mesh. The median follow-up was 32.1 months (range 7.5–59.9) in the Gynemesh group and 7.1 months (range 1–21.9) in the Gynemesh-Soft group. Vaginal erosion was reported in 27 (20%) of the patients. Anatomically, the success rate was 95% (131/138). There was no statistically significant difference between the Gynemesh and the Gynemesh-Soft meshes [the rate of vaginal erosion of the mesh was 16% (15/89) vs 24% (12/49), respectively, p=0.39]. Univariate analysis only identified age class as factor significantly associated with the probability of vaginal erosion. Multivariate analysis revealed that age class is an independent predictive factor of vaginal erosion (age > 70 years, odds ratio (OR) 3.6, 95% confidence interval (CI) 1.3–9.7, p=0.010). Furthermore cystocele stage > 2 (Baden and Walker classification) is a protective factor against vaginal erosion (OR 0.3, 95% CI 0.1–0.8, p=0.016). Thirteen symptomatic patients (13/27, 48%) necessitated a partial excision of the mesh, associated with a vaginal mucosal closure. Two patients (2/27, 7%) underwent a complete excision of the mesh. The incidence of de novo dyspareunia was 9% in patients with vaginal erosion and 11% in patient without mesh erosion (p=0.85). There was no occurrence of bladder or urethral erosion and no vaginal or pelvic infection. Isolated vaginal erosion of the mesh did not prove to be problematic. Gynemesh-Soft mesh does not decrease the incidence of vaginal erosion. Age > 70 years is an independent predictive factor of vaginal erosion. We recommend that mesh placement by vaginal route should be avoided by women with moderate cystocele. Where possible, total hysterectomy and vertical incision should also be avoided. Management of vaginal erosion is simple and is associated with a low rate of morbidity. However, patients should be informed that vaginal erosion of the mesh can occur. A multivariate analysis reveals that the incidence of vaginal erosion is not significantly different between Gynemesh and Gynemesh-Soft meshes. Other factors of erosion are analyzed.

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References

  1. Shull BL (1999) Pelvic organ prolapse: anterior, superior, and posterior vaginal segment defects. Am J Obstet Gynecol 181:6–11

    Article  PubMed  CAS  Google Scholar 

  2. Weber AM, Walters MD, Piedmonte MR, Ballard LA (2001) Anterior colporrhaphy: a randomised trial of three surgical techniques. Am J Obstet Gynecol 185:1299–1306

    Article  PubMed  CAS  Google Scholar 

  3. de Tayrac R, Gervaise A, Chauveaud-Lambling A, Fernandez H (2004) Combined genital prolapse repair reinforced with a polypropylene mesh and tension-free vaginal tape in women with genital prolapse and stress urinary incontinence: a retrospective case-control study with short-term follow-up. Acta Obstet Gynecol Scand 83:950–954

    Article  PubMed  Google Scholar 

  4. Yan A, Anne M, Karine A, Vanessa F, Christophe P, Anne T, Patrick M (2004) Cystocele repair by a synthetic vaginal mesh secured anteriorly through the obturator foramen. Eur J Obstet Gynecol Reprod Biol 115:90–94

    Article  PubMed  Google Scholar 

  5. Bader G, Fauconnier A, Roger N, Heitz D, Ville Y (2004) Cystocele repair by vaginal approach with a tension-free transversal polypropylene mesh. Technique and results. Gynecol Obstet Fertil 32:280–284

    Article  PubMed  CAS  Google Scholar 

  6. de Tayrac R, Gervaise A, Fernandez H (2002) Cystocele repair by the vaginal route with a tension-free polypropylene mesh. J Gynecol Obstet Biol Reprod 31:597–599

    Google Scholar 

  7. Baden WF, Walker TA (1972) Genesis of the vaginal profile: a correlated classification of vaginal relaxation. Clin Obstet Gynecol 15:1048–1054

    Article  PubMed  CAS  Google Scholar 

  8. Bump RC, Mattiasson A, Bo K, Brubaker LP, DeLancey JO, Klarskov P, Shull BL, Smith AR (1996) The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol 175:10–17

    Article  PubMed  CAS  Google Scholar 

  9. Milani R, Salvatore S, Soligo M, Pifarotti P, Meschia M, Cortese M (2005) Functional and anatomical outcome of anterior and posterior vaginal prolapse repair with prolene mesh. BJOG 112:107–111

    Article  PubMed  Google Scholar 

  10. Amid PK, Lichtenstein IL (1997) Current assessment of Lichtenstein tension-free hernia repair. Chirurg 68:959–964

    Article  PubMed  CAS  Google Scholar 

  11. Birch C, Fynes MM (2002) The role of synthetic and biological prostheses in reconstructive pelvic floor surgery. Curr Opin Obstet Gynecol 14:527–535

    Article  PubMed  Google Scholar 

  12. Dwyer PL, O’Reilly BA (2004) Transvaginal repair of anterior and posterior compartment prolapse with atrium polypropylene mesh. Br J Obstet Gynaecol 111:831–836

    Google Scholar 

  13. Adhoute F, Soyeur L, Pariente JL, Le Guillou M, Ferriere JM (2004) Use of transvaginal polypropylene mesh (Gynemesh) for the treatment of pelvic floor disorders in women. Prospective study in 52 patients. Prog Urol 14:192–196

    PubMed  Google Scholar 

  14. Debodinance P, Berrocal J, Clave H, Cosson M, Garbin O, Jacquetin B, Rosenthal C, Salet-Lizee D, Villet R (2004) Changing attitudes on the surgical treatment of urogenital prolapse: birth of the tension-free vaginal mesh. J Gynecol Obstet Biol Reprod 33:577–588

    CAS  Google Scholar 

  15. Achtari C, Hiscock R, O’reilly BA, Schierlitz L, Dwyer PL (2005) Risk factors for mesh erosion after transvaginal surgery using polypropylene (Atrium) or composite polypropylene/polyglactin 910 (Vypro II) mesh. Int Urogynecol J Pelvic Floor Dysfunct (2005 Jan 19, epub ahead of print) "DOI 10.1007/s00192-004-1272-3"

  16. Kobashi KC, Govier FE (2003) Management of vaginal erosion of polypropylene mesh slings. J Urol 169:2242–2243

    Article  PubMed  CAS  Google Scholar 

  17. Jamieson DJ, Steege JF (1996) The prevalence of dysmenorrhea, dyspareunia, pelvic pain, and irritable bowel syndrome in primary care practices. Obstet Gynecol 87:55–58

    Article  PubMed  CAS  Google Scholar 

  18. Versi E, Harvey MA, Cardozo L, Brincat M, Studd JW (2001) Urogenital prolapse and atrophy at menopause: a prevalence study. Int Urogynecol J Pelvic Floor Dysfunct 12:107–110

    Article  PubMed  CAS  Google Scholar 

  19. Mage P (1999) Interposition of a synthetic mesh by vaginal approach in the cure of genital prolapse. J Gynecol Obstet Biol Reprod 28:825–829

    CAS  Google Scholar 

  20. Julian TM (1996) The efficacy of Marlex mesh in the repair of severe, recurrent vaginal prolapse of the anterior midvaginal wall. Am J Obstet Gynecol 175:1472–1475

    Article  PubMed  CAS  Google Scholar 

  21. Nicita G (1998) A new operation for genitourinary prolapse. J Urol 160:741–745

    Article  PubMed  CAS  Google Scholar 

  22. Flood CG, Drutz HP, Waja L (1998) Anterior colporrhaphy reinforced with Marlex mesh for the treatment of cystoceles. Int Urogynecol J 9:200–204

    Article  CAS  Google Scholar 

  23. Migliari R, De Angelis M, Madeddu G, Verdacchi T (2000) Tension-free vaginal mesh repair for anterior vaginal wall prolapse. Eur Urol 38:151–155

    Article  PubMed  CAS  Google Scholar 

  24. Hardiman P, Oyawoye S, Browning J (2000) Cystocele repair using polypropylene mesh. Br J Obstet Gynecol 107:825–826

    Google Scholar 

  25. Sergent F, Marpeau L (2003) Prosthetic restoration of the pelvic diaphragm in genital urinary prolapse surgery trans-obturator and infracoccygeal hammock technique. J Gynecol Obstet Biol Reprod 32:120–126

    CAS  Google Scholar 

  26. Shah DK, Paul EM, Rastinehad AR, Eisenberg ER, Baldani GH (2004) Short-term outcome analysis of total pelvis reconstruction with mesh: the vaginal approach. J Urol 171:261–263

    Article  PubMed  Google Scholar 

  27. Cosson M (2004) Risk of infection and prostheses: time out or a red flag? J Gynecol Obstet Biol Reprod 33:559–560

    CAS  Google Scholar 

  28. Snyder TE, Krantz KE (1991) Abdominal–retroperitoneal sacral colpopexy for the correction of vaginal prolapse. Obstet Gynecol 77:944–949

    PubMed  CAS  Google Scholar 

  29. Valaitis SR, Stanton SL (1994) Sacrocolpopexy: a retrospective study of a clinician’s experience. Br J Obstet Gynaecol 101:518–522

    PubMed  CAS  Google Scholar 

  30. Kohli N, Walsh PM, Roat TW, Karram MM (1998) Mesh erosion after abdominal sacrocolpopexy. Obstet Gynecol 92:999–1004

    Article  PubMed  CAS  Google Scholar 

  31. Visco AG, Weidner AC, Barber MD, Myers ER, Cundiff GW, Bump RC, Addison WA (2001) Vaginal mesh erosion after abdominal sacral colpopexy. Am J Obstet Gynecol 184:297–302

    Article  PubMed  CAS  Google Scholar 

  32. Brizzolara S, Pillai-Allen A (2003) Risk of mesh erosion with sacral colpopexy and concurrent hysterectomy. Obstet Gynecol 102:306–310

    Article  PubMed  Google Scholar 

  33. Nygaard IE, McCreery R, Brubaker L et al (2004) Abdominal sacrocolpopexy: a comprehensive review. Obstet Gynecol 104(4):805–823

    PubMed  Google Scholar 

  34. Mattox TF, Stanford EJ, Varner E (2004) Infected abdominal sacrocolpopexies: diagnosis and treatment. Int Urogynecol J Pelvic Floor Dysfunct 15:319–323

    PubMed  Google Scholar 

  35. Salman MM, Hancock AL, Hussein AA, Hartwell R (2003) Lumbosacral spondylodiscitis: an unreported complication of sacrocolpopexy using mesh. BJOG 110:537–538

    Article  PubMed  CAS  Google Scholar 

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Acknowledgement

There is no declaration of interest. This study was not sponsored by manufacturers.

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Authors and Affiliations

  1. Service de Gynécologie-Obstétrique, Hôpital Antoine Béclère, 157, rue de la Porte-de-Trivaux, BP 405, 92140, Clamart, France

    X. Deffieux, C. Huel, A. Gervaise, K. Bonnet, R. Frydman & H. Fernandez

  2. Service de Gynécologie Obstétrique, Centre Hospitalier Universitaire de Nîmes, Groupe Hospitalo-Universitaire Caremeau, Place du Professeur Robert Debré, 029, Nîmes, Cedex Nimes, France

    R. de Tayrac

  3. DBIM Département de Biostatistique et d’Informatique Médicale, Hôpital Saint Louis, 1 ave Claude Vellefaux, 75010, Paris, France

    J. Bottero

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  1. X. Deffieux
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  2. R. de Tayrac
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  3. C. Huel
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  4. J. Bottero
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  5. A. Gervaise
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  6. K. Bonnet
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  7. R. Frydman
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  8. H. Fernandez
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Correspondence to X. Deffieux.

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Deffieux, X., de Tayrac, R., Huel, C. et al. Vaginal mesh erosion after transvaginal repair of cystocele using Gynemesh or Gynemesh-Soft in 138 women: a comparative study. Int Urogynecol J 18, 73–79 (2007). https://doi.org/10.1007/s0192-005-0041-2

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  • DOI: https://doi.org/10.1007/s0192-005-0041-2

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