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Preinterventional imaging strategies for patients with peripheral arterial disease

Is duplex ultrasound examination adequate for clinical decision-making? English version

Strategien für die präinterventionelle Bildgebung bei peripherer arterieller Verschlusskrankheit

Reicht die Duplex-Sonographie zur klinischen Entscheidungsfindung aus?

  • Vascular sonography
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Abstract

Background

In peripheral arterial disease (PAD) it is necessary to obtain precise anatomical and functional information of the patient prior to an intervention. Traditionally digital subtraction angiography (DSA) is the gold standard but recently contrast-enhanced magnetic resonance angiography (CE-MRA), color-coded duplex ultrasound (DUS) and contrast-enhanced high speed multi-row computed tomography angiography (CT-A) are now additionally available.

Objective

The aim of this article is to give a review of the currently available techniques for obtaining detailed patient information prior to an intervention and to compare these techniques with respect to diagnostic performance and clinical usefulness.

Material and methods

A literature search was carried out in PubMed with respect to English language articles involving studies on the effectiveness of preinterventional imaging methods for the identification and characterization of PAD. The imaging techniques were evaluated with respect to the usefulness under various clinically relevant situations for decision-making and planning of interventions.

Results and conclusion

Selection of the appropriate imaging modality for PAD has become more sophisticated and needs to be made on an individual basis depending on the particular requirements and situation of the patient. Each of the methods described here have advantages and disadvantages, which must be weighed up against the patient situation. Of all the methods, DUS would appear to be more universally applicable if available. Duplex ultrasound only rarely needs support from other imaging methods for clinical decision-making. 

Zusammenfassung

Hintergrund

Bei Patienten mit peripherer arterieller Verschlusskrankheit („peripheral arterial disease“, PAD) ist es erforderlich, genaue anatomische und funktionelle Befunde vor einer Intervention zu gewinnen. Der Goldstandard ist traditionell die digitale Subtraktionsangiographie (DSA), inzwischen stehen jedoch auch die kontrastverstärkte Magnetresonanztomographie (CE-MRA), die farbkodierte Duplexsonographie (DUS) und die kontrastverstärkte, Hochgeschwindigkeits-Mehrzeilen-Detektor CT-Angiographie (CT-A) zur Verfügung.

Ziele

Ziel des Review-Beitrags ist eine Übersicht über die derzeit verfügbaren Techniken zur Gewinnung möglichst detaillierter Information vor einer operativen Intervention. Ferner werden die Techniken im Hinblick auf diagnostische Performance und klinischen Nutzen miteinander verglichen.

Materialen und Methoden

Eine PubMed-Recherche wurde durchgeführt, gesucht wurde dabei nach englischsprachigen Artikeln über Studien zur Effektivität periinterventioneller bildgebender Verfahren für die Identifikation und Charakterisierung einer peripheren Verschlusskrankheit. Die bildgebenden Verfahren wurden evaluiert im Hinblick auf ihren Nutzen für Entscheidungen und für die Planung von Operationen in verschiedenen klinisch relevanten Situationen.

Ergebnisse und Schlüssfolgerungen

Die Entscheidung für eine geeignete bildgebende Modalität bei PAD ist komplizierter geworden, und sie muss auf individueller Basis getroffen werden, je nach der Situation des Patienten und seiner spezifischen Bedürfnisse. Jede der beschriebenen Verfahren hat Vor- und Nachteile, vor dem Hintergrund der Patientensituation sind sie gegeneinander abzuwägen sind. Falls sie zur Verfügung steht, scheint am ehesten die DUS („color-coded duplex ultrasound“) universell einsetzbar. Duplex ultrasound benötigt nur selten Unterstützung durch weitere Methoden, wenn es um die präinterventionelle klinische Entscheidungsfindung geht.

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References

  1. Adriaensen ME, Kock MC, Stijnen T, van Sambeek MR, van Urk H, Pattynama PM, Myriam Hunink MG (2004) Peripheral arterial disease: therapeutic confidence of CT versus digital subtraction angiography and effects on additional imaging recommendations. Radiology 233:385–391

    Article  PubMed  Google Scholar 

  2. Aly S, Shoab S, Bishop C (1999) Inter-observer variation. An alternative method of assessing the role of ultrasonic imaging in clinical decision-making in lower limb arterial disease. Int Angiol 18:220–224

    CAS  PubMed  Google Scholar 

  3. Ascher E, Hingorani A, Markevich N, Costa T, Kallakuri S, Khanimoy Y (2002) Lower extremity revascularization without preoperative contrast arteriography: experience with duplex ultrasound arterial mapping in 485 cases. Ann Vasc Surg 16:108–114

    Article  PubMed  Google Scholar 

  4. Collins R, Burch J, Cranny G, Aguiar-Ibáñez R, Craig D, Wright K, Berry E, Gough M, Kleijnen J, Westwood M (2007) Duplex ultrasonography, magnetic resonance angiography, and computed tomography angiography for diagnosis and assessment of symptomatic, lower limb peripheral arterial disease: systematic review. BMJ 334:1257

    Article  PubMed Central  PubMed  Google Scholar 

  5. Duan Y, Wang X, Yang X, Wu D, Cheng Z, Wu L (2013) Diagnostic efficiency of low-dose. CT angiography compared with conventional angiography in peripheral arterial occlusions. AJR Am J Roentgenol 201:W906–W914

    Article  PubMed  Google Scholar 

  6. Eiberg JP, Madycki G, Hansen MA, Christiansen S, Gronvall Rasmussen JB, Schroeder TV (2002) Ultrasound imaging of infrainguinal arterial disease has a high interobserver agreement. Eur J Vasc Endovasc Surg 24:293–299

    Article  CAS  PubMed  Google Scholar 

  7. Elsman BH, Legemate DA, van der Heijden FH, de Vos HJ, Mali WP, Eikelboom BC (1995) Impact of ultrasonographic duplex scanning on therapeutic decision making in lower-limb arterial disease. Br J Surg 82:630–633

    Article  CAS  PubMed  Google Scholar 

  8. Grassbaugh JA, Nelson PR, Rzucidlo EM, Schermerhorn ML, Fillinger MF, Powell RJ, Zwolak RM, Cronenwett JL, Walsh DB (2003) Blinded comparison of preoperative duplex ultrasound scanning and contrast arteriography for planning revascularization at the level of the tibia. J Vasc Surg 37:1186–1190

    Article  PubMed  Google Scholar 

  9. Hirsch AT, Haskal ZJ, Hertzer NR, Bakal CW, Creager MA, Halperin JL, Hiratzka LF, Murphy WR, Olin JW, Puschett JB, Rosenfield KA, Sacks D, Stanley JC, Taylor LM Jr, White CJ, White J, White RA, Antman EM, Smith SC Jr, Adams CD, Anderson JL, Faxon DP, Fuster V, Gibbons RJ, Hunt SA, Jacobs AK, Nishimura R, Ornato JP, Page RL, Riegel B, American Association for Vascular Surgery; Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, ACC/AHA Task Force on Practice Guidelines Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease, American Association of Cardiovascular and Pulmonary Rehabilitation, National Heart, Lung, and Blood Institute, Society for Vascular Nursing, TransAtlantic Inter-Society Consensus, Vascular Disease Foundation (2006) ACC/AHA 2005 practice guidelines for the management of patients with peripheral arterial disease (lower extremity, renal, mesenteric, and abdominal aortic): a collaborative report from the American Association for Vascular Surgery/Society for Vascular Surgery, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, Society of Interventional Radiology, and the ACC/AHA Task Force on Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Peripheral Arterial Disease): endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation; National Heart, Lung, and Blood Institute; Society for Vascular Nursing; TransAtlantic Inter-Society Consensus; and Vascular Disease Foundation. Circulation 113:e463–e654

    Article  PubMed  Google Scholar 

  10. Hofmann WJ, Walter J, Ugurluoglu A, Czerny M, Forstner R, Magometschnigg H (2004) Preoperative high-frequency duplex scanning of potential pedal target vessels. J Vasc Surg 39:169–175

    Article  CAS  PubMed  Google Scholar 

  11. Ihlberg L, Albäck A, Roth WD, Edgren J, Lepäntalo M (2000) Interobserver agreement in duplex scanning for vein grafts. Eur J Vasc Endovasc Surg 19:504–508

    Article  CAS  PubMed  Google Scholar 

  12. Jens S, Koelemay MJ, Reekers JA, Bipat S (2013) Diagnostic performance of computed tomography angiography and contrast-enhanced magnetic resonance angiography in patients with critical limb ischaemia and intermittent claudication: systematic review and meta-analysis. Eur Radiol 23:3104–3114

    Article  PubMed  Google Scholar 

  13. Koelemay MJ, den Hartog D, Prins MH, Kromhout JG, Legemate DA, Jacobs MJ (1996) Diagnosis of arterial disease of the lower extremities with duplex ultrasonography. Br J Surg 83:404–409

    Article  CAS  PubMed  Google Scholar 

  14. Koelemay MJ, Legemate DA, van Gurp JA, de Vos H, Balm R, Jacobs MJ (2001) Interobserver variation of colour duplex scanning of the popliteal, tibial and pedal arteries. Eur J Vasc Endovasc Surg 21:160–164

    Article  CAS  PubMed  Google Scholar 

  15. Koelemay MJ, Legemate DA, de Vos H, van Gurp AJ, Balm R, Reekers JA, Jacobs MJ (2001) Duplex scanning allows selective use of arteriography in the management of patients with severe lower leg arterial disease. J Vasc Surg 34:661–667

    Article  CAS  PubMed  Google Scholar 

  16. Koelemay MJ, Lijmer JG, Stoker J, Legemate DA, Bossuyt PM (2001) Magnetic resonance angiography for the evaluation of lower extremity arterial disease: a meta-analysis. JAMA 285:1338–1345

    Article  CAS  PubMed  Google Scholar 

  17. Langer S, Krämer N, Mommertz G, Koeppel TA, Jacobs MJ, Wazirie NA, Ocklenburg C, Spüntrup E (2009) Unmasking pedal arteries in patients with critical ischemia using time-resolved contrast-enhanced 3D MRA. J Vasc Surg 49:1196–1202

    Article  PubMed  Google Scholar 

  18. Lundin P, Svensson A, Henriksen E, Jonason T, Forssell C, Backbro B, Bodlund M, Ringqvist I (2000) Imaging of aortoiliac arterial disease. Duplex ultrasound and MR angiography versus digital subtraction angiography. Acta Radiol 41:125–132

    Article  CAS  PubMed  Google Scholar 

  19. Meissner OA, Verrel F, Tato F, Siebert U, Ramirez H, Ruppert V, Schoenberg SO, Reiser M (2004) Magnetic resonance angiography in the follow-up of distal lower-extremity bypass surgery: comparison with duplex ultrasound and digital subtraction angiography. J Vasc Interv Radiol 15:1269–1277

    Article  PubMed  Google Scholar 

  20. Nelemans PJ, Leiner T, de Vet HC, van Engelshoven JM (2000) Peripheral arterial disease: meta-analysis of the diagnostic performance of MR angiography. Radiology 217:105–114

    Article  CAS  PubMed  Google Scholar 

  21. Schäberle W, Rupp-Heim G, Leyerer L (2013) Duplexsonographische Diagnostik von Beckenarterienstenosen. Stenosegraduierung und zeiteffizientes Vorgehen durch Spektralanalyse. Gefaesschirurgie 18:44–51

    Article  Google Scholar 

  22. Ubbink DT, Fidler M, Legemate DA (2001) Interobserver variability in aortoiliac and femoropopliteal duplex scanning. J Vasc Surg 33:540–545

    Article  CAS  PubMed  Google Scholar 

  23. Vavrik J, Rohrmoser GM, Madani B, Ersek M, Tscholakoff D, Bucek RA (2004) Comparison of MR angiography versus digital subtraction angiography as a basis for planning treatment of lower limb occlusive disease. J Endovasc Ther 11:294–301

    Article  PubMed  Google Scholar 

  24. Visser K, Hunink MG (2000) Peripheral arterial disease: gadolinium-enhanced MR angiography versus color-guided duplex US–a meta-analysis. Radiology 216:67–77

    Article  CAS  PubMed  Google Scholar 

  25. Visser K, Kuntz KM, Donaldson MC, Gazelle GS, Hunink MG (2003) Pretreatment imaging workup for patients with intermittent claudication: a cost-effectiveness analysis. J Vasc Interv Radiol 14:53–62

    PubMed  Google Scholar 

  26. Vos MS de, Bol BJ, Gravereaux EC, Hamming JF, Nguyen LL (2014) Treatment planning for peripheral arterial disease based on duplex ultrasonography and computed tomography angiography: consistency, confidence and the value of additional imaging. Surgery 156:492–502

    Article  PubMed  Google Scholar 

  27. Vries M de, Ouwendijk R, Flobbe K, Nelemans PJ, Kessels AG, Schurink GH, van der Vliet JA, Heijstraten FM, Cuypers PW, Duijm LE, van Engelshoven JM, Hunink MG, de Haan MW (2006) Peripheral arterial disease: clinical and cost comparisons between duplex US and contrast-enhanced MR angiography–a multicenter randomized trial. Radiology 240:401–410

    Article  PubMed  Google Scholar 

  28. Willmann JK, Mayer D, Banyai M, Desbiolles LM, Verdun FR, Seifert B, Marincek B, Weishaupt D (2003) Evaluation of peripheral arterial bypass grafts with multi-detector row CT angiography: comparison with duplex US and digital subtraction angiography. Radiology 229:465–474

    Article  PubMed  Google Scholar 

  29. Wong TH, Tay KH, Sebastian MG, Tan SG (2013) Duplex ultrasonography arteriography as first-line investigation for peripheral vascular disease. Singapore Med J 54:271–274

    Article  PubMed  Google Scholar 

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Correspondence to P. Klein-Weigel M.D..

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P. Klein-Weigel, J. Fish and G. Fraedrich declare that there are no conflicts of interest.

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Klein-Weigel, P., Fish, J. & Fraedrich, G. Preinterventional imaging strategies for patients with peripheral arterial disease. Gefässchirurgie 21 (Suppl 1), 24–29 (2016). https://doi.org/10.1007/s00772-015-0007-8

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  • DOI: https://doi.org/10.1007/s00772-015-0007-8

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