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Adulticide effect of Monticalia greenmaniana (Asteraceae) against Lutzomyia migonei (Diptera: Psychodidae)

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Abstract

Leishmaniasis is a public health problem that has been increasing year by year, with the further difficulty that an efficient control system is not available. Therefore, it is necessary to search for less contaminating and dangerous alternatives for controlling Leishmania transmitting sandflies. The purpose of this study was to evaluate the activity of Monticalia greenmaniana (Asteraceae) extracts and essential oil as an adulticide against Lutzomyia migonei (Diptera: Psychodidae) females, from a laboratory colony, in experimental conditions. Dry aerial parts of M. greenmaniana (Hieron) Jeffrey were used. Methanolic and aqueous extracts were prepared, and essential oil was obtained by hydrodistillation. Adulticide tests in pots, adulticide tests in cages, and knocked-down effects were determined. The results obtained demonstrated that methanolic and aqueous extracts produced adulticide activity. The essential oil from M. greenmaniana was proved to be the most toxic against L. migonei, with a 95 % death rate at a concentration of 0.01 mg/ml during a 1-h exposure. The essential oil showed a DL50 = 0.0050 and DL98 = 0.0066 mg/ml. The methanolic extract was DL50 = 0.130 and DL98 = 1.016 mg/ml, and the aqueous extract, DL50 = 0.487 and DL98 10.924 mg/ml. The knocked-down effect for the M. greenmaniana oil showed a KDTL50 = 48.6 and KDTL98 = 90.1 min. It was concluded that the essential oil from M. greenmaniana showed a strong insecticide effect against L. migonei females, which encourages us to continue these studies in search for control alternatives against sandflies.

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Acknowledgments

The authors would like to thank Prof. Pablo Melendez for his collaboration in identifying the plant material and CDCHTA project codes C-1604-08-03-A and FA-456-09-03-EM of the Universidad de Los Andes for financial support.

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Authors and Affiliations

  1. LAPEX-Experimental Parasitology Laboratory, Biology Department, Science Faculty, Universidad de Los Andes, Merida, Venezuela

    José Cárdenas, Maritza Rondón & Elsa Nieves

  2. Organic Biomolecular Research Group, Research Institute, Pharmacy and Bioanalysis Faculty, Universidad de Los Andes, Merida, Venezuela

    José Cárdenas & Janne Rojas

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  1. José Cárdenas
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Correspondence to Elsa Nieves.

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Cárdenas, J., Rojas, J., Rondón, M. et al. Adulticide effect of Monticalia greenmaniana (Asteraceae) against Lutzomyia migonei (Diptera: Psychodidae). Parasitol Res 111, 787–794 (2012). https://doi.org/10.1007/s00436-012-2901-2

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