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Contribution of magnetic resonance imaging of the wrist and hand to forensic age assessment

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Abstract

Forensic age estimation of living individuals is a controversial subject because of the imprecision of the available methods which leads to errors. Moreover, young persons are exposed to radiation, without diagnostic or therapeutic advantage. Recently, non-invasive imaging techniques such as magnetic resonance imaging (MRI) have been studied in this context. The aim of this work was to study if the analysis of wrist/hand MRI enabled determination of whether a subject was 18 years old. Two observers retrospectively analyzed metaphyseal–epiphyseal fusion of the distal epiphysis of the radius and the ulna and the base of the first metacarpus in wrist/hand MRI of living people between 9 and 25 years of age. A three-stage scoring system was applied to all epiphyses. Intra- and inter-observer variability was excellent. Staging of the distal radial epiphysis allowed the subjects to be correctly evaluated with regard to the 18-year-old threshold in more than 85 % of cases. Analysis of the radius alone was as good as the analysis of the three epiphyses together. Evaluation of the metaphyseal–epiphyseal fusion of the distal radius in wrist MRI gave good results in forensic age estimation. Wrist MRI could meet ethical expectations with regard to the link between the benefit and risk of practicing radiologic examination on individuals in this context.

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References

  1. Schmeling A, Reisinger W, Loreck D, Vendura K, Markus W, Geserick G (2000) Effects of ethnicity on skeletal maturation: consequences for forensic age estimations. Int J Legal Med 113:253–258

    Article  CAS  Google Scholar 

  2. Schmeling A, Grundmann C, Fuhrmann A, Kaatsch HJ, Knell B, Ramsthaler F, Reisinger W, Riepert T, Ritz-Timme S, Rösing FW, Rötzscher K, Geserick G (2008) Criteria for age estimation in living individuals. Int J Legal Med 122:457–460

    Article  CAS  Google Scholar 

  3. Khan KM, Miller BS, Hoggard E, Somani A, Sarafoglou K (2009) Application of ultrasound for bone age estimation in clinical practice. J Pediatr 154:243–247

    Article  Google Scholar 

  4. Schmidt S, Schiborr M, Pfeiffer H, Schmeling A, Schulz R (2013) Age dependence of epiphyseal ossification of the distal radius in ultrasound diagnostics. Int J Legal Med 127:831–838

    Article  CAS  Google Scholar 

  5. Terada Y, Kono S, Tamada D, Uchiumi T, Kose K, Miyagi R, Yamabe E, Yoshioka H (2013) Skeletal age assessment in children using an open compact MRI system. Magn Reson Med 69:1697–1702

    Article  Google Scholar 

  6. Hillewig E, Degroote J, Van der Paelt T, Visscher A, Vandemaele P, Lutin B, D’Hooghe L, Vandriessche V, Piette M, Verstraete K (2013) Magnetic resonance imaging of the sternal extremity of the clavicle in forensic age estimation: towards more sound age estimates. Int J Legal Med 127:677–689

    Article  CAS  Google Scholar 

  7. Tangmose S, Jensen KE, Villa C, Lynnerup N (2014) Forensic age estimation from the clavicle using 1.0 T MRI—preliminary results. Forensic Sci Int 234:7–12

    Article  Google Scholar 

  8. Dedouit F, Auriol J, Rousseau H, Rougé D, Crubézy E, Telmon N (2012) Age assessment by magnetic resonance imaging of the knee: a preliminary study. Forensic Sci Int 217:232.e1–232.e7

    Article  Google Scholar 

  9. Krämer JA, Schmidt S, Jürgens KU, Lentschig M, Schmeling A, Vieth V (2014) Forensic age estimation in living individuals using 3.0T MRI of the distal femur. Int J Legal Med 128:509–514

    Article  Google Scholar 

  10. Krâmer JA, Schmidt S, Jürgens KU, Lentschig M, Schmeling A, Vieth V (2014) The use of magnetic resonance imaging to examine ossification of the proximal tibial epiphysis for forensic age estimation in living individuals. Forensic Sci Med Pathol 10:306–313

    Article  Google Scholar 

  11. Saint-Martin P, Rérolle C, Dedouit F, Bouilleau L, Rousseau H, Rougé D, Telmon N (2013) Age estimation by magnetic resonance imaging of the distal tibial epiphysis and the calcaneum. Int J Legal Med 127:1023–1030

    Article  Google Scholar 

  12. Dvorak J, George J, Junge A, Hodler J (2007) Age determination by magnetic resonance imaging of the wrist in adolescent male football players. Br J Sports Med 41:45–52

    Article  Google Scholar 

  13. Dvorak J, George J, Junge A, Hodler J (2007) Application of MRI of the wrist for age determination in international U-17 soccer competitions. Br J Sports Med 41:497–500

    Article  Google Scholar 

  14. Dvorak J (2009) Detecting over-age players using wrist MRI: science partnering with sport to ensure fair play. Br J Sports Med 43:884–885

    Article  Google Scholar 

  15. Schmidt S, Vieth V, Timme M, Junge A, Dvorak J, Schmeling A (2014) Examination of ossification of the distal radial epiphysis using magnetic resonance imaging. New insights for age estimation in young footballers in FIFA tournaments. Sci Justice 55:139–144

    Article  Google Scholar 

  16. Jopp E, Schröder I, Maas R, Adam G, Püschel K, Hertzog C (2010) Proximale Tibiaepiphyse im Magnetresonanztomogramm. Rechtsmedizin 20:464–468

    Article  Google Scholar 

  17. Development Core Team R (2008) R: a language and environment for statistical computing. R Foundation For Statistical Computing, Vienna

    Google Scholar 

  18. Cohen J (1960) A coefficient of agreement for nominal scales. Educ Psychol Meas 20:37–46

    Article  Google Scholar 

  19. Ferrante L, Cameriere R (2009) Statistical methods to assess the reliability of measurements in the procedures for forensic age estimation. Int J Legal Med 123:277–283

    Article  CAS  Google Scholar 

  20. Hoppa RD, Vaupel JW (2002) Paleodemography: age distribution from skeletal sample. Cambridge University Press, New York

    Book  Google Scholar 

  21. Hartigan JA (1983) Bayes theory. Springer, New York

    Book  Google Scholar 

  22. Tersigni-Tarrant MTA, Shirley NR (2012) Forensic anthropology: an introduction. Taylor & Francis Inc., Galway

    Google Scholar 

  23. Serinelli S, Panebianco V, Martino M, Battisti S, Rodacki K, Marinelli E, Zaccagna F, Semelka RC, Tomei E (2015) Accuracy of MRI skeletal age estimation for subjects 12–19. Potential use for subjects of unknown age. Int J Legal Med 129:609–617

    Article  Google Scholar 

  24. Tscholl PM, Junge A, Dvorak J, Zubler V (2015) MRI of the wrist is not recommended for age determination in female football players of U-16/U-17 competitions. Scand J Med Sci Sports. doi:10.1111/sms.12461

  25. Cameriere R, De Luca S, De Angelis D, Merelli V, Giuliodori M, Cattaneo C, Ferrante L (2012) Reliability of Schmeling’s stages of ossification of medial clavicular epiphysis and its validity to assess 18 years of age in living subjects. Int J Legal Med 126:923–932

    Article  CAS  Google Scholar 

  26. Kellinghaus M, Schulz R, Vieth V, Schmidt S, Pfeiffer H, Schmeling A (2010) Enhanced possibilities to make statements on the ossification status of the medial clavicular epiphysis using an amplified staging scheme in evaluating thin-slice CT scans. Int J Legal Med 124:321–325

    Article  Google Scholar 

  27. Wittschieber D, Schmeling A, Schmidt S, Heindel W, Pfeiffer H, Vieth V (2013) The Risser sign for forensic age estimation in living individuals: a study of 643 pelvic radiographs. Forensic Sci Med Pathol 9:36–43

    Article  Google Scholar 

  28. Hackman L, Black S (2012) Does mirror imaging a radiograph affect reliability of age assessment using the Greulich and Pyle atlas? J Forensic Sci 57:1276–1280

    Article  Google Scholar 

  29. Schmidt S, Koch B, Schulz R, Reisinger W, Schmeling A (2008) Studies in use of the Greulich-Pyle skeletal age method to assess criminal liability. Leg Med (Tokyo) 10:190–195

    Article  Google Scholar 

  30. Kellinghaus M, Schulz R, Vieth V, Schmidt S, Schmeling A (2010) Forensic age estimation in living subjects based on the ossification status of the medial clavicular epiphysis as revealed by thin-slice multidetector computed tomography. Int J Legal Med 124:149–154

    Article  Google Scholar 

  31. Bassed RB, Drummer OH, Briggs C, Valenzuela A (2011) Age estimation and the medial clavicular epiphysis: analysis of the age of majority in an Australian population using computed tomography. Forensic Sci Med Pathol 7:148–154

    Article  Google Scholar 

  32. Schulz R, Mühler M, Mutze S, Schmidt S, Reisinger W, Schmeling A (2005) Studies on the time frame for ossification of the medial epiphysis of the clavicle as revealed by CT scans. Int J Legal Med 119:142–145

    Article  Google Scholar 

  33. Schulze D, Rother U, Fuhrmann A, Richel S, Faulmann G, Heiland M (2006) Correlation of age and ossification of the medial clavicular epiphysis using computed tomography. Forensic Sci Int 158:184–189

    Article  Google Scholar 

  34. Schmidt S, Mühler M, Schmeling A, Reisinger W, Schulz R (2007) Magnetic resonance imaging of the clavicular ossification. Int J Legal Med 121:321–324

    Article  Google Scholar 

  35. Hillewig E, Tobel J, Cuche O, Vandemaele P, Piette M, Verstraete K (2011) Magnetic resonance imaging of the medial extremity of the clavicle in forensic bone age determination: a new four-minute approach. Eur Radiol 21:757–767

    Article  Google Scholar 

  36. Schmeling A, Schulz R, Danner B, Rösing FW (2006) The impact of economic progress and modernization in medicine on the ossification of hand and wrist. Int J Legal Med 120:121–126

    Article  Google Scholar 

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Correspondence to Jeanne Serin.

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Serin, J., Rérolle, C., Pucheux, J. et al. Contribution of magnetic resonance imaging of the wrist and hand to forensic age assessment. Int J Legal Med 130, 1121–1128 (2016). https://doi.org/10.1007/s00414-016-1362-z

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  • DOI: https://doi.org/10.1007/s00414-016-1362-z

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