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Magnetic resonance imaging of the medial extremity of the clavicle in forensic bone age determination: a new four-minute approach

  • Forensic Medicine
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Abstract

Objectives

The use of 3T magnetic resonance imaging (MRI) of the clavicle in forensic bone age determination was prospectively examined and compared with plain radiography.

Methods

Four MRI sequences and three radiographs of 121 healthy subjects between 11 and 30 were studied by two observers.

Results

The number of images assessable for bone age determination was lower for plain radiography (PA: 68.7%; oblique: 97.5%) compared with MRI (VIBE: 99.0%). Concerning the subjective level of difficulty to assess bone age, the observers found it easier to assess bone age on MRI than on radiography. The developmental stages of the clavicle, as used on plain radiography, were transferable to MRI. Especially the VIBE gradient echo sequence provided an excellent depiction of the growth cartilage and ossification centre with a slice thickness of 0.9 mm and only a 4-min acquisition time. When the developmental stages were assigned, less variability between the observers was seen on MRI, compared with plain radiography.

Conclusion

We conclude that 3T MRI provides high resolution, cross-sectional images of the maturation of the clavicle without ionising radiation in a very short time, allowing more accurate determination of bone age than plain radiography.

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References

  1. Schmeling A, Geserick G, Reisinger W, Olze A (2007) Age estimation. Forensic Sci Int 165:178–181. doi:10.1016/j.forsciint.2006.05.016

    Article  PubMed  CAS  Google Scholar 

  2. Schmeling A, Kaatsch HJ, Marre B et al (2001) Empfehlungen für die Alterdiagnostik bei Lebenden im Strafverfahren. Rechtsmedizin 11:1–3

    Article  Google Scholar 

  3. Schmeling A, Reisinger W, Geserick G, Olze A (2006) Age estimation of unaccompanied minors—Part I: general considerations. Forensic Sci Int 159:S61–S64

    Article  PubMed  Google Scholar 

  4. Schulz R, Mühler M, Reisinger W, Schmidt S, Schmeling A (2008) Radiographic staging of ossification of the medial clavicular epiphysis. Int J Leg Med 122:55–58. doi:10.1007/s00414-007-0210-6

    Article  Google Scholar 

  5. Lockemann U, Fuhrmann A, Puschel K, Schmeling A, Geserick G (2004) Empfehlungen für die Alterdiagnostik bei Jugendlichen und jungen Erwachsenen ausserhalb des Strafverfahrens. Rechtsmedizin 14:123–125

    Article  Google Scholar 

  6. Schmidt S, Muhler M, Schmeling A, Reisinger W, Schulz R (2007) Magnetic resonance imaging of the clavicular ossification. Int J Leg Med 121:321–324. doi:10.1007/s00414-007-0160-z

    Article  Google Scholar 

  7. Dutch Ministry of Justice, Netherlands Forensic Institute (2008) Age Investigation Protocol. Dutch Ministry of Justice and the Netherlands Forensic Institute, The Netherlands. Available via http://www.forensischinstituut.nl. Accessed 3 June 2010

  8. Schmeling A, Schulz R, Reisinger W, Muhler M, Wernecke KD, Geserick G (2004) Studies on the time frame for ossification of the medial clavicular epiphyseal cartilage in conventional radiography. Int J Leg Med 118:5–8. doi:10.1007/s00414-003-0404-5

    Article  Google Scholar 

  9. Ludescher B, Martirosian P, Lenk S, Machann J, Dammann F, Schick F, Claussen C, Schlemmer H (2005) High-resolution magnetic resonance imaging of trabecular bone in the wrist at 3T: initial results. Acta Radiol 46:306–305. doi:10.1080/02841850510021076

    Article  PubMed  CAS  Google Scholar 

  10. Soher B, Dale B, Merkle E (2007) A review of MR physics: 3T versus 1.5T. Magn Reson imaging Clin N Am 15:277–290. doi:10.1016/j.mric.2007.06.002

    Article  PubMed  Google Scholar 

  11. Bauer J, Krause S, Ross C, Krug R, Carballido-Gamio J, Ozhinsky E, Majumdar S, Link T (2006) Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy. Radiology 241:399–406

    Article  PubMed  Google Scholar 

  12. Blamire A (2008) The technology of MRI-the next 10 years. Br J Radiol 81:601–617. doi:10.1259/bjr/96872829

    Article  PubMed  CAS  Google Scholar 

  13. Kreitner KF, Schweden FJ, Riepert T, Nafe B, Thelen M (1998) Bone age determination based on the study of the medial extremity of the clavicle. Eur Radiol 8:1116–1122

    Article  PubMed  CAS  Google Scholar 

  14. Flecker H (1942) Time of appearance and fusion of ossification centers as observed by roentgenographic methods. AJR Am J Roentgenol 47:97–159

    Google Scholar 

  15. Destouet JM, Gilula LA, Murphy WA, Sagel SS (1981) Computed-tomography of the sternoclavicular joint and sternum. Radiology 138:123–128

    PubMed  CAS  Google Scholar 

  16. Lucet L, LeLoet X, Menard JF et al (1996) Computed tomography of the normal sternoclavicular joint. Skeletal Radiol 25:237–241

    Article  PubMed  CAS  Google Scholar 

  17. Robben S (2004) Uitspraak rechtbank ’s Gravenhage inzake leeftijdsonderzoek. Memorad 9:14–15

    Google Scholar 

  18. Ramsthaler F, Proschek P, Betz W, Verhoff MA (2009) How reliable are the risk estimates for X-ray examinations in forensic age estimations? A safety update. Int J Leg Med 123:199–204. doi:10.1007/s00414-009-0322-2

    Article  CAS  Google Scholar 

  19. Richardson DB, Wing S, Hoffmann W (2001) Cancer risk from low-level ionizing radiation: the role of age at exposure. State Art Rev Occup Med 16:191–218

    CAS  Google Scholar 

  20. Brenner DJ, Elliston CD, Hall EJ, Berdon WE (2001) Estimated risks of radiation-induced fatal cancer from pediatric CT. AJR Am J Roentgenol 176:289–296

    PubMed  CAS  Google Scholar 

  21. Jung H (2000) Strahlenrisiken durch Röntgenuntersuchungen zur Alterschätzung im strafverfahren. Fortschr Röntgenstr 172:553–556

    Article  CAS  Google Scholar 

  22. Schmeling A, Reisinger W, Wormanns D, Geserick G (2000) Strahlenexposition bei Röntgenuntersuchungen zur forensischen Alterschätzung Lebender. Rechtsmedizin 10:135–137

    Article  Google Scholar 

  23. Okkalides D, Fotakis M (1994) Patient effective dose resulting from radiographic examinations. Br J Radiol 67:564–572

    Article  PubMed  CAS  Google Scholar 

  24. Jurik AG, Jensen LC, Hansen J (1996) Radiation dose by spiral CT and conventional tomography of the sternoclavicular joints and the manubrium sterni. Skeletal Radiol 25:467–470

    Article  PubMed  CAS  Google Scholar 

  25. Schulz R, Zwiesigk P, Schiborr M, Schmidt S, Schmeling A (2008) Ultrasound studies on the time course of clavicular ossification. Int J Leg Med 122:163–167. doi:10.1007/s00414-007-0220-4

    Article  Google Scholar 

  26. Quirmbach F, Ramsthaler F, Verhoff MA (2009) Evaluation of the ossification of the medial clavicular epiphysis with a digital ultrasonic system to determine the age threshold of 21 years. Int J Leg Med 123:241–245. doi:10.1007/s00414-009-0335-x

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Radiology, Ghent University, Ghent, Belgium

    Elke Hillewig, J. De Tobel, O. Cuche, P. Vandemaele & K. Verstraete

  2. Department of Forensic Medicine, Ghent University, Ghent, Belgium

    M. Piette

Authors
  1. Elke Hillewig
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  2. J. De Tobel
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  3. O. Cuche
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  4. P. Vandemaele
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  5. M. Piette
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  6. K. Verstraete
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Correspondence to Elke Hillewig.

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Hillewig, E., De Tobel, J., Cuche, O. et al. Magnetic resonance imaging of the medial extremity of the clavicle in forensic bone age determination: a new four-minute approach. Eur Radiol 21, 757–767 (2011). https://doi.org/10.1007/s00330-010-1978-1

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  • DOI: https://doi.org/10.1007/s00330-010-1978-1

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