Abstract
Cerium (Ce)-based compounds, such as CeO2 nanoparticles (NPs), have received much attention in the last several years due to their popular applications in industrial and commercial uses. Understanding the impact of CeO2 NPs on nutrient cycles, a subchronic toxicity study of CeO2 NPs on soil-denitrification process was performed as a function of particle size (33 and 78 nm), total Ce concentration (50–500 mg L−1), and speciation [Ce(IV) vs. Ce(III)]. The antimicrobial effect on the soil-denitrification process was evaluated in both steady-state and zero-order kinetic models to assess particle- and chemical-species specific toxicity. It was found that soluble Ce(III) was far more toxic than Ce(IV)O2 NPs when an equal total concentration of Ce was evaluated. Particle size-dependent toxicity, species-dependent toxicity, and concentration-dependent toxicity were all observed in this study for both the steady-state and the kinetic evaluations. Changes in physicochemical properties of Ce(IV)O2 NPs might be important in assessing the environmental fate and toxicity of NPs in aquatic and terrestrial environments.
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Arnold MC, Badireddy AR, Wiesner MR, Di Giulio RT, Meyer JN (2013) Cerium oxide nanoparticles are more toxic than equimolar bulk cerium oxide in Caenorhabditis elegans. Arch Environ Contam Toxicol 65:224–233
Babu S, Velez A, Wozniak K, Szydlowska J, Seal S (2007) Electron paramagnetic study on radical scavenging properties of ceria nanoparticles. Chem Phys Lett 442:405–408
Balusamy B, Kandhasamy YG, Senthamizhan A, Chandrasekaran G, Subramanian MS, Tirukalikundram SK (2012) Characterization and bacterial toxicity of lanthanum oxide bulk and nanoparticles. J Rare Earths 30:1298–1302
Boaventura RAR, Rodrigues AE (1997) Denitrification kinetics in a rotating disk biofilm reactor. Chem Eng J 65:227–235
Carlson C, Hussain SM, Schrand AM, Braydich-Stolle LK, Hess KL, Jones RL et al (2008) Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species. J Phys Chem B 112:13608–13619
Choi O, Hu Z (2008) Size dependent and reactive oxygen species related nanosilver toxicity to nitrifying bacteria. Environ Sci Technol 42:4583–4588
Collin B, Oostveen E, Tsyusko OV, Unrine JM (2014) Influence of natural organic matter and surface charge on the toxicity and bioaccumulation of functionalized ceria nanoparticles in Caenorhabditis elegans. Environ Sci Technol 48:1280–1289
Cornelis G, Ryan B, McLaughlin MJ, Kirby JK, Beak D, Chittleborough D (2011) Solubility and batch retention of CeO2 nanoparticles in soils. Environ Sci Technol 45:2777–2782
Dahle JT (2012) Master’s thesis: the effects of physicochemical properties of CeO2 nanoparticles on toxicity to soil denitrification processes. Clemson University, Clemson
Dahle JT, Livi K, Arai Y (2014) Effects of pH and phosphate on CeO2 nanoparticle dissolution. Chemosphere. doi:10.1016/j.chemosphere.2014.02.027
Dawson RN, Murphy KL (1972) The temperature dependency of biological denitrification. Water Res 6:71–83
Gruner S, Sehrt I, Muller GM, Zwirner A, Strunk D, Sonnichsen N (1992) Inhibition of histamine-release from human granulocytes by ions of the rare-earth elements lanthanum and cerium. Agents Actions 36:207–211
He X, Kuang Y, Li Y, Zhang H, Ma Y, Bai W et al (2012) Changing exposure media can reverse the cytotoxicity of ceria nanoparticles for Escherichia coli. Nanotoxicology 6:233–240
Heckert EG, Karakoti AS, Seal S, Self WT (2008) The role of cerium redox state in the SOD mimetic activity of nanoceria. Biomaterials 29:2705–2709
Hendren CO, Mesnard X, Droge J, Wiesner MR (2011) Estimating production data for five engineered nanomaterials as a basis for exposure assessment. Environ Sci Technol 45:2562–2569
Hoecke KV, Quik JT, Mankiewicz-Boczek J, Schamphelaere K, Elsaesser A, Van der Meeren P et al (2009) Fate and effects of CeO2 nanoparticles in aquatic ecotoxicity tests. Environ Sci Technol 43:4537–4546
Hoshino A, Fujioka K, Oku T, Suga M, Sasaki YF, Ohta T et al (2004) Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification. Nano Lett 4:2163–2169
Institute Health Effects (2001) Evaluation of human health risk from cerium added to diesel fuel. Health Effects Institute Communication 9
Ivanov VK, Shcherbakov AB, Ryabokon IG, Usatenko AV, Zholobak NM, Tretyakov YD (2010) Inactivation of the nitroxyl radical by ceria nanoparticles. Dokl Chem 430:43–46
Jakupec MA, Unfried P, Keppler BK (2005) Pharmacological properties of cerium compounds. In: Amara SG, Bamberg E, Jahn R, Lederer WJ, Miyajima A, Murer H et al (eds) Reviews of physiology biochemistry and pharmacology. Springer-Verlag, Berlin, Heidelberg, New York, pp 101–111
Karakoti AS, Monteiro-Riviere NA, Aggarwal R, Davis JP, Narayan RJ, Self WT et al (2008) Nanoceria as antioxidant: synthesis and biomedical applications. JOM 60:33–37
Karlsson HL, Gustafsson J, Cronholm P, Moller L (2009) Size-dependent toxicity of metal oxide particles—a comparison between nano- and micrometer size. Toxicol Lett 188:112–118
Keller AA, McFerran S, Lazareva A, Suh S (2013) Global life-cycle releases of engineered nanomaterials. J Nanopart Res 15:1692–1704
Kuang YS, He X, Zhang ZY, Li YY, Zhang HF, Ma YH et al (2011) Comparison study on the antibacterial activity of nano- or bulk-cerium oxide. J Nanosci Nanotechnol 11:4103–4108
Lead JR, Smith E (2009) Environmental and human health impacts of nanotechnology. Wiley, Chichester
Limbach LK, Bereiter R, Mueller E, Krebs R, Gaelli R, Stark WJ (2008) Removal of oxide nanoparticles in a model wastewater treatment plant: influence of agglomeration and surfactants on clearing efficiency. Environ Sci Technol 42:5828–5833
Lu K, Zhang ZY, He XA, Ma YH, Zhou KB, Zhang HF et al (2010) Bioavailability and distribution and of ceria nanoparticles in simulated aquatic ecosystems, quantification with a radiotracer technique. J Nanosci Nanotechnol 10:8658–8662
Lubick N (2008) Nanosilver toxicity: ions, nanoparticles—or both? Environ Sci Technol 42:8617
Mahendra S, Zhu H, Colvin VL, Alvarez PJ (2008) Quantum dot weathering results in microbial toxicity. Environ Sci Technol 42:9424–9430
Nalabotu SK, Kolli MB, Triest WE, Ma JY, Manne N, Katta A et al (2011) Intratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague–Dawley rats. Int J Nanomed 6:2327–2335
Napierska D, Thomassen LCT, Rabolli V, Lison D, Gonzalez L, Kirsch-Volders M et al (2009) Size-dependent cytotoxicity of monodisperse silica nanoparticles in human endothelial cells. Small 5:846–853
Palasz A, Czekaj P (2000) Toxicological and cytophysiological aspects of lanthanides action. Acta Biochim Pol 47:1107–1114
Palmberg C, Tuomo N (2006) Industrial renewal and growth through nanotechnology? An overview with focus on Finland. ETLA Discussion Papers, The Research Institute of the Finnish Economy, number 1020
Pan Y, Neuss S, Leifert A, Fischler M, Wen F, Simon U et al (2007) Size-dependent cytotoxicity of gold nanoparticles. Small 3:1941–1949
Pelletier DA, Suresh AK, Holton GA, McKeown CK, Wang W, Gu BH et al (2010) Effects of engineered cerium oxide nanoparticles on bacterial growth and viability. Appl Environ Microbiol 76:7981–7989
Pirmohamed T, Dowding JM, Singh S, Wasserman B, Heckert E, Karakoti AS et al (2010) Nanoceria exhibit redox state-dependent catalase mimetic activity. Chem Commun 46:2736–2738
Rodea-Palomares I, Boltes K, Fernandez-Pinas F, Leganes F, Garcia-Calvo E, Santiago J et al (2011) Physicochemical characterization and ecotoxicological assessment of CeO2 nanoparticles using two aquatic microorganisms. Toxicol Sci 119:135–145
Rogers NJ, Franklin NM, Apte SC, Batley GE, Angel BM, Lead JR et al (2010) Physico-chemical behaviour and algal toxicity of nanoparticulate CeO2 in freshwater. Environ Chem 7:50–60
Roh J, Park Y, Park K, Choi J (2010) Ecotoxicological investigation of CeO2 and TiO2 nanoparticles on the soil nematode Caenorhabditis elegans using gene expression, growth, fertility, and survival as endpoints. Environ Toxicol Pharmacol 29:167–172
Rzigalinski BA, Bailey D, Chow L, Kuiry SC, Patil S, Merchant S et al (2003) Cerium oxide nanoparticles increase the lifespan of cultured brain cells and protect against free radical and mechanical trauma. FASEB J 17:A606
Thill A, Zeyons O, Spalla O, Chauvat F, Rose J, Auffan M et al (2006) Cytotoxicity of CeO2 nanoparticles for Escherichia coli. Physico-chemical insight of the cytotoxicity mechanism. Environ Sci Technol 40:6151–6156
United States Environmental Protection Agency, USEPA (2007) Protection of environment: standards for the use or disposal of sewage sludge—land application: pollutant limits, vol 40, pp 9–11
United States Environmental Protection Agency (2009) Toxicological review of cerium oxide and cerium compounds. USEPA, Washington, DC
van Haandel AC, Ekama GA, Marais GvR (1981) The activated sludge process. 3. Single sludge denitrification. Water Res 15:1135–1152
VandeVoort AR, Arai Y (2012) Effect of silver nanoparticles on soil denitrification kinetics. Ind Biotechnol 8:358–364
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This research was partially funded by the 2011 Agriculture and Food Research Initiative Competitive Grants Program, Nanotechnology for Agriculture and Food Systems (Grant No. 2011-03580).
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Dahle, J.T., Arai, Y. Effects of Ce(III) and CeO2 Nanoparticles on Soil-Denitrification Kinetics. Arch Environ Contam Toxicol 67, 474–482 (2014). https://doi.org/10.1007/s00244-014-0031-9
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DOI: https://doi.org/10.1007/s00244-014-0031-9