, Volume 91, Issue 8, pp 905-906
Date: 28 Jul 2013

Bioimaging for cardiometabolic translational medicine: from cellular messengers to organism function

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The twentieth century witnessed two great breakthroughs—Watson and Crick's discovery of the double-helix structure of DNA and the central dogma of the flow of genetic information. At the turn of this millennium, the Human Genome Program has led to an explosion of biomedical information and integration of physics, computational science, and engineering, thereby transforming the biomedical landscape and enabling the new biology of the twenty-first century. Understanding the structural and architectural dynamics of living organisms at the cellular and molecular levels has become a prime focus of biomedical research in the postgenomic era. The discipline of biomolecular imaging holds great promise for visualizing activities of biological systems in ever finer details while simultaneously obtaining multidimensional, multifaceted, panoramic views of the system as a whole. Biomolecular imaging is one of the main forces to facilitate a seamless unification of the reductionist approach with int